دورية أكاديمية
أعرض في EDS

Effects of atropine and tropicamide on ocular biological parameters in children: a prospective observational study.

التفاصيل البيبلوغرافية
العنوان: Effects of atropine and tropicamide on ocular biological parameters in children: a prospective observational study.
المؤلفون: Tao Y; Department of Ophthalmology, Jiujiang No 1 Peoples Hospital, Affiliated Jiujiang Hospital of Nanchang University, 48 South Taling Road, Jiujiang, 332000, Jiangxi, China.; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Center of National Ocular Disease Clinical Research Center, 17 Yongwai Main Street, Nanchang, 330006, Jiangxi, China., Li M; Department of Ophthalmology, The Second Hospital of Anhui Medical University, No.678 Furong Road, Economic Development Zone, Hefei, 230031, Anhui, China., Tan J; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Center of National Ocular Disease Clinical Research Center, 17 Yongwai Main Street, Nanchang, 330006, Jiangxi, China., Huang J; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Center of National Ocular Disease Clinical Research Center, 17 Yongwai Main Street, Nanchang, 330006, Jiangxi, China., Cheng X; Department of Ophthalmology, Jiujiang No 1 Peoples Hospital, Affiliated Jiujiang Hospital of Nanchang University, 48 South Taling Road, Jiujiang, 332000, Jiangxi, China., Xie P; Department of Ophthalmology, Jiujiang No 1 Peoples Hospital, Affiliated Jiujiang Hospital of Nanchang University, 48 South Taling Road, Jiujiang, 332000, Jiangxi, China., Liu X; Department of Ophthalmology, Jiujiang No 1 Peoples Hospital, Affiliated Jiujiang Hospital of Nanchang University, 48 South Taling Road, Jiujiang, 332000, Jiangxi, China., Zhou Q; Department of Ophthalmology, The First Affiliated Hospital of Nanchang University, Jiangxi Center of National Ocular Disease Clinical Research Center, 17 Yongwai Main Street, Nanchang, 330006, Jiangxi, China. qiongzd06@126.com., Ouyang J; Department of Ophthalmology, Jiujiang No 1 Peoples Hospital, Affiliated Jiujiang Hospital of Nanchang University, 48 South Taling Road, Jiujiang, 332000, Jiangxi, China. 504219135@qq.com.
المصدر: BMC ophthalmology [BMC Ophthalmol] 2023 Mar 13; Vol. 23 (1), pp. 96. Date of Electronic Publication: 2023 Mar 13.
نوع المنشور: Observational Study; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967802 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2415 (Electronic) Linking ISSN: 14712415 NLM ISO Abbreviation: BMC Ophthalmol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central, [2001-
مواضيع طبية MeSH: Tropicamide*/pharmacology , Presbyopia*, Humans ; Child ; Child, Preschool ; Adolescent ; Atropine/pharmacology ; Mydriatics/pharmacology ; Refraction, Ocular ; Ciliary Body
مستخلص: Background: The effectiveness of cycloplegia in delaying the progression of myopia and its application in refractive examination in children have been extensively studied, but there are still few studies on the effects of atropine/tropicamide on ocular biological parameters. Therefore, the purpose of this study was to explore the effects of atropine/tropicamide on children's ocular biological parameters in different age groups and the differences between them.
Methods: This was a prospective observational study in which all school children were examined for dioptres and ocular biological parameters in the outpatient clinic, and 1% atropine or tropicamide was used for treatment. After examination, we enrolled the patients grouped by age (age from 2 to 12 years treated by atropine, 55 cases; age from 2 to 10 years treated by tropicamide, 70 cases; age from 14 to 17 years treated by tropicamide, 70 cases). The ocular biological parameters of each patient before and after cycloplegia were measured, and the difference and its absolute value were calculated for statistical analysis using an independent-samples t test.
Results: We compared the value and the absolute value of the differences in ocular biological parameters before and after cycloplegia in the same age group, and we found that the differences were not statistically significant (P > 0.05). There were significant differences in the corresponding values of AL, K1 and ACD among the different age groups (P < 0.05). Before cycloplegia, there were significant differences in AL, K, K1, K2 and ACD in different age groups (P < 0.05). However, the differences in AL, K, K1, K2 and ACD among different age groups disappeared after cycloplegia (P > 0.05).
Conclusions: This study demonstrated that atropine/tropicamide have different effects on cycloplegia in children of different ages. The effects of atropine/tropicamide on ocular biological parameters should be fully considered when evaluating the refractive state before refractive surgery or mydriasis optometry for children of different ages.
(© 2023. The Author(s).)
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معلومات مُعتمدة: 202140286 the Science and Technology Plan Project of the Health Commission of Jiangxi Province; 202140286 the Science and Technology Plan Project of the Health Commission of Jiangxi Province; 2021A151 the Science and Technology Program of Administration of traditional Chinese Medicine of Jiangxi Province; 2021A151 the Science and Technology Program of Administration of traditional Chinese Medicine of Jiangxi Province; 2021A151 the Science and Technology Program of Administration of traditional Chinese Medicine of Jiangxi Province; 005062833097 the General Project of the Key R & D Program of the Department of Science and Technology of Jiangxi Province; 005062833097 the General Project of the Key R & D Program of the Department of Science and Technology of Jiangxi Province; 005062833097 the General Project of the Key R & D Program of the Department of Science and Technology of Jiangxi Province; 005062833097 the General Project of the Key R & D Program of the Department of Science and Technology of Jiangxi Province
فهرسة مساهمة: Keywords: Atropine; Children; Cycloplegia; Ocular biometry; Tropicamide
المشرفين على المادة: N0A3Z5XTC6 (Tropicamide)
7C0697DR9I (Atropine)
0 (Mydriatics)
تواريخ الأحداث: Date Created: 20230314 Date Completed: 20230315 Latest Revision: 20230317
رمز التحديث: 20230320
مُعرف محوري في PubMed: PMC10010000
DOI: 10.1186/s12886-023-02840-5
PMID: 36915059
قاعدة البيانات: MEDLINE
الوصف
تدمد:1471-2415
DOI:10.1186/s12886-023-02840-5