دورية أكاديمية
أعرض في EDS

The First Brazilian Cardiovascular Registry of Atrial Fibrillation: Primary Results of the RECALL Study.

التفاصيل البيبلوغرافية
العنوان: The First Brazilian Cardiovascular Registry of Atrial Fibrillation: Primary Results of the RECALL Study.
المؤلفون: Lopes RD; Brazilian Clinical Research Institute, Sao Paulo, SP, Brazil; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC. Electronic address: renato.lopes@dm.duke.edu., de Barros E Silva PGM; Brazilian Clinical Research Institute, Sao Paulo, SP, Brazil; HCOR Research Institute, São Paulo, SP, Brazil; Hospital Samaritano Paulista, São Paulo, SP, Brazil., Filho CRH; Hospital Regional Hans Dieter Schmidt, Joinville, SC, Brazil., Cavalvante MA; Hospital Regional de Presidente Prudente, Presidente Prudente, SP, Brazil., Miranda CM; Hospital Madre Teresa Belo Horizonte, MG, Brazil., Esper RB; Instituto Prevent Senior, Sao Paulo, SP, Brazil., de Lima GG; Instituto de Cardiologia do Rio Grande do Sul, Porto Alegre, RS, Brazil., Ritt LEF; D'or Research Institute, Hospital Cardio Pulmomar, Salvador, BA, Brazil; Bahiana School of Medicine and Public Health, Salvador, BA, Brazil., da Silva RMFL; Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil., Nakazone MA; Faculdade de Medicina de Sao José do Rio Preto, Sao José do Rio Preto, SP, Brazil., Almeida AP; Unidade Médico Cirúrgica - UNIMEC, Vitória da Conquista, BA, Brazil., Pavanello R; HCOR Research Institute, São Paulo, SP, Brazil., de Lima CEB; Hospital Universitário da Universidade Federal do Piauí, Teresina, PI, Brazil., Backes LM; Hospital São Vicente de Paulo, Passo Fundo, RS, Brazil., Oliveira LH; Hospital Ana Nery, Salvador, BA, Brazil., de Souza OF; Hospital Copa D'Or, Rio de Janeiro, RJ, Brazil., Filho AML; Instituto de Moléstias Cardiovasculares, São José do Rio Preto, SP, Brazil., God EMG; Hospital Socor, Belo Horizonte, MG, Brazil., Jorge JCM; Clínica da Irmandade da Santa Casa de Curitiba, Curitiba, PR, Brazil., de Almeida Luiz A; Universidade Estadual do Oeste do Paraná, Cascavel, PR, Brazil; Hospital Universitário do Oeste do Paraná, Cascavel, PR, Brazil., Martins SFPP; Centro Municipal de Especialidades da Prefeitura Municipal de Vitória, Vitória, ES, Brazil., Dantas RC; Hospital Santo Antônio Curvelo (Irmandade de Santo Antonio de Curvelo), Curvelo, MG, Brazil., D Oliveira Vieira R; Hospital e Clínica São Roque, Ipiaú, BA, Brazil., Zimerman LI; Hospital de Clínicas de Porto Alegre, Porto Alegre, RS, Brazil., Júnior ÁRA; Fundação Bahiana de Cardiologia, Salvador, BA, Brazil., de Oliveira Figueiredo MJ; Hospital de Clínicas da Universidade Estadual de Campinas, Campinas, SP, Brazil., do Carmo Gomes SP; HCOR Research Institute, São Paulo, SP, Brazil., de Lima LM; HCOR Research Institute, São Paulo, SP, Brazil., Damiani LP; Brazilian Clinical Research Institute, Sao Paulo, SP, Brazil; HCOR Research Institute, São Paulo, SP, Brazil., Teixeira RA; Sociedade Brasileira de Arritmias Cardíacas, Sao Paulo, SP, Brazil; Hospital Renascentista, Pouso Alegre, MG, Brazil; Universidade do Vale do Sapucaí, Pouso Alegre, MG, Brazil., Fagundes AA; Sociedade Brasileira de Arritmias Cardíacas, Sao Paulo, SP, Brazil., Saad EB; Sociedade Brasileira de Arritmias Cardíacas, Sao Paulo, SP, Brazil; Hospital Pró-Cardíaco, Rio de Janeiro, RJ, Brazil; Hospital Samaritano Botafogo, Rio de Janeiro, RJ, Brazil.
