دورية أكاديمية
New monoterpenoid indole alkaloids from the stems of Tabernaemontana bovina Lour (Apocynaceae).
| العنوان: | New monoterpenoid indole alkaloids from the stems of Tabernaemontana bovina Lour (Apocynaceae). |
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| المؤلفون: | Yan XW; School of Biological Science and Technology, University of Jinan, Jinan, China.; Key Laboratory of Natural Pharmaceutical Chemistry, Shandong University of Traditional Chinese Medicine, Jinan, China., Du SY; School of Biological Science and Technology, University of Jinan, Jinan, China.; Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Qingdao, China., Wang XT; PingYi County Traditional Chinese Medicine, Linyi, China., Zhu KK; School of Biological Science and Technology, University of Jinan, Jinan, China., Fang L; School of Biological Science and Technology, University of Jinan, Jinan, China.; Key Laboratory of Natural Pharmaceutical Chemistry, Shandong University of Traditional Chinese Medicine, Jinan, China. |
| المصدر: | Natural product research [Nat Prod Res] 2024 Jul; Vol. 38 (14), pp. 2447-2452. Date of Electronic Publication: 2023 Feb 14. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: | Plant Stems*/chemistry , Nitric Oxide* , Secologanin Tryptamine Alkaloids*/chemistry , Secologanin Tryptamine Alkaloids*/pharmacology , Secologanin Tryptamine Alkaloids*/isolation & purification , Tabernaemontana*/chemistry, Mice ; Animals ; RAW 264.7 Cells ; Molecular Structure ; Lipopolysaccharides/pharmacology ; Magnetic Resonance Spectroscopy ; Macrophages/drug effects |
| مستخلص: | Two new monoterpenoid indole alkaloids, named taberibogines E and F ( 1 and 2 ), together with three known ones ( 3 - 5 ) were isolated from the stems of Tabernaemontana bovina Lour (Apocynaceae). Their structures including absolute configurations were elucidated from a combination of NMR and HRESIMS data and NMR calculations as well as DP4+ probability analyses. Compounds 1 and 2 exhibited inhibitory effects on LPS-induced nitric oxide (NO) production in RAW 264.7 macrophages. |
| فهرسة مساهمة: | Keywords: Apocynaceae; Tabernaemontana bovina Lour; anti-inflammatory activity; monoterpenoid indole alkaloids |
| المشرفين على المادة: | 31C4KY9ESH (Nitric Oxide) 0 (Secologanin Tryptamine Alkaloids) 0 (Lipopolysaccharides) |
| تواريخ الأحداث: | Date Created: 20230214 Date Completed: 20240710 Latest Revision: 20240710 |
| رمز التحديث: | 20240710 |
| DOI: | 10.1080/14786419.2023.2180503 |
| PMID: | 36787196 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1478-6427 |
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| DOI: | 10.1080/14786419.2023.2180503 |