دورية أكاديمية
The D 3 -creatine dilution method non-invasively measures muscle mass in mice.
| العنوان: | The D |
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| المؤلفون: | Wimer L; Buck Institute for Research on Aging, Novato, California, USA., Goncharova E; Buck Institute for Research on Aging, Novato, California, USA., Galkina S; Buck Institute for Research on Aging, Novato, California, USA., Nyangau E; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA., Shankaran M; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA., Davis A; Buck Institute for Research on Aging, Novato, California, USA., Prado L; Buck Institute for Research on Aging, Novato, California, USA., Munoz MC; Buck Institute for Research on Aging, Novato, California, USA., Epstein S; Buck Institute for Research on Aging, Novato, California, USA., Patterson C; Buck Institute for Research on Aging, Novato, California, USA., Shaum N; Astera Institute, Berkeley, California, USA., Hellerstein M; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA., Evans W; Department of Nutritional Sciences and Toxicology, University of California, Berkeley, California, USA., Melov S; Buck Institute for Research on Aging, Novato, California, USA. |
| المصدر: | Aging cell [Aging Cell] 2023 Aug; Vol. 22 (8), pp. e13897. Date of Electronic Publication: 2023 Jun 05. |
| نوع المنشور: | Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101130839 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-9726 (Electronic) Linking ISSN: 14749718 NLM ISO Abbreviation: Aging Cell Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford, UK : Wiley-Blackwell Original Publication: Oxford, UK : Blackwell Pub., c2002- |
| مواضيع طبية MeSH: | Body Composition* , Creatinine*/urine , Body Weights and Measures*/methods, Muscle, Skeletal ; Absorptiometry, Photon ; Animals ; Mice ; Male ; Female ; Mice, Inbred C57BL |
| مستخلص: | Developing accurate methods to quantify age-related muscle loss (sarcopenia) could greatly accelerate development of therapies to treat muscle loss in the elderly, as current methods are inaccurate or expensive. The current gold standard method for quantifying sarcopenia is dual-energy X-ray absorptiometry (DXA) but does not measure muscle directly-it is a composite measure quantifying "lean mass" (muscle) excluding fat and bone. In humans, DXA overestimates muscle mass, which has led to erroneous conclusions about the importance of skeletal muscle in human health and disease. In animal models, DXA is a popular method for measuring lean mass. However, instrumentation is expensive and is potentially limited by anesthesia concerns. Recently, the D (© 2023 The Authors. Aging Cell published by Anatomical Society and John Wiley & Sons Ltd.) |
| التعليقات: | Erratum in: Aging Cell. 2023 Dec;22(12):e13999. (PMID: 37781862) |
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| فهرسة مساهمة: | Keywords: aging; mice; sarcopenia; skeletal muscle |
| المشرفين على المادة: | AYI8EX34EU (Creatinine) |
| تواريخ الأحداث: | Date Created: 20230605 Date Completed: 20230810 Latest Revision: 20240404 |
| رمز التحديث: | 20240404 |
| مُعرف محوري في PubMed: | PMC10410001 |
| DOI: | 10.1111/acel.13897 |
| PMID: | 37272263 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1474-9726 |
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| DOI: | 10.1111/acel.13897 |