Impact of Mesoporous Silica Functionalization Fine-Tuning on Antibiotic Uptake/Delivery and Bactericidal Activity.

التفاصيل البيبلوغرافية
العنوان:	Impact of Mesoporous Silica Functionalization Fine-Tuning on Antibiotic Uptake/Delivery and Bactericidal Activity.
المؤلفون:	Bouchmella K; Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), P.O. Box 6192, Campinas CEP 13083-970, SP, Brazil.; Chemistry Institute (IQ), Universidade Estadual de Campinas (UNICAMP), P.O. Box 6154, Campinas CEP 13083-970, SP, Brazil.; ICGM, University Montpellier, CNRS, ENSCM, 34095 Montpellier, France., Lion Q; Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), P.O. Box 6192, Campinas CEP 13083-970, SP, Brazil.; Interdisciplinary Cluster for Applied Genoproteomics, University of Liege, Liege 4000, Belgium.; Laboratory of Medical Chemistry, University of Liege, Liege 4000, Belgium.; GIGA Stem Cells, University of Liege, Liege 4000, Belgium., Gervais C; LCMCP - Laboratoire de Chimie de la Matière Condensée de Paris, Sorbonne Université, 4 place Jussieu, 75252 Paris Cedex 05, France., Cardoso MB; Brazilian Synchrotron Light Laboratory (LNLS), Brazilian Center for Research in Energy and Materials (CNPEM), P.O. Box 6192, Campinas CEP 13083-970, SP, Brazil.; Chemistry Institute (IQ), Universidade Estadual de Campinas (UNICAMP), P.O. Box 6154, Campinas CEP 13083-970, SP, Brazil.
المصدر:	ACS omega [ACS Omega] 2023 Mar 22; Vol. 8 (13), pp. 12154-12164. Date of Electronic Publication: 2023 Mar 22 (Print Publication: 2023).
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE
أسماء مطبوعة:	Original Publication: Washington, D.C. : American Chemical Society, [2016]-
مستخلص:	The mesoporous SBA-15 material was surface-functionalized with amino and carboxylic acid groups and used as a platform to investigate the interaction of these chemical groups with tetracycline, kanamycin, and ampicillin antibiotics. The interactions between the antibiotic and the functionalized surfaces were characterized using two-dimensional ¹ H- ¹³ C HETCOR CP MAS and FTIR spectroscopy and indicated that -COO ^- NH 3 ⁺ bondings had been formed between chemical groups on the silica surface and drug molecules. The surface modification resulted in higher kanamycin and ampicillin loadings and a slow-release rate, and all synthesized systems showed antibacterial activity against susceptible Escherichia coli bacteria. Almost total death of bacteria was obtained using a few ppm of tetracycline- and kanamycin-loaded systems, whereas the ampicillin-loaded one showed lower bactericidal activity than free ampicillin. Competing Interests: The authors declare no competing financial interest. (© 2023 The Authors. Published by American Chemical Society.)
References:	J Colloid Interface Sci. 2015 Apr 1;443:105-14. (PMID: 25540827) J Magn Reson. 1998 Nov;135(1):144-55. (PMID: 9799688) Nat Rev Drug Discov. 2011 Jul 01;10(7):521-35. (PMID: 21720407) J Phys Chem B. 2006 Aug 10;110(31):15157-65. (PMID: 16884230) Phys Rev B Condens Matter. 1991 Jan 15;43(3):1993-2006. (PMID: 9997467) J Colloid Interface Sci. 2011 Feb 1;354(1):261-7. (PMID: 21130463) J Am Chem Soc. 1975 Oct 15;97(21):6245-8. (PMID: 1176731) Phys Rev Lett. 1996 Oct 28;77(18):3865-3868. (PMID: 10062328) J Phys Condens Matter. 2009 Sep 30;21(39):395502. (PMID: 21832390) Prog Nucl Magn Reson Spectrosc. 2014 Feb;77:1-48. (PMID: 24411829) Nanomedicine (Lond). 2018 Jul 1;13(14):1731-1751. (PMID: 30074435) Anal Bioanal Chem. 2011 Mar;399(7):2503-9. (PMID: 21243340) Angew Chem Int Ed Engl. 2007;46(40):7548-58. (PMID: 17854012) J Phys Chem B. 2005 Sep 8;109(35):16725-9. (PMID: 16853129) Small. 2019 Jun;15(24):e1900669. (PMID: 31033214) Chem Soc Rev. 2012 Apr 7;41(7):2590-605. (PMID: 22216418) Chem Commun (Camb). 2011 Sep 28;47(36):9972-85. (PMID: 21716992) J Am Chem Soc. 2006 Dec 20;128(50):16266-76. (PMID: 17165781) Molecules. 2015 Oct 30;20(11):19690-8. (PMID: 26528964) Int J Nanomedicine. 2013;8:4015-31. (PMID: 24174875) Molecules. 2020 Aug 21;25(17):. (PMID: 32825791) Chem Eng J. 2013 May 1;223(100):678-687. (PMID: 24976787)
تواريخ الأحداث:	Date Created: 20230410 Latest Revision: 20230411
رمز التحديث:	20230411
مُعرف محوري في PubMed:	PMC10077561
DOI:	10.1021/acsomega.2c08065
PMID:	37033793
قاعدة البيانات:	MEDLINE

Find this issue from the American Chemical Society

Full Text Finder

الوصف
تدمد:	2470-1343
DOI:	10.1021/acsomega.2c08065