دورية أكاديمية
Three new chromones from the whole plants of Chamaecrista rotundifolia and their anti-rotavirus activities.
| العنوان: | Three new chromones from the whole plants of Chamaecrista rotundifolia and their anti-rotavirus activities. |
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| المؤلفون: | Yang PS; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., He XY; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China.; School of Animal Science and Technology, Southwest University, Chongqing, P. R. China., Li SS; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Huang DQ; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Shen SY; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Liu XS; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Ma YY; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China.; Yunnan Key Laboratory of Tobacco Chemistry, China Tobacco Yunnan Industrial Co., Ltd, Kunming, P.R. China., Dong M; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Zhou M; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China., Yang FX; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China.; Yunnan Key Laboratory of Tobacco Chemistry, China Tobacco Yunnan Industrial Co., Ltd, Kunming, P.R. China., Li YK; Key Laboratory of Natural Products Synthetic Biology of Ethnic Medicinal, State Ethnic Affairs Commission, Yunnan Minzu University, Kunming, P. R. China. |
| المصدر: | Natural product research [Nat Prod Res] 2024 Jul; Vol. 38 (14), pp. 2428-2435. Date of Electronic Publication: 2023 Feb 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Chromones*/chemistry , Chromones*/pharmacology , Antiviral Agents*/pharmacology , Antiviral Agents*/chemistry , Antiviral Agents*/isolation & purification, Molecular Structure ; Magnetic Resonance Spectroscopy ; China ; Plant Extracts/chemistry ; Plant Extracts/pharmacology |
| مستخلص: | Chamaecrista rotundifolia ( C. rotundifolia ) is a perennial herb of leguminosae, which increasingly being grown as a forage in China. In our search for original bioactive metabolites from Cassia plants, the phytochemical reinvestigation of the C. rotundifolia was carried out, which led to the isolation of three new ( 1 - 3 ) and six known ( 4 - 9 ) chromones. Their structures were confirmed by spectroscopic methods, including extensive 1D and 2D NMR techniques. Compounds 1 - 9 were evaluated for their anti-rotavirus activities, and the results revealed that compounds 1 - 9 exhibited potential anti-rotavirus activities with therapeutic index (TI) valves in the range of 12.0 ∼ 20.2, respectively. |
| فهرسة مساهمة: | Keywords: Chamaecrista rotundifolia; anti-rotavirus activities; chromones |
| المشرفين على المادة: | 0 (Chromones) 0 (Antiviral Agents) 0 (Plant Extracts) |
| تواريخ الأحداث: | Date Created: 20230214 Date Completed: 20240710 Latest Revision: 20240710 |
| رمز التحديث: | 20240710 |
| DOI: | 10.1080/14786419.2023.2177286 |
| PMID: | 36787178 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2023.2177286 |