دورية أكاديمية
Impact of corticosteroid administration on the response of exposed dental pulp to capping with bioactive cements-experimental study on mongrel dogs.
| العنوان: | Impact of corticosteroid administration on the response of exposed dental pulp to capping with bioactive cements-experimental study on mongrel dogs. |
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| المؤلفون: | Soliman HA; Conservative Dentistry Department, Faculty of Dentistry, Kafrelsheikh University, Kafrelsheikh, Egypt., El-Toukhy RI; Conservative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt., Ibrahim MMA; Oral Pathology Department, Faculty of Dentistry, Mansoura University, Dakahlia Governorate, Egypt. monamohsen@mans.edu.eg.; Oral Pathology Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt. monamohsen@mans.edu.eg., Grawish ME; Oral Biology Department, Faculty of Dentistry, Mansoura University, Dakahlia Governorate, Egypt.; Oral Biology Department, Faculty of Oral and Dental Medicine, Delta University for Science and Technology, Dakahlia Governorate, Egypt., Kader Sobh MA; Nephrology Department, Urology and Nephrology Center, Faculty of Medicine, Mansoura, Egypt., Mahmoud SH; Conservative Dentistry Department, Faculty of Dentistry, Horus University, New Damietta City, Egypt.; Conservative Dentistry Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt. |
| المصدر: | BMC oral health [BMC Oral Health] 2023 Jun 26; Vol. 23 (1), pp. 423. Date of Electronic Publication: 2023 Jun 26. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: BioMed Central Country of Publication: England NLM ID: 101088684 Publication Model: Electronic Cited Medium: Internet ISSN: 1472-6831 (Electronic) Linking ISSN: 14726831 NLM ISO Abbreviation: BMC Oral Health Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : BioMed Central, [2001- |
| مواضيع طبية MeSH: | Pulpitis*/drug therapy , Pulp Capping and Pulpectomy Agents*/pharmacology , Pulp Capping and Pulpectomy Agents*/therapeutic use, Animals ; Dogs ; Male ; Dental Pulp ; Dental Pulp Capping/methods ; Calcium Compounds/pharmacology ; Calcium Compounds/therapeutic use ; Silicates/pharmacology ; Silicates/therapeutic use ; Adrenal Cortex Hormones/pharmacology ; Oxides/pharmacology ; Oxides/therapeutic use ; Drug Combinations ; Aluminum Compounds/pharmacology ; Aluminum Compounds/therapeutic use |
| مستخلص: | Background: Corticosteroids are commonly used as a treatment for a variety of pathological conditions, however, systemic corticosteroid administration has adverse effects including impaired immune response and wound healing. Such complications may affect pulp healing after direct pulp capping. The current study evaluated the influence of corticosteroids on the healing ability of exposed dogs' dental pulps after direct pulp capping (DPC) with bioactive materials. Methods: Ten healthy male dogs were assigned randomly into two groups, 5 dogs each: group I represent the control group which did not receive any medication, and group II was given corticosteroid for 45 days before DPC and till the dogs were euthanized (n = 75 teeth for each group). Following mechanical exposure, the pulps were randomly capped with either Ca(OH) Results: The corticosteroid-treated group revealed no significant difference compared to the control group concerning the pulp healing response (P > 0.05). Both Biodentine and MTA-treated specimens revealed significant differences with Ca(OH) Conclusions: Direct pulp capping technique whenever indicated in subjects treated with corticosteroid immunosuppressive drugs like prednisone performed well in aseptic conditions especially when capped with bioactive materials. (© 2023. The Author(s).) |
| References: | Int J Mol Cell Med. 2014 Fall;3(4):263-71. (PMID: 25635253) J Vet Dent. 2001 Sep;18(3):122-5. (PMID: 11968904) Int Endod J. 2015 Dec;48(12):1122-8. (PMID: 25393585) J Endod. 2010 Jan;36(1):95-9. (PMID: 20003943) Materials (Basel). 2020 Sep 04;13(18):. (PMID: 32899877) Biomed Res Int. 2014;2014:745139. (PMID: 24804241) J Endod. 2006 Nov;32(11):1066-73. (PMID: 17055908) Dent Traumatol. 2001 Aug;17(4):163-6. (PMID: 11585142) J Dent. 2014 Sep;42(9):1156-70. (PMID: 25008021) Pharmacol Res. 2008 Aug;58(2):137-47. (PMID: 18602009) Int J Mol Med. 2021 Jul;48(1):. (PMID: 34013376) Eur J Dent. 2016 Jul-Sep;10(3):370-375. (PMID: 27403056) Cell Tissue Res. 2005 Sep;321(3):391-400. (PMID: 15988617) Dent Traumatol. 2012 Feb;28(1):25-32. (PMID: 21895969) Mediators Inflamm. 2015;2015:230251. (PMID: 26538821) Oper Dent. 2009 Sep-Oct;34(5):615-25. (PMID: 19830978) Int Endod J. 2012 May;45(5):439-48. (PMID: 22188368) Int Endod J. 2003 Mar;36(3):225-31. (PMID: 12657149) Clin Oral Investig. 2022 Feb;26(2):1417-1425. (PMID: 34370099) J Endod. 2014 Dec;40(12):1932-9. (PMID: 25312886) Wound Repair Regen. 2009 Sep-Oct;17(5):758-61. (PMID: 19769728) J Endod. 2012 Aug;38(8):1126-9. (PMID: 22794220) Clin Oral Investig. 2018 Jun;22(5):2021-2029. (PMID: 29234957) J Clin Diagn Res. 2017 Aug;11(8):ZG01-ZG05. (PMID: 28969295) J Endod. 2018 Oct;44(10):1534-1541. (PMID: 30174104) CBE Life Sci Educ. 2013 Fall;12(3):345-51. (PMID: 24006382) Clin Oral Investig. 2014;18(5):1383-9. (PMID: 24043482) Eur Endod J. 2021 Mar;6(1):128-129. (PMID: 33776024) Int Endod J. 2017 Oct;50(10):924-932. (PMID: 27891629) J Biomed Mater Res B Appl Biomater. 2018 Apr;106(3):1358-1368. (PMID: 28561919) J Med Signals Sens. 2011 Jan;1(1):55-61. (PMID: 22606659) Rheum Dis Clin North Am. 2016 Feb;42(1):15-31, vii. (PMID: 26611548) ALTEX. 2010;27(4):285-303. (PMID: 21240470) J Dent Res. 2012 May;91(5):454-9. (PMID: 22436906) |
| فهرسة مساهمة: | Keywords: Corticosteroid; Direct pulp capping technique; Dogs’ teeth; Pulp capping material |
| المشرفين على المادة: | 404G39282C (tricalcium silicate) 0 (Calcium Compounds) 0 (Silicates) 0 (Adrenal Cortex Hormones) 0 (Oxides) 0 (Pulp Capping and Pulpectomy Agents) 0 (Drug Combinations) 0 (Aluminum Compounds) |
| تواريخ الأحداث: | Date Created: 20230626 Date Completed: 20230628 Latest Revision: 20230701 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC10294540 |
| DOI: | 10.1186/s12903-023-03119-3 |
| PMID: | 37365555 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1472-6831 |
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| DOI: | 10.1186/s12903-023-03119-3 |