دورية أكاديمية
Novel compounds of Djulis ( Chenopodium formosanum Koidz ) increases collagen, antioxidants, inhibits adipogenesis.
العنوان: | Novel compounds of Djulis ( Chenopodium formosanum Koidz ) increases collagen, antioxidants, inhibits adipogenesis. |
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المؤلفون: | Lin YY; Research & Design Center, TCI CO., Ltd, Taipei, Taiwan., Lin YK; Institute of Food Safety and Risk Management, National Taiwan Ocean University, Keelung, Taiwan.; Department of Food Science, National Taiwan Ocean University, Keelung, Taiwan.; Graduate Institute of Biomedical Engineering, National Chung Hsing University, Taichung, Taiwan., Lin YH; Research & Design Center, TCI CO., Ltd, Taipei, Taiwan., Chiang CF; Research & Design Center, TCI CO., Ltd, Taipei, Taiwan. |
المصدر: | Natural product research [Nat Prod Res] 2024 Aug; Vol. 38 (16), pp. 2763-2772. Date of Electronic Publication: 2023 Jul 15. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Taylor & Francis Health Sciences Country of Publication: England NLM ID: 101167924 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-6427 (Electronic) Linking ISSN: 14786419 NLM ISO Abbreviation: Nat Prod Res Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Milton Park, UK : Taylor & Francis Health Sciences, c2003- |
مواضيع طبية MeSH: | Antioxidants*/chemistry , Antioxidants*/pharmacology , Flavonoids*/chemistry , Flavonoids*/pharmacology , Flavonoids*/isolation & purification , Collagen*/chemistry , Chenopodium*/chemistry , Phenols*/chemistry , Phenols*/pharmacology , Phenols*/isolation & purification, Alkaloids/chemistry ; Alkaloids/pharmacology ; Alkaloids/isolation & purification ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Molecular Structure ; Animals ; Polyphenols/chemistry ; Polyphenols/pharmacology ; Sterols/chemistry ; Sterols/pharmacology ; Sterols/isolation & purification |
مستخلص: | Djulis ( Chenopodium formosanum Koidz ), is rich in nutrients and contains various bioactive components such as polyphenols and alkaloids. The new compound has a broad application prospect, including food additives, health products, drugs, etc. The purpose of this study was to find out new compounds from Djulis. It was found that 24 compounds including 7 phenols, 11 flavonoids, 4 plant alkaloids, 2 sterols. Among those, TCI-CF-22-S (Methyl 3,6-dihydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate), TCI-CF-23-S (Methyl 6-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate), TCI-CF-24-S (Kaempferol-3-O-b-D-apifuranosyl-(1→2)-a-L-arabinopyranoside) were