تقرير
Hepatocellular Carcinoma Metastasis to the Tonsil: A Case Report of a Rare Entity.
| العنوان: | Hepatocellular Carcinoma Metastasis to the Tonsil: A Case Report of a Rare Entity. |
|---|---|
| المؤلفون: | Karamitsou P; Department of Otorhinolaryngology - Head and Neck Surgery, 'G. Papanikolaou' General Hospital, Thessaloniki, GRC., Skliris JP; Department of Pathology, 'G. Papanikolaou' General Hospital, Thessaloniki, GRC., Gougousis S; Department of Otorhinolaryngology - Head and Neck Surgery, 'G. Papanikolaou' General Hospital, Thessaloniki, GRC., Karamitsou A; Fourth Department of Surgery, School of Medicine, Aristotle University of Thessaloniki, 'G. Papanikolaou' General Hospital, Thessaloniki, GRC., Poutoglidis A; Department of Otorhinolaryngology - Head and Neck Surgery, 'G. Papanikolaou' General Hospital, Thessaloniki, GRC. |
| المصدر: | Cureus [Cureus] 2023 Mar 09; Vol. 15 (3), pp. e35943. Date of Electronic Publication: 2023 Mar 09 (Print Publication: 2023). |
| نوع المنشور: | Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Cureus, Inc Country of Publication: United States NLM ID: 101596737 Publication Model: eCollection Cited Medium: Print ISSN: 2168-8184 (Print) Linking ISSN: 21688184 NLM ISO Abbreviation: Cureus Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: Palo Alto, CA : Cureus, Inc. |
| مستخلص: | Hepatocellular carcinoma (HCC) is the most dominant malignant neoplasm of the liver and constitutes the majority of all primary malignancies. Most reported cases of HCC occur in the developing world and are mainly associated with chronic hepatitis B and C viruses. Both hematogenous and lymphatic spreading is common in HCC. Patients with HCC might manifest extra-hepatic metastases and the lungs are the most common potential site of metastatic deposits. Rare sites of metastatic disease have also been described. Oropharyngeal metastases of HCC are rare and there are few reports available in the literature. We report a rare case of extra-hepatic metastasis of HCC to the right tonsil in an 84-year-old patient. The clinical appearance of metastatic oral lesions could be easily underestimated, and diagnosis of the primary tumor might delay. A biopsy of the oral lesion is important for an accurate diagnosis. Metastasis in the oral cavity and oropharynx of an HCC is usually evidence of widespread disease and predisposes to an ominous prognosis. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2023, Karamitsou et al.) |
| References: | Ann Hepatobiliary Pancreat Surg. 2020 Feb;24(1):68-71. (PMID: 32181432) J Periodontol. 1996 Jul;67(7):717-9. (PMID: 8832483) Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Mar;97(3):359-68. (PMID: 15024361) J Oral Maxillofac Surg. 1989 Sep;47(9):987-90. (PMID: 2668472) J Natl Compr Canc Netw. 2018 Jan;16(1):50-58. (PMID: 29295881) J Gastroenterol Hepatol. 2005 Nov;20(11):1781-7. (PMID: 16246200) Cancer. 1982 Jan 15;49(2):354-60. (PMID: 6172192) Oral Surg Oral Med Oral Pathol. 1993 Sep;76(3):368-74. (PMID: 8378053) Int J Cancer. 2015 Mar 1;136(5):E359-86. (PMID: 25220842) Clin Gastroenterol Hepatol. 2007 Aug;5(8):938-45, 945.e1-4. (PMID: 17509946) Ann Surg. 1940 Jul;112(1):138-49. (PMID: 17857618) J Oral Pathol Med. 1993 Oct;22(9):385-90. (PMID: 8301602) Oral Surg Oral Med Oral Pathol. 1965 Sep;20:350-62. (PMID: 14342927) J Natl Cancer Inst. 2017 Sep 1;109(9):. (PMID: 28376154) |
| فهرسة مساهمة: | Keywords: extra-hepatic metastasis; hepatocellular carcinoma; lesion; oropharynx; tonsil |
| تواريخ الأحداث: | Date Created: 20230411 Latest Revision: 20230412 |
| رمز التحديث: | 20240628 |
| مُعرف محوري في PubMed: | PMC10082621 |
| DOI: | 10.7759/cureus.35943 |
| PMID: | 37038565 |
| قاعدة البيانات: | MEDLINE |
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