دورية أكاديمية
أعرض في EDS

Clinically Relevant Pancreatic Fistula after Pancreaticoduodenectomy: How We Do It.

التفاصيل البيبلوغرافية
العنوان: Clinically Relevant Pancreatic Fistula after Pancreaticoduodenectomy: How We Do It.
المؤلفون: Enderes J; Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany., Pillny C; Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany., Matthaei H; Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany., Manekeller S; Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany., Kalff JC; Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany., Glowka TR; Department of Surgery, University Hospital Bonn, 53127 Bonn, Germany.
المصدر: Biology [Biology (Basel)] 2023 Jan 22; Vol. 12 (2). Date of Electronic Publication: 2023 Jan 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101587988 Publication Model: Electronic Cited Medium: Print ISSN: 2079-7737 (Print) Linking ISSN: 20797737 NLM ISO Abbreviation: Biology (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, 2012-
مستخلص: (1) Background: This study's goals were to investigate possible risk factors for clinically relevant postoperative pancreatic fistula (POPF) grade B/C according to the updated definitions of the International Study Group of Pancreatic Surgery and to analyze possible treatment strategies; (2) Methods: Between 2017 and 2021, 200 patients were analyzed regarding the development of POPF grade B/C with an emphasis on postoperative outcome and treatment strategies; (3) Results: POPF grade B/C was observed in 39 patients (19.5%). These patients were younger, mainly male, had fewer comorbidities and showed a higher body mass index. Also, they had lower CA-19 levels, a smaller tumor size and softer pancreatic parenchyma. They experienced a worse outcome without affecting the overall mortality rate (10% vs. 6%, p = 0.481), however, this lead to a prolonged postoperative stay (28 (32-36) d vs. 20 (15-28) d, p ≤ 0.001). The majority of patients with POPF grade B/C were able to receive conservative treatment, followed by drainage placement, endoscopic vacuum-assisted therapy (EVT) and surgery. Conservative treatment resulted in a shorter length of the postoperative stay (24 (22-28) d vs. 34 (26-43) d, p = 0.012); (4) Conclusions: Patients developing POPF grade B/C had a worse outcome; however, this did not affect the overall mortality rate. The majority of the patients were able to receive conservative treatment, resulting in a shorter length of their hospital stay.
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فهرسة مساهمة: Keywords: Whipple; endoscopic vacuum-assisted therapy; pancreatic fistula; pancreaticoduodenectomy
تواريخ الأحداث: Date Created: 20230225 Latest Revision: 20230228
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9952935
DOI: 10.3390/biology12020178
PMID: 36829457
قاعدة البيانات: MEDLINE
الوصف
تدمد:2079-7737
DOI:10.3390/biology12020178