دورية أكاديمية
Telling Your Right Hand from Your Left: The Effects of DNA Supercoil Handedness on the Actions of Type II Topoisomerases.
| العنوان: | Telling Your Right Hand from Your Left: The Effects of DNA Supercoil Handedness on the Actions of Type II Topoisomerases. |
|---|---|
| المؤلفون: | Jian JY; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA., Osheroff N; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.; Department of Medicine (Hematology/Oncology), Vanderbilt University School of Medicine, Nashville, TN 37232, USA. |
| المصدر: | International journal of molecular sciences [Int J Mol Sci] 2023 Jul 07; Vol. 24 (13). Date of Electronic Publication: 2023 Jul 07. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel, Switzerland : MDPI, [2000- |
| مواضيع طبية MeSH: | DNA Topoisomerases, Type II*/metabolism , Functional Laterality*, Humans ; DNA ; Isomerases/genetics ; DNA Replication ; DNA Topoisomerases, Type I/metabolism |
| مستخلص: | Type II topoisomerases are essential enzymes that modulate the topological state of DNA supercoiling in all living organisms. These enzymes alter DNA topology by performing double-stranded passage reactions on over- or underwound DNA substrates. This strand passage reaction generates a transient covalent enzyme-cleaved DNA structure known as the cleavage complex. Al-though the cleavage complex is a requisite catalytic intermediate, it is also intrinsically dangerous to genomic stability in biological systems. The potential threat of type II topoisomerase function can also vary based on the nature of the supercoiled DNA substrate. During essential processes such as DNA replication and transcription, cleavage complex formation can be inherently more dangerous on overwound versus underwound DNA substrates. As such, it is important to understand the profound effects that DNA topology can have on the cellular functions of type II topoisomerases. This review will provide a broad assessment of how human and bacterial type II topoisomerases recognize and act on their substrates of various topological states. |
| References: | Int J Mol Sci. 2018 Sep 14;19(9):. (PMID: 30223465) Cell Chem Biol. 2019 Apr 18;26(4):502-511.e3. (PMID: 30713098) J Biol Chem. 1996 Dec 6;271(49):31549-55. (PMID: 8940171) J Mol Biol. 2012 Dec 7;424(3-4):109-24. (PMID: 22841979) Biochemistry. 2021 Jun 1;60(21):1630-1641. (PMID: 34008964) Chem Biol. 2010 May 28;17(5):421-33. (PMID: 20534341) Biochemistry. 2017 Oct 10;56(40):5440-5448. (PMID: 28921956) J Mol Biol. 2013 Sep 9;425(17):3029-45. (PMID: 23867279) Biochemistry. 1989 Oct 3;28(20):8154-60. (PMID: 2557897) J Biol Chem. 2005 Nov 25;280(47):39337-45. (PMID: 16188892) Biochemistry. 2006 Sep 26;45(38):11674-80. (PMID: 16981727) Cell. 1990 Oct 19;63(2):393-404. (PMID: 2170028) Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8654-9. (PMID: 12857958) Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4057-62. (PMID: 8633016) J Biol Chem. 1995 Oct 20;270(42):25286-90. (PMID: 7559669) Nat Rev Mol Cell Biol. 2011 Nov 23;12(12):827-41. (PMID: 22108601) Nat Commun. 2013;4:1598. (PMID: 23511463) EMBO Rep. 2007 Feb;8(2):147-51. (PMID: 17268506) Nucleic Acids Res. 2009 Feb;37(3):702-11. (PMID: 19188255) J Cell Biol. 1986 Dec;103(6 Pt 2):2569-81. (PMID: 3025219) Metallomics. 