دورية أكاديمية
أعرض في EDS

Vector competence of sterile male Glossina fuscipes fuscipes for Trypanosoma brucei brucei: implications for the implementation of the sterile insect technique in a sleeping sickness focus in Chad.

التفاصيل البيبلوغرافية
العنوان: Vector competence of sterile male Glossina fuscipes fuscipes for Trypanosoma brucei brucei: implications for the implementation of the sterile insect technique in a sleeping sickness focus in Chad.
المؤلفون: Mahamat MH; Institut de Recherche en Elevage pour le Développement (IRED), Ndjaména, Chad., Ségard A; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France., Rayaisse JB; Centre International de Recherche-Développement sur l'Elevage en Zone Subhumide (CIRDES), Bobo-Dioulasso, Burkina Faso., Argiles-Herrero R; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria., Parker AG; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria., Solano P; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France., Abd-Alla AMM; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria., Bouyer J; Joint Food and Agriculture Organization of the United Nations/International Atomic Energy Agency Centre of Nuclear Techniques in Food and Agriculture, Insect Pest Control Sub-programme, A-1400, Vienna, Austria.; Université de Montpellier, Cirad, INRAE, ASTRE, Montpellier, France., Ravel S; Université de Montpellier, Cirad, IRD, Intertryp, Montpellier, France. sophie.ravel@ird.fr.
المصدر: Parasites & vectors [Parasit Vectors] 2023 Mar 22; Vol. 16 (1), pp. 111. Date of Electronic Publication: 2023 Mar 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101462774 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-3305 (Electronic) Linking ISSN: 17563305 NLM ISO Abbreviation: Parasit Vectors Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London : BioMed Central
مواضيع طبية MeSH: Trypanosomiasis, African*/epidemiology , Trypanosomiasis, African*/prevention & control , Trypanosomiasis, African*/parasitology , Tsetse Flies*/parasitology , Trypanosoma brucei brucei* , Trypanocidal Agents* , Trypanosoma* , Infertility, Male*, Animals ; Male ; Humans ; Chad/epidemiology ; Insecta
مستخلص: Background: Human African trypanosomiasis (HAT) is a neglected tropical disease caused by Trypanosoma brucei gambiense transmitted by tsetse flies in sub-Saharan West Africa. In southern Chad the most active and persistent focus is the Mandoul focus, with 98% of the reported human cases, and where African animal trypanosomosis (AAT) is also present. Recently, a control project to eliminate tsetse flies (Glossina fuscipes fuscipes) in this focus using the sterile insect technique (SIT) was initiated. However, the release of large numbers of sterile males of G. f. fuscipes might result in a potential temporary increase in transmission of trypanosomes since male tsetse flies are also able to transmit the parasite. The objective of this work was therefore to experimentally assess the vector competence of sterile males treated with isometamidium for Trypanosoma brucei brucei.
Methods: An experimental infection was set up in the laboratory, mimicking field conditions: the same tsetse species that is present in Mandoul was used. A T. b. brucei strain close to T. b. gambiense was used, and the ability of the sterile male tsetse flies fed on blood with and without a trypanocide to acquire and transmit trypanosomes was measured.
Results: Only 2% of the experimentally infected flies developed an immature infection (midgut) while none of the flies developed a metacyclic infection of T. b. brucei in the salivary glands. We did not observe any effect of the trypanocide used (isometamidium chloride at 100 mg/l) on the development of infection in the flies.
Conclusions: Our results indicate that sterile males of the tested strain of G. f. fuscipes were unable to cyclically transmit T. b. brucei and might even be refractory to the infection. The data of the research indicate that the risk of cyclical transmission of T. brucei by sterile male G. f. fuscipes of the strain colonized at IAEA for almost 40 years appears to be small.
(© 2023. The Author(s).)
References: Exp Parasitol. 1976 Dec;40(3):427-31. (PMID: 976425)
Acta Trop. 2003 Oct;88(2):161-5. (PMID: 14516928)
Rev Elev Med Vet Pays Trop. 1968;21(4):479-91. (PMID: 5713829)
Biochem J. 1997 Sep 15;326 ( Pt 3):755-61. (PMID: 9307025)
Biochem J. 1995 Nov 15;312 ( Pt 1):319-27. (PMID: 7492332)
Parasit Vectors. 2015 May 01;8:259. (PMID: 25927610)
Med Trop (Mars). 2009 Feb;69(1):7-12. (PMID: 19499723)
Nat Commun. 2020 Mar 12;11(1):1326. (PMID: 32165615)
PLoS Negl Trop Dis. 2021 Jun 9;15(6):e0009323. (PMID: 34106914)
Ann Trop Med Parasitol. 1963 Sep;57:255-61. (PMID: 14077658)
Parasitology. 2004 Dec;129(Pt 6):693-702. (PMID: 15648692)
Int J Radiat Biol. 1996 Jan;69(1):67-74. (PMID: 8601757)
J Med Entomol. 2006 May;43(3):564-7. (PMID: 16739416)
BMC Genomics. 2016 Nov 25;17(1):971. (PMID: 27884110)
Acta Trop. 1987 Mar;44(1):23-8. (PMID: 2884836)
PLoS Negl Trop Dis. 2017 Jul 27;11(7):e0005792. (PMID: 28750007)
Adv Parasitol. 1980;18:175-246. (PMID: 7001872)
Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10149-54. (PMID: 24982143)
Med Vet Entomol. 2008 Jun;22(2):140-3. (PMID: 18498613)
PLoS One. 2019 May 14;14(5):e0216802. (PMID: 31086401)
J Econ Entomol. 2000 Feb;93(1):123-35. (PMID: 14658522)
Med Vet Entomol. 2006 Dec;20(4):388-92. (PMID: 17199750)
Bull Soc Pathol Exot. 1994;87(5):391-3. (PMID: 7496207)
PLoS Negl Trop Dis. 2020 May 21;14(5):e0008261. (PMID: 32437391)
Parasit Vectors. 2008 Mar 14;1(1):5. (PMID: 18341697)
Proc Natl Acad Sci U S A. 1990 Feb;87(3):950-4. (PMID: 2153980)
Trans R Soc Trop Med Hyg. 1992 Jul-Aug;86(4):394-5. (PMID: 1440814)
معلومات مُعتمدة: EVT 1804311 IAEA
فهرسة مساهمة: Keywords: Isometamidium; Trypanocide; Trypanosoma brucei gambiense; Tsetse
المشرفين على المادة: 0 (Trypanocidal Agents)
تواريخ الأحداث: Date Created: 20230323 Date Completed: 20230324 Latest Revision: 20230328
رمز التحديث: 20240829
مُعرف محوري في PubMed: PMC10035118
DOI: 10.1186/s13071-023-05721-4
PMID: 36949538
قاعدة البيانات: MEDLINE
الوصف
تدمد:1756-3305
DOI:10.1186/s13071-023-05721-4