دورية أكاديمية

Ewing's sarcoma of the head and neck: A systematic review.

التفاصيل البيبلوغرافية
العنوان: Ewing's sarcoma of the head and neck: A systematic review.
المؤلفون: Spiguel MH; Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Schuch LF; Department of Oral Diagnosis, Piracicaba School of Dentistry, Universidade Estadual de Campinas, Piracicaba, Brazil., Kovalski LN; Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Ribeiro JT; Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Só BB; Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil., Silveira FM; Molecular Pathology Area, School of Dentistry, Universidad de la República (UDELAR), Montevideo, Uruguay., Vargas PA; Department of Oral Diagnosis, Piracicaba School of Dentistry, Universidade Estadual de Campinas, Piracicaba, Brazil., Martins MAT; Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Department of Oral Medicine, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil., Zanella VG; Head and Neck Surgery Department, Hospital Santa Rita, Complexo Hospitalar Santa Casa, Porto Alegre, Brazil., Aleixo PB; Pathology Department, Hospital Santa Rita, Complexo Hospitalar Santa Casa, Porto Alegre, Brazil., Wagner VP; Academic Unit of Oral and Maxillofacial Medicine and Pathology, Department of Clinical Dentistry, University of Sheffield, Sheffield, UK., Martins MD; Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.; Department of Oral Diagnosis, Piracicaba School of Dentistry, Universidade Estadual de Campinas, Piracicaba, Brazil.
المصدر: Oral diseases [Oral Dis] 2024 May; Vol. 30 (4), pp. 1784-1792. Date of Electronic Publication: 2023 Jul 01.
نوع المنشور: Systematic Review; Journal Article; Review; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Munksgaard Country of Publication: Denmark NLM ID: 9508565 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1601-0825 (Electronic) Linking ISSN: 1354523X NLM ISO Abbreviation: Oral Dis Subsets: MEDLINE
أسماء مطبوعة: Publication: 2001- : Copenhagen, Denmark : Munksgaard
Original Publication: Houndmills, Basingstoke, Hampshire, UK : Stockton Press, c1995-
مواضيع طبية MeSH: Head and Neck Neoplasms*/pathology , Head and Neck Neoplasms*/therapy , Sarcoma, Ewing*/therapy , Sarcoma, Ewing*/pathology, Female ; Humans ; Male ; Neoplasm Recurrence, Local ; Survival Rate ; Young Adult
مستخلص: Objective: The aim of the present study was to conduct a systematic review of head and neck Ewing sarcoma (ES) concerning patients' demographic and clinical features, histopathological findings, treatment, follow-up, and survival rate.
Materials and Methods: An electronic search was undertaken in four databases. Articles describing case reports or case series were included. Outcomes were evaluated by the Kaplan-Meier method along with Cox regression.
Results: The search yielded 186 studies describing 227 ES cases. The mean age was 22.7 years, and males were slightly more affected. Interestingly, more than half the cases were diagnosed up to 20 years. The respiratory tract was the most reported site, followed by the jawbones. Clinically, symptomatic swelling or nodules were described, with a mean duration of 4 months. Management involved multimodal treatment regimens. Local recurrence, lymph node and distant metastasis were observed in 10.7%, 12.6%, and 20.3% of cases, respectively. Statistical analysis revealed that older patients with distant metastasis had a lower overall survival rate (p < 0.05).
Conclusion: This study provides an overall view of head and neck ES that can assist oral and maxillofacial pathologists with the diagnosis and extend the knowledge of surgeons and oncologists about this condition.
(© 2023 Wiley Periodicals LLC.)
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فهرسة مساهمة: Keywords: Ewing sarcoma; head and neck cancer; head and neck neoplasms; pediatrics; sarcoma
تواريخ الأحداث: Date Created: 20230701 Date Completed: 20240531 Latest Revision: 20240702
رمز التحديث: 20240703
DOI: 10.1111/odi.14644
PMID: 37392420
قاعدة البيانات: MEDLINE
الوصف
تدمد:1601-0825
DOI:10.1111/odi.14644