مؤلفون مشاركون: RECALL Investigators
المصدر: American heart journal [Am Heart J] 2023 Oct; Vol. 264, pp. 97-105. Date of Electronic Publication: 2023 Jun 15.
نوع المنشور: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 0370465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6744 (Electronic) Linking ISSN: 00028703 NLM ISO Abbreviation: Am Heart J Subsets: MEDLINE
أسماء مطبوعة: Original Publication: St. Louis, MO : Mosby
مواضيع طبية MeSH: Atrial Fibrillation*/epidemiology , Atrial Fibrillation*/therapy , Atrial Fibrillation*/complications , Stroke*/epidemiology , Stroke*/etiology , Stroke*/prevention & control, Humans ; Female ; Aged ; Male ; Brazil/epidemiology ; Risk Factors ; Anticoagulants ; Hemorrhage/chemically induced ; Registries
مستخلص: Background: It is estimated that atrial fibrillation (AF) affects approximately 1.5 million people in Brazil; however, epidemiological data are limited. We sought to evaluate the characteristics, treatment patterns, and clinical outcomes in patients with AF in Brazil by creating the first nationwide prospective registry.
Methods: RECALL was a multicenter, prospective registry that included and followed for 1 year 4,585 patients with AF at 89 sites across Brazil from April 2012 to August 2019. Patient characteristics, concomitant medication use, and clinical outcomes were analyzed using descriptive statistics and multivariable models.
Results: Of 4,585 patients enrolled, the median age was 70 (61, 78) years, 46% were women, and 53.8% had permanent AF. Only 4.4% of patients had a history of previous AF ablation and 25.2% had a previous cardioversion. The mean (SD) CHA 2 DS 2 -VASc score was 3.2 (1.6); median HAS-BLED score was 2 (2, 3). At baseline, 22% were not on anticoagulants. Of those taking anticoagulants, 62.6% were taking vitamin K antagonists and 37.4% were taking direct oral anticoagulants. The primary reasons for not using an oral anticoagulant were physician judgment (24.6%) and difficulty in controlling (14.7%) or performing (9.9%) INR. Mean (SD) TTR for the study period was 49.5% (27.5). During follow-up, the use of anticoagulants and INR in the therapeutic range increased to 87.1% and 59.1%, respectively. The rates/100 patient-years of death, hospitalization due to AF, AF ablation, cardioversion, stroke, systemic embolism, and major bleeding were 5.76 (5.12-6.47), 15.8 (14.6-17.0), 5.0 (4.4-5.7), 1.8 (1.4-2.2), 2.77 (2.32-3.32), 1.01 (0.75-1.36), and 2.21 (1.81-2.70). Older age, permanent AF, New York Heart Association class III/IV, chronic kidney disease, peripheral arterial disease, stroke, chronic obstructive pulmonary disease, and dementia were independently associated with increased mortality while the use of anticoagulant was associated with lower risk of death.
Conclusions: RECALL represents the largest prospective registry of patients with AF in Latin America. Our findings highlight important gaps in treatment, which can inform clinical practice and guide future interventions to improve the care of these patients.
(Copyright © 2023. Published by Elsevier Inc.)
المشرفين على المادة: 0 (Anticoagulants)
تواريخ الأحداث: Date Created: 20230617 Date Completed: 20230918 Latest Revision: 20231010
رمز التحديث: 20231215
DOI: 10.1016/j.ahj.2023.06.007
PMID: 37330162
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-6744
DOI:10.1016/j.ahj.2023.06.007