التفاصيل البيبلوغرافية
| العنوان: |
Reassignment of NMR spectroscopic data of oleana-9(11),12-diene-3 β -ol isolated from Jeffreycia zeylanica and its wound healing potential in terms of cell migration and proangiogenic activity 1 . |
| المؤلفون: |
Samarasinghe WMP; Department of Chemistry, The Open University of Sri Lanka, Nugegoda, Sri Lanka., Gunaherath GMKB; Department of Chemistry, The Open University of Sri Lanka, Nugegoda, Sri Lanka., Ranasinghe C; Department of Chemistry, The Open University of Sri Lanka, Nugegoda, Sri Lanka., Jayawardana KH; Department of Zoology, The Open University of Sri Lanka, Nugegoda, Sri Lanka. |
| المصدر: |
Natural product research [Nat Prod Res] 2024 Aug; Vol. 38 (15), pp. 2577-2584. Date of Electronic Publication: 2023 Mar 20. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
| مواضيع طبية MeSH: |
Magnetic Resonance Spectroscopy*/methods , Wound Healing*/drug effects , Cell Movement*/drug effects , Asteraceae*/chemistry, Molecular Structure ; Animals ; Humans ; Sri Lanka ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Chorioallantoic Membrane/drug effects |
| مستخلص: |
Jeffreycia zeylanica (Asteraceae), a plant endemic to Sri Lanka, is used for the treatment of wounds. The scratch wound assay (SWA) guided fractionation of hexanes extract of J. zeylanica led to the isolation of oleana-9(11),12-diene-3 β -ol ( 1 ) which showed enhanced cell migration in SWA and significant proangiogenic response in chorioallantoic membrane (CAM) assay. Since the reported 1 H NMR assignments of 1 were incomplete, and some 13 C NMR assignments were inconsistent with our observations, reassignment of NMR spectroscopic data of 1 was carried out. Herein we report unambiguous assignment of NMR data of 1 based on 1D and 2D NMR spectra. This is the first report of 1 in J. zeylanica . |
| فهرسة مساهمة: |
Keywords: ),12-diene-3β-ol; 1D and 2D NMR spectroscopy; Asteraceae; Jeffreycia zeylanica; chorioallantoic membrane (CAM) assay; oleana-9(11; scratch wound assay (SWA) |
| المشرفين على المادة: |
0 (Plant Extracts) |
| تواريخ الأحداث: |
Date Created: 20230320 Date Completed: 20240715 Latest Revision: 20240715 |
| رمز التحديث: |
20240716 |
| DOI: |
10.1080/14786419.2023.2190112 |
| PMID: |
36938871 |
| قاعدة البيانات: |
MEDLINE |
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