دورية أكاديمية
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Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo.

التفاصيل البيبلوغرافية
العنوان: Structural Characterization of Polysaccharides from Coriandrum sativum Seeds: Hepatoprotective Effect against Cadmium Toxicity In Vivo.
المؤلفون: Sfar M; Laboratory of Interfaces and Advanced Materials, Faculty of Sciences of Monastir, University of Monastir, Monastir 5000, Tunisia., Souid G; Research Unit: Viral Genomic and Antiviral Strategy (UR 17ES 30), University of Monastir, Higher Institute of Biotechnology of Monastir, Monastir 5000, Tunisia., Alminderej FM; Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi Arabia., Mzoughi Z; Laboratory of Interfaces and Advanced Materials, Faculty of Sciences of Monastir, University of Monastir, Monastir 5000, Tunisia., El-Ghoul Y; Department of Chemistry, College of Science, Qassim University, Buraidah 51452, Saudi Arabia.; Textile Engineering Laboratory, University of Monastir, Monastir 5019, Tunisia., Rihouey C; Normandie University, UNIROUEN, INSA Rouen, CNRS, PBS, UMR 6270 & FR 3038, 76000 Rouen, France., Le Cerf D; Normandie University, UNIROUEN, INSA Rouen, CNRS, PBS, UMR 6270 & FR 3038, 76000 Rouen, France., Majdoub H; Laboratory of Interfaces and Advanced Materials, Faculty of Sciences of Monastir, University of Monastir, Monastir 5000, Tunisia.
المصدر: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Feb 10; Vol. 12 (2). Date of Electronic Publication: 2023 Feb 10.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101668981 Publication Model: Electronic Cited Medium: Print ISSN: 2076-3921 (Print) Linking ISSN: 20763921 NLM ISO Abbreviation: Antioxidants (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2012]-
مستخلص: Coriandrum sativum is one of the most widespread curative plants in the world, being vastly cultivated in arid and semi-arid regions as one of the oldest spice plants. The present study explored the extraction of polysaccharides from Coriandrum sativum seeds and the evaluation of their antioxidant potential and hepatoprotective effects in vivo. The polysaccharide from coriander seeds was extracted, and the structural characterization was performed by FT-IR, UV-vis, DSC, NMR (1D and 2D), GC-MS, and SEC analysis. The polysaccharide extracted from Coriandrum sativum (CPS) seeds was characterized to evaluate its antioxidant and hepatoprotective capacities in rats. Results showed that CPS was composed of arabinose, rhamnose, xylose, mannose, fructose, galactose, and glucose in molar percentages of 6.2%, 3.6%, 8.8%, 17.7%, 5.2%, 32.9%, and 25.6%, respectively. Further, CPS significantly hindered cadmium-induced oxidation damage and exercised a protective effect against Cd hepatocytotoxicity, with a considerable reduction in MDA production and interesting CAT and SOD enzyme levels. Results suggest that CPS might be employed as a natural antioxidant source.
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فهرسة مساهمة: Keywords: Coriandrum sativum; antioxidants; hepatocytotoxicity; physicochemical characterizations; polysaccharide
تواريخ الأحداث: Date Created: 20230225 Latest Revision: 20230228
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC9952120
DOI: 10.3390/antiox12020455
PMID: 36830010
قاعدة البيانات: MEDLINE
الوصف
تدمد:2076-3921
DOI:10.3390/antiox12020455