دورية أكاديمية

The sclerosing sertoli cell tumor of the testis: a case report.

التفاصيل البيبلوغرافية
العنوان: The sclerosing sertoli cell tumor of the testis: a case report.
المؤلفون: Tang X; Department of Ultrasound, The Third People's Hospital of Chengdu, Clinical College of Southwest Jiao Tong University, The Second Affiliated Chengdu Hospital of Chongqing Medical University, Chengdu, Sichuan, China., Hu Y; Department of Pathology, The Third People's Hospital of Chengdu, Clinical College of Southwest Jiao Tong University, The Second Affiliated Chengdu Hospital of Chongqing Medical University, Chengdu, Sichuan, China., Zhou H; Department of Ultrasound, The Third People's Hospital of Chengdu, Clinical College of Southwest Jiao Tong University, The Second Affiliated Chengdu Hospital of Chongqing Medical University, Chengdu, Sichuan, China., Zhou Y; Department of Ultrasound, The Third People's Hospital of Chengdu, Clinical College of Southwest Jiao Tong University, The Second Affiliated Chengdu Hospital of Chongqing Medical University, Chengdu, Sichuan, China. hansenzy@126.com.
المصدر: Diagnostic pathology [Diagn Pathol] 2023 May 15; Vol. 18 (1), pp. 61. Date of Electronic Publication: 2023 May 15.
نوع المنشور: Case Reports; Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101251558 Publication Model: Electronic Cited Medium: Internet ISSN: 1746-1596 (Electronic) Linking ISSN: 17461596 NLM ISO Abbreviation: Diagn Pathol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, 2006-
مواضيع طبية MeSH: Sertoli Cell Tumor*/diagnosis , Sertoli Cell Tumor*/surgery , Sertoli Cell Tumor*/pathology , Testicular Neoplasms*/diagnosis , Testicular Neoplasms*/surgery , Testicular Neoplasms*/pathology , Sex Cord-Gonadal Stromal Tumors*/diagnosis , Sex Cord-Gonadal Stromal Tumors*/surgery , Sex Cord-Gonadal Stromal Tumors*/pathology, Male ; Humans ; Middle Aged ; Testis/pathology ; Sertoli Cells/pathology
مستخلص: Background: Testicular Sertoli cell tumor (SCT) is very rare sex cord-gonadal stromal tumor, and sclerosing SCT (SSCT) is even rarer. So far, no more than 50 cases of SSCT have been reported. 80% of SSCTs are less than 2 cm in diameter, large volume mass is pretty unusual. SSCT is usually benign with very low malignant potential. However, it is easily misdiagnosed as a malignant tumor resulting in the removal of the entire testicle.
Case Presentation: A 55-year-old Chinese male patient presented with a six months' history of right testis progressively enlargement and negative tumor markers. The physical examination was nothing special except for swelling in the right testicle. Imaging identified a large mass in right testicle with rich blood. A right radical orchiectomy was performed on suspicion of malignancy. However, the tumor was postoperatively diagnosed as SSCT, which pathologically consisted of a tubular pattern with regular nuclei and embedded in a densely collagenous stroma, as well as diffusely positive for vimentin, β-catenin and synaptophysin. After 7 months of follow up, no evidence of local recurrence and metastasis has been observed.
Conclusion: This rare case is helpful to expand the knowledge of the testicular tumor and alert us fully understand the rare variant of SCTs in order to choose the optimal management when they encounter SSCT.
(© 2023. The Author(s).)
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فهرسة مساهمة: Keywords: Case report; Sclerosing sertoli cell tumor; Sertoli cell tumor; Testicular neoplasm
تواريخ الأحداث: Date Created: 20230515 Date Completed: 20230517 Latest Revision: 20230519
رمز التحديث: 20230519
مُعرف محوري في PubMed: PMC10186805
DOI: 10.1186/s13000-023-01351-7
PMID: 37189109
قاعدة البيانات: MEDLINE
الوصف
تدمد:1746-1596
DOI:10.1186/s13000-023-01351-7