2010 Jul;2(7):450-9. (PMID: 20703329) Proc Natl Acad Sci U S A. 1989 Dec;86(23):9431-5. (PMID: 2556712) Genes Dev. 1995 Nov 15;9(22):2859-69. (PMID: 7590259) Science. 2000 Jan 7;287(5450):131-4. (PMID: 10615047) Biochemistry. 2011 Apr 19;50(15):3240-9. (PMID: 21413765) Proc Natl Acad Sci U S A. 1988 Feb;85(4):1086-90. (PMID: 2829215) Cancer Res. 1997 Oct 1;57(19):4301-8. (PMID: 9331091) Biochemistry. 2006 Mar 7;45(9):3040-50. (PMID: 16503659) Cell Mol Life Sci. 2010 Jun;67(12):2001-24. (PMID: 20165898) Mol Microbiol. 2004 May;52(4):925-31. (PMID: 15130115) Cell Cycle. 2007 Jul 15;6(14):1705-12. (PMID: 17622799) Biochem Mol Biol Educ. 2008;37(1):2-10. (PMID: 19225573) Annu Rev Biochem. 2013;82:139-70. (PMID: 23495937) Sci Am. 1980 Jul;243(1):100-13. (PMID: 6256851) Nat Struct Mol Biol. 2012 Nov;19(11):1147-54. (PMID: 23022727) J Biol Chem. 1998 Dec 11;273(50):33660-6. (PMID: 9837951) Nucleic Acids Res. 2012 Nov;40(21):10893-903. (PMID: 22977179) Nat Rev Cancer. 2009 May;9(5):327-37. (PMID: 19377505) Exp Cell Res. 1999 Sep 15;251(2):329-39. (PMID: 10471318) Nature. 2010 Jun 3;465(7298):641-4. (PMID: 20485342) J Biol Chem. 1987 Jul 25;262(21):10362-8. (PMID: 3038875) Cell. 1988 Jul 29;54(3):403-11. (PMID: 2840207) Nucleic Acids Res. 2009 Feb;37(3):738-48. (PMID: 19042970) Nucleic Acids Res. 2012 Dec;40(22):11428-34. (PMID: 23066100) Biochim Biophys Acta. 1998 Oct 1;1400(1-3):29-43. (PMID: 9748489) J Biol Chem. 1994 Jan 14;269(2):1173-6. (PMID: 8288578) Cell. 1985 Jun;41(2):553-63. (PMID: 2985283) Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14416-21. (PMID: 8962066) EMBO Rep. 2004 Mar;5(3):256-61. (PMID: 14993926) Genes Dev. 2000 Nov 15;14(22):2881-92. (PMID: 11090135) Nat Rev Cancer. 2009 May;9(5):338-50. (PMID: 19377506) Elife. 2021 Jun 28;10:. (PMID: 34180392) J Biol Chem. 2000 Apr 28;275(17):13041-8. (PMID: 10777608) Mol Gen Genet. 1984;196(3):508-12. (PMID: 6094979) Mol Cell. 2008 Jun 20;30(6):790-802. (PMID: 18570880) Annu Rev Biophys Biomol Struct. 2004;33:95-118. (PMID: 15139806) Biochemistry. 2014 Mar 18;53(10):1565-74. (PMID: 24576155) Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2925-30. (PMID: 22323612) J Biol Chem. 1983 Aug 10;258(15):9536-43. (PMID: 6308011) Nucleic Acids Res. 1998 Sep 15;26(18):4205-13. (PMID: 9722641) Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6986-91. (PMID: 19359479) Nucleic Acids Res. 2006 Jun 06;34(10):3128-38. (PMID: 16757578) J Biol Chem. 1986 Jul 25;261(21):9944-50. (PMID: 3015913) Nucleic Acids Res. 2011 Jun;39(11):4808-17. (PMID: 21300644) Nucleic Acids Res. 2008 Sep;36(15):4883-93. (PMID: 18653531) Proc Natl Acad Sci U S A. 1984 Jun;81(11):3322-6. (PMID: 6587352) Science. 2011 Mar 11;331(6022):1328-32. (PMID: 21393545) Biochemistry. 2009 Sep 29;48(38):8940-7. (PMID: 19697956) Nature. 1987 Mar 26-Apr 1;326(6111):414-6. (PMID: 2436053) Cell. 1980 Aug;21(1):115-25. (PMID: 6250707) Nucleic Acids Res. 2023 May 8;51(8):3888-3902. (PMID: 36999602) J Biol Chem. 2013 May 10;288(19):13695-703. (PMID: 23508957) EMBO J. 1990 Dec;9(13):4555-62. (PMID: 2176156) Int J Mol Sci. 2019 Mar 12;20(5):. (PMID: 30871006) Proc Natl Acad Sci U S A. 1976 Nov;73(11):3872-6. (PMID: 186775) Cell Rep. 2019 Oct 8;29(2):422-436.e5. (PMID: 31597101) Cell. 1998 Sep 18;94(6):819-27. (PMID: 9753328) Nucleic Acids Res. 2009 Feb;37(3):661-71. (PMID: 19240147) Genes (Basel). 2019 Oct 30;10(11):. (PMID: 31671531) ACS Infect Dis. 2019 Apr 12;5(4):570-581. (PMID: 30757898) Biochemistry. 