دورية أكاديمية
أعرض في EDS

Prognostic value of neutrophil and lymphocyte counts and neutrophil/lymphocyte ratio for predicting death in patients hospitalized for COVID-19.

التفاصيل البيبلوغرافية
العنوان: Prognostic value of neutrophil and lymphocyte counts and neutrophil/lymphocyte ratio for predicting death in patients hospitalized for COVID-19.
المؤلفون: Sejópoles MD; Julio Müller School Hospital, Federal University of Mato Grosso. Rua Dr Luis P Pereira Leite Sn, Cuiabá (MT), Brazil., Souza-Silva JP; Julio Müller School Hospital, Federal University of Mato Grosso. Rua Dr Luis P Pereira Leite Sn, Cuiabá (MT), Brazil.; Faculty of Medicine. Post-Graduation in Health Sciences, Federal University of Mato Grosso, Av Fernando Correa da Costa, 2367, Cuiabá (MT), Brazil., Silva-Santos C; Julio Müller School Hospital, Federal University of Mato Grosso. Rua Dr Luis P Pereira Leite Sn, Cuiabá (MT), Brazil.; Faculty of Medicine. Post-Graduation in Health Sciences, Federal University of Mato Grosso, Av Fernando Correa da Costa, 2367, Cuiabá (MT), Brazil., Paula-Duarte MM; Julio Müller School Hospital, Federal University of Mato Grosso. Rua Dr Luis P Pereira Leite Sn, Cuiabá (MT), Brazil.; Faculty of Medicine. Post-Graduation in Health Sciences, Federal University of Mato Grosso, Av Fernando Correa da Costa, 2367, Cuiabá (MT), Brazil., Fontes CJ; Julio Müller School Hospital, Federal University of Mato Grosso. Rua Dr Luis P Pereira Leite Sn, Cuiabá (MT), Brazil.; Faculty of Medicine. Post-Graduation in Health Sciences, Federal University of Mato Grosso, Av Fernando Correa da Costa, 2367, Cuiabá (MT), Brazil., Gomes LT; Julio Müller School Hospital, Federal University of Mato Grosso. Rua Dr Luis P Pereira Leite Sn, Cuiabá (MT), Brazil.; Faculty of Medicine. Post-Graduation in Health Sciences, Federal University of Mato Grosso, Av Fernando Correa da Costa, 2367, Cuiabá (MT), Brazil.
المصدر: Heliyon [Heliyon] 2023 Jun; Vol. 9 (6), pp. e16964. Date of Electronic Publication: 2023 Jun 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: London : Elsevier Ltd, [2015]-
مستخلص: COVID-19 primarily affects the respiratory system and can cause changes in other systems. Early identification of patients with a higher potential for complications is critical to provide the best possible treatment to reduce the disease's lethality. This study aimed to analyze the behavior of hematologic biomarkers in predicting mortality in patients hospitalized with COVID-19. This retrospective cohort study used data from the medical records of patients hospitalized with COVID-19 between March and August 2020 in two referral hospitals for treatment of the disease in the city of Cuiabá (in the state of Mato Grosso, Brazil). Clinical and laboratory characteristics related to cardiovascular involvement and death during hospitalization were evaluated. Neutrophils, lymphocytes, and monocytes, as well as the neutrophil-to-lymphocyte ratio (NLR) and the monocyte-to-lymphocyte ratio (MRL), were used as potential biomarkers of death. A total of 199 patients were included (male: 113; mean age: 51.4 years). Leukocyte, neutrophil, and lymphocyte counts showed a statistically significant association with death, as did NLR and MRL. Satisfactory accuracy in predicting death was observed for leukocyte, neutrophil, lymphocyte, NLR, and MLR counts. The hematologic biomarkers studied may be useful for prognosticating hospitalized patients for the possibility of death from COVID-19.
Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(© 2023 The Authors.)
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فهرسة مساهمة: Keywords: Biomarkers; COVID-19; Death; Lymphocyte; Monocyte; Neutrophil
تواريخ الأحداث: Date Created: 20230609 Latest Revision: 20230619
رمز التحديث: 20240628
مُعرف محوري في PubMed: PMC10238120
DOI: 10.1016/j.heliyon.2023.e16964
PMID: 37292322
قاعدة البيانات: MEDLINE
الوصف
تدمد:2405-8440
DOI:10.1016/j.heliyon.2023.e16964