دورية أكاديمية

Endemic melioidosis in central Taiwan-A longitudinal case cohort study.

التفاصيل البيبلوغرافية
العنوان: Endemic melioidosis in central Taiwan-A longitudinal case cohort study.
المؤلفون: Ling TT; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan., Lee SY; Infection Control Center, Chung Shan Medical University Hospital, Taichung, Taiwan., Tsao SM; Division of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.; School of Medicine, Chung Shan Medical University, Taichung, Taiwan., Liang KW; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Department of Medical Imaging, Chung Shan Medical University Hospital, Taichung, Taiwan., Wang WY; School of Medicine, Chung Shan Medical University, Taichung, Taiwan.; Division of Infectious Disease, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung, Taiwan.
المصدر: Frontiers in medicine [Front Med (Lausanne)] 2023 Apr 06; Vol. 10, pp. 1131788. Date of Electronic Publication: 2023 Apr 06 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Lausanne, Switzerland : Frontiers Media S.A., [2014]-
مستخلص: Background: Melioidosis is a systemic and suppurative disease endemic in the Southeast Asia. In Taiwan, most cases are reported in the southern region and no relevant profiles have been reported in central region. In this study, we performed the epidemiologic and clinical analyses from the melioidosis cases in central Taiwan.
Methods: The demographic, clinical, laboratory, radiologic, and outcome profiles were collected retrospectively and analyzed from patients whom Burkhoderia pseudomallei was isolated from clinical specimens during the 12-year study period (2011-2022).
Results: Totally 11 melioidosis cases (10 males and 1 female) were diagnosed, among them only 2 (18.2%) cases lived in suburban areas. Seven (63.6%) cases were diagnosed during 2019-2020, and diabetes mellitus was the most relevant comorbidity (5, 45.4%). All cases presented with fever at arrival, but only 4 (36.4%) and 2 (18.2%) cases presented with dyspnea and shock, respectively. Pneumonitis and extrapulmonary involvement were found in 5 cases (45.4%) each. Appropriate empiric and targeted antibiotic treatments were found in 4 (36.4%) and 10 (91.0%) case, respectively. Two cases (18.2%) succumbed to infection despite appropriate treatment including targeted antibiotics.
Conclusion: Melioidosis has become endemic in central Taiwan. Septic patients who present with suppurative or undetermined foci and have unsatisfied responses to standard treatment should arouse clinicians to take melioidosis into consideration.
Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
(Copyright © 2023 Ling, Lee, Tsao, Liang and Wang.)
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فهرسة مساهمة: Keywords: Burkhoderia pseudomallei; Outcome; antibiotic; melioidosis; suppurative
تواريخ الأحداث: Date Created: 20230424 Latest Revision: 20230425
رمز التحديث: 20230502
مُعرف محوري في PubMed: PMC10115954
DOI: 10.3389/fmed.2023.1131788
PMID: 37089599
قاعدة البيانات: MEDLINE