دورية أكاديمية
Viral infectivity in paediatric SARS-CoV-2 clinical samples does not vary by age.
| العنوان: | Viral infectivity in paediatric SARS-CoV-2 clinical samples does not vary by age. |
|---|---|
| المؤلفون: | Schmidt MM; Department of Microbiology and Molecular Genetics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA., Despres HW; Department of Microbiology and Molecular Genetics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA., Shirley DJ; Data Science Department, Faraday, Inc., Burlington, VT, USA., Bose ME; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., McCaul KC; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Crothers JW; Department of Pathology and Laboratory Medicine, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA., Henrickson KJ; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA., Lee B; Department of Pediatrics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA., Bruce EA; Department of Microbiology and Molecular Genetics, Robert Larner, MD College of Medicine, University of Vermont, Burlington, VT, USA. |
| المصدر: | Access microbiology [Access Microbiol] 2023 May 26; Vol. 5 (5). Date of Electronic Publication: 2023 May 26 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Microbiology Society Country of Publication: England NLM ID: 101746927 Publication Model: eCollection Cited Medium: Internet ISSN: 2516-8290 (Electronic) Linking ISSN: 25168290 NLM ISO Abbreviation: Access Microbiol Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Microbiology Society, [2019]- |
| مستخلص: | At the start of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, there was much uncertainty about the role of children in infection and transmission dynamics. Through the course of the pandemic, it became clear that children were susceptible to SARS-CoV-2 infection, although they were experiencing a notable lack of severe disease outcomes as compared to the adult population. This trend held true with the emergence of new SARS-CoV-2 variants, even in paediatric populations that were ineligible to be vaccinated. The difference in disease outcomes has prompted questions about the virological features of SARS-CoV-2 infection in this population. In order to determine if there was any difference in the infectivity of the virus produced by children with coronavirus disease 2019 (COVID-19), we compared viral RNA levels (clinical RT-qPCR C Competing Interests: The authors declare that there are no conflicts of interest. (© 2023 The Authors.) |
| التعليقات: | Update of: medRxiv. 2022 Oct 18;:. (PMID: 36299435) |
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| معلومات مُعتمدة: | P30 GM118228 United States GM NIGMS NIH HHS |
| فهرسة مساهمة: | Keywords: SARS-CoV-2; clinical isolates; paediatric; viral infectivity |
| تواريخ الأحداث: | Date Created: 20230616 Latest Revision: 20240603 |
| رمز التحديث: | 20240603 |
| مُعرف محوري في PubMed: | PMC10267661 |
| DOI: | 10.1099/acmi.0.000547.v4 |
| PMID: | 37323941 |
| قاعدة البيانات: | MEDLINE |
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