2014 Oct 21;53(41):6595-602. (PMID: 25280269) J Bacteriol. 2006 Apr;188(8):3002-11. (PMID: 16585761) Nucleic Acids Res. 2009 Feb;37(3):679-92. (PMID: 19208647) Bioessays. 2021 Apr;43(4):e2000286. (PMID: 33480441) Nature. 1998 Jun 11;393(6685):537-44. (PMID: 9634230) J Biol Chem. 1992 Dec 25;267(36):25676-84. (PMID: 1334483) Genome Res. 2017 Jul;27(7):1238-1249. (PMID: 28385713) Nature. 2007 Dec 20;450(7173):1201-5. (PMID: 18097402) Biochemistry. 2017 Aug 15;56(32):4191-4200. (PMID: 28708938) Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22055-9. (PMID: 21076033) Cell Growth Differ. 1991 Apr;2(4):209-14. (PMID: 1651102) Nucleic Acids Res. 2017 Sep 19;45(16):9611-9624. (PMID: 28934496) Biophys Rev. 2016 Nov;8(Suppl 1):1-3. (PMID: 28510213) Nat Commun. 2021 May 20;12(1):2962. (PMID: 34016969) Proc Natl Acad Sci U S A. 2004 May 11;101(19):7293-8. (PMID: 15123801) J Mol Biol. 1983 Nov 15;170(4):983-1007. (PMID: 6644817) Proc Natl Acad Sci U S A. 1988 Oct;85(19):7177-81. (PMID: 2845399) Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9419-24. (PMID: 10944214) J Mol Biol. 1989 Jul 20;208(2):257-67. (PMID: 2549254) EMBO J. 2003 Jan 2;22(1):151-63. (PMID: 12505993) Nucleic Acids Res. 1980 Sep 11;8(17):3865-74. (PMID: 6255421) Biochemistry. 2008 Dec 16;47(50):13169-78. (PMID: 19053267) Cell Rep. 2015 Dec 22;13(11):2587-2596. (PMID: 26686641) J Cell Biol. 2002 Apr 1;157(1):31-44. (PMID: 11927602) J Mol Biol. 2005 Aug 19;351(3):545-61. (PMID: 16023670) J Biol Chem. 1980 Mar 10;255(5):2211-9. (PMID: 6243661) J Biol Chem. 1993 Apr 15;268(11):8096-104. (PMID: 8385137) Biochemistry. 2022 Oct 4;61(19):2148-2158. (PMID: 36122251) Ann N Y Acad Sci. 2014 Mar;1310:98-110. (PMID: 24495080) J Mol Biol. 2001 Jan 19;305(3):441-50. (PMID: 11152602) J Biol Chem. 2006 Feb 10;281(6):3738-42. (PMID: 16332690) Nature. 1953 Apr 25;171(4356):737-8. (PMID: 13054692) Proc Natl Acad Sci U S A. 1987 Oct;84(20):7024-7. (PMID: 2823250) Biochimie. 2007 Apr;89(4):427-46. (PMID: 17293019) Science. 2006 Jun 23;312(5781):1798-802. (PMID: 16794079) Cell. 1987 Sep 11;50(6):917-25. (PMID: 3040264) Curr Opin Struct Biol. 2013 Feb;23(1):125-33. (PMID: 23265999) Nucleic Acids Res. 2013 May 1;41(10):5444-56. (PMID: 23580548) Mol Cell. 2016 Oct 6;64(1):134-147. (PMID: 27716481) Nat Rev Mol Cell Biol. 2016 Nov;17(11):703-721. (PMID: 27649880) Exp Cell Res. 1997 Dec 15;237(2):452-5. (PMID: 9434641) Nucleic Acids Res. 2007;35(11):3810-22. (PMID: 17526531) J Biol Chem. 1993 Jul 5;268(19):14250-5. (PMID: 8390987) Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8219-26. (PMID: 11459956) |
| معلومات مُعتمدة: | I01 BX002198 United States BX BLRD VA; R01 AI170546 United States AI NIAID NIH HHS; R01 GM126363 United States GM NIGMS NIH HHS |
| فهرسة مساهمة: | Keywords: DNA cleavage; DNA relaxation; DNA topoisomerase; DNA topology; supercoil handedness; type II topoisomerase |
| المشرفين على المادة: | EC 5.99.1.3 (DNA Topoisomerases, Type II) 9007-49-2 (DNA) EC 5.- (Isomerases) EC 5.99.1.2 (DNA Topoisomerases, Type I) |
| تواريخ الأحداث: | Date Created: 20230714 Date Completed: 20230717 Latest Revision: 20240117 |
| رمز التحديث: | 20240117 |
| مُعرف محوري في PubMed: | PMC10342825 |
| DOI: | 10.3390/ijms241311199 |
| PMID: | 37446377 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder كن أول من يترك تعليقا!