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Nasal oxytocin administration does not influence eye gaze or perceived relationship of male volunteers with physicians in a simulated online consultation: a randomized, placebo-controlled trial.

التفاصيل البيبلوغرافية
العنوان: Nasal oxytocin administration does not influence eye gaze or perceived relationship of male volunteers with physicians in a simulated online consultation: a randomized, placebo-controlled trial.
المؤلفون: Jongerius C; Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands.; Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands., Hillen MA; Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands.; Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands., Smets EMA; Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands.; Amsterdam Public Health, Quality of Care, Amsterdam, The Netherlands., Mol MJ; Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands., Kooij ES; Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands., de Nood MA; Amsterdam UMC, Location AMC, Medical Psychology, Amsterdam, The Netherlands., Dalmaijer ES; MRC Cognition and Brain Sciences Unit, University of Cambridge, Cambridge, United Kingdom., Fliers E; Department of Endocrinology & Metabolism, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands., Romijn JA; Department of Medicine, Amsterdam Gastroenterology, Endocrinology & Metabolism, Amsterdam UMC, Location AMC, Amsterdam, The Netherlands., Quintana DS; University of Oslo, Department of Psychology, Oslo, Norway.; Department of Rare Disorders and Disabilities, Oslo University Hospital, NevSom, Oslo, Norway.; University of Oslo, Norwegian Centre for Mental Disorders Research (NORMENT) and KG Jebsen Centre for Neurodevelopmental Disorders, Oslo, Norway.
المصدر: Endocrine connections [Endocr Connect] 2023 Jul 31; Vol. 12 (8). Date of Electronic Publication: 2023 Jul 31.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioScientifica Country of Publication: England NLM ID: 101598413 Publication Model: Electronic Cited Medium: Print ISSN: 2049-3614 (Print) Linking ISSN: 20493614 NLM ISO Abbreviation: Endocr Connect Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Bristol : BioScientifica
مستخلص: The patient-physician relationship is a critical determinant of patient health outcomes. Verbal and non-verbal communication, such as eye gaze, are vital aspects of this bond. Neurobiological studies indicate that oxytocin may serve as a link between increased eye gaze and social bonding. Therefore, oxytocin signaling could serve as a key factor influencing eye gaze as well as the patient-physician relationship. We aimed to test the effects of oxytocin on gaze to the eyes of the physician and the patient-physician relationship by conducting a randomized placebo-controlled crossover trial in healthy volunteers with intranasally administered oxytocin (with a previously effective single dose of 24 IU, EudraCT number 2018-004081-34). The eye gaze of 68 male volunteers was studied using eye tracking during a simulated video call consultation with a physician, who provided information about vaccination against the human papillomavirus. Relationship outcomes, including trust, satisfaction, and perceived physician communication style, were measured using questionnaires and corrected for possible confounds (social anxiety and attachment orientation). Additional secondary outcome measures for the effect of oxytocin were recall of information and pupil diameter and exploratory outcomes included mood and anxiety measures. Oxytocin did not affect the eye-tracking parameters of volunteers' gaze toward the eyes of the physician. Moreover, oxytocin did not affect the parameters of bonding between volunteers and the physician nor other secondary and exploratory outcomes in this setting. Bayesian hypothesis testing provided evidence for the absence of effects. These results contradict the notion that oxytocin affects eye gaze patterns or bonding.
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فهرسة مساهمة: Keywords: crossover trial; eye gaze; eye-tracking; oxytocin; patient–physician relationship
تواريخ الأحداث: Date Created: 20230609 Latest Revision: 20230826
رمز التحديث: 20230826
مُعرف محوري في PubMed: PMC10448572
DOI: 10.1530/EC-22-0377
PMID: 37294605
قاعدة البيانات: MEDLINE
الوصف
تدمد:2049-3614
DOI:10.1530/EC-22-0377