دورية أكاديمية
Factors associated with poor treatment outcomes among tuberculosis patients in Kyangwali Refugee Settlement, Uganda, 2016-2017.
| العنوان: | Factors associated with poor treatment outcomes among tuberculosis patients in Kyangwali Refugee Settlement, Uganda, 2016-2017. |
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| المؤلفون: | Nguna J; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda., Okethwangu D; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda., Kabwama SN; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda., Aliddeki DM; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda., Kironde SK; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda., Birungi D; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda., Eurien D; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda., Ario AR; Uganda Public Health Fellowship Program, Ministry of Health, Kampala, Uganda.; Ministry of Health, Kampala, Uganda., Lukoye D; Ministry of Health, Kampala, Uganda., Kasozi J; United Nations High Commission for Refugees, Kampala, Uganda., Cegielski PJ; Division of Global HIV and TB, Global TB Branch, US Centers for Diseases Control and Prevention, Atlanta, Georgia, United States of America. |
| المصدر: | PLOS global public health [PLOS Glob Public Health] 2022 Aug 02; Vol. 2 (8), pp. e0000152. Date of Electronic Publication: 2022 Aug 02 (Print Publication: 2022). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 9918283779606676 Publication Model: eCollection Cited Medium: Internet ISSN: 2767-3375 (Electronic) Linking ISSN: 27673375 NLM ISO Abbreviation: PLOS Glob Public Health Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: San Francisco, California : Public Library of Science, [2021]- |
| مستخلص: | Communicable diseases, alone or in combination with malnutrition, account for most deaths in complex emergencies including refugee settings. Tuberculosis and HIV/AIDS are increasingly becoming an important cause of morbidity and mortality in refugee settings. We described the treatment outcomes of TB patients and explored factors associated with treatment outcomes among TB patients attending two facilities in Kyangwali Refugee Settlement in Kikuube District, 2016-2017. We abstracted data on laboratory-confirmed patient data from TB registers from 2016 to 2017, in Kikuube Health Centre IV and Rwenyawawa Health Centre II, both located in Kyangwali Refugee Settlement. We abstracted data on socio-demographic variables including age and sex. Other variables were height, weight, final treatment outcomes, demographics, HIV status, TB treatment category, and history of TB. Treatment outcomes were categorized into favorable (including patients who were cured or those who completed treatment) and unfavorable (those in whom treatment failed, those who died, those lost to follow-up, or those not evaluated). We used logistic regression to identify factors associated with unfavorable treatment outcomes. We identified a total of 254 TB patients with a median age of 36 (IQR 26-48) years; 69% (175) were male and 54% (137) were refugees. The median weight was 50.4 kg (range 4-198). Overall, 139 (55%) had favorable outcomes while 115 (45%) had unfavorable outcomes. Refugees formed 53% (71) of those with favorable outcomes and 47% (63) of those with unfavorable outcomes 63(47%). We found that increasing age was statistically associated with unfavorable outcomes, while diagnosis with MDR-TB was associated with decreased odds for unfavorable treatment outcomes. The treatment success rate was lower compared to 85% recommended by WHO. However, the rates are similar to that reported by other studies in Uganda. Innovative approaches to improve treatment success rates with particular focus on persons aged 41-80 years should be devised. Competing Interests: The authors have declared that no competing interests exist. (Copyright: © 2022 Nguna et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.) |
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| تواريخ الأحداث: | Date Created: 20230324 Latest Revision: 20230327 |
| رمز التحديث: | 20230327 |
| مُعرف محوري في PubMed: | PMC10022256 |
| DOI: | 10.1371/journal.pgph.0000152 |
| PMID: | 36962487 |
| قاعدة البيانات: | MEDLINE |
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