دورية أكاديمية
Echocardiographic Left Ventricular Hypertrophy and Geometric Patterns in Patients with Sickle Cell Anaemia.
| العنوان: | Echocardiographic Left Ventricular Hypertrophy and Geometric Patterns in Patients with Sickle Cell Anaemia. |
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| المؤلفون: | Abba AM; Department of Haematology and Blood Transfusion, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria. Email: aisha.aseptic.mohammed06@gmail.com.; Department of Haematology and Blood Transfusion, Faculty of Basic Clinical Sciences, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria., Ladu AI; Department of Haematology and Blood Transfusion, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria. Email: aisha.aseptic.mohammed06@gmail.com.; Department of Haematology and Blood Transfusion, Faculty of Basic Clinical Sciences, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria., Bukar AA; Department of Haematology and Blood Transfusion, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria. Email: aisha.aseptic.mohammed06@gmail.com.; Department of Haematology and Blood Transfusion, Faculty of Basic Clinical Sciences, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria., Sulaiman MM; Nephrology Unit, Department of Medicine, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria.; Department of Medicine, Faculty of Clinical Sciences, College of Medical Sciences, University of Maiduguri, Nigeria., Abjah UM; Department of Haematology and Blood Transfusion, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria. Email: aisha.aseptic.mohammed06@gmail.com.; Department of Haematology and Blood Transfusion, Faculty of Basic Clinical Sciences, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria., Talle MA; Department of Medicine, Faculty of Clinical Sciences, College of Medical Sciences, University of Maiduguri, Nigeria.; Cardiology Unit, Department of Medicine, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria. |
| المصدر: | West African journal of medicine [West Afr J Med] 2023 Feb 28; Vol. 40 (2), pp. 137-142. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: West African College Of Physicians And West African College Of Surgeons Country of Publication: Nigeria NLM ID: 8301891 Publication Model: Print Cited Medium: Print ISSN: 0189-160X (Print) Linking ISSN: 0189160X NLM ISO Abbreviation: West Afr J Med Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Lagos : West African College Of Physicians And West African College Of Surgeons Original Publication: [Yaba, Lagos, Nigeria] : West African College of Physicians and West African College of Surgeons, [1981- |
| مواضيع طبية MeSH: | Hypertrophy, Left Ventricular* , Anemia, Sickle Cell*, Female ; Male ; Humans ; Echocardiography |
| مستخلص: | Background: Left ventricular hypertrophy (LVH) is a common complication in patients with sickle cell anaemia (SCA), and it has been associated with systolic and diastolic dysfunction, and sudden death. There is a wide variation in the reported prevalence of LVH in patients with SCA, partly due to the varying criteria applied, and the impact of small weight and body surface area (BSA) in SCA patients. We used four different criteria to determine echocardiographic LVH and geometric patterns in patients with steady-state SCA. Left ventricular hypertrophy was defined by LVM, LVM indexed to BSA, LVM indexed to height and LVM indexed to height2.7 using gender-specific reference values. Left ventricular geometry was determined using LVH and relative wall thickness. Results: Eighty-two patients with steady-state SCA, aged 18years and above were studied from January 2018 to April 2018. The median [IQR] age of the patients was 23 [10] years. Forty-seven (57.3%) were females. The prevalence of LVH was highest when LVM was indexed to BSA (80.5%), followed by LVM indexed to height (73.2%). Comparable prevalences of 68.3% and 69.5% were observed using LVM and LVM indexed to height2.7, respectively. The prevalence of LVH was similar in males and females for all the criteria. Conclusion: The prevalence of LVH is high among patients with steady-state SCA irrespective of the criteria applied. The most prevalent geometric pattern was eccentric LVH. Indexing to BSA might result in over-estimation of LVH given the relatively small BSA in patients with SCA. Indexing to height 2.7 might give a more accurate estimate of LVH. Competing Interests: The Authors declare that no competing interest exists. (Copyright © 2023 by West African Journal of Medicine.) |
| فهرسة مساهمة: | Keywords: Echocardiography; Left ventricular geometry; Left ventricular hypertrophy; Sickle cell disease Local Abstract: [Publisher, French] L’hypertrophie ventriculaire gauche (HVG) est une complication fréquente chez les patients atteints d’anémie falciforme (ACS), et elle a été associée à un dysfonctionnement systolique et diastolique, ainsi qu’à une mort subite. La prévalence de l’HVG chez les patients atteints d’anémie falciforme varie considérablement, en partie à cause des différents critères appliqués et de l’impact du petit poids et de la surface corporelle (BSA) des patients atteints d’anémie falciforme. Nous avons utilisé quatre critères différents pour déterminer l’HVG échocardiographique et les schémas géométriques chez les patients atteints d’ACS à l’état stable. L’hypertrophie ventriculaire gauche a été définie par la MVL, la MVL indexée sur la surface corporelle, la MVL indexée sur la taille et la MVL indexée sur la taille2,7 en utilisant des valeurs de référence spécifiques au sexe. La géométrie du ventricule gauche a été déterminée en utilisant l’HVG et l’épaisseur relative de la paroi. [Publisher, French] Quatre-vingts deux patients atteints d’ACS à l’état stable, âgés de 18 ans et plus ont été étudiés de janvier 2018 à avril 2018. L’âge médian [IQR] des patients était de 23 [10] ans. Quarantesept (57,3 %) étaient des femmes. La prévalence de l’HVG était la plus élevée lorsque la MVL était indexée sur la BSA (80,5 %), suivie de la MVL indexée sur la taille (73,2 %). Une prévalence comparable de 68,3 % et 69,5 % a été observée en utilisant la MVL et la MVL indexée sur la taille2,7, respectivement. La prévalence de l’HVG est similaire chez les hommes et les femmes pour tous les critères. [Publisher, French] La prévalence de l’HVG est élevée chez les patients atteints d’ACS à l’état stable, quel que soit le critère appliqué. Le modèle géométrique le plus répandu est l’HVG excentrique. L’indexation à la BSA pourrait entraîner une surestimation de l’HVG étant donné la BSA relativement faible chez les patients atteints d’ACS. L’indexation à la taille 2,7 pourrait donner une estimation plus précise de l’HVG. [Publisher, French] Hypertrophie ventriculaire gauche; Géométrie ventriculaire gauche; Drépanocytose ; Échocardiographie. |
| تواريخ الأحداث: | Date Created: 20230301 Date Completed: 20230303 Latest Revision: 20230303 |
| رمز التحديث: | 20240829 |
| PMID: | 36857485 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0189-160X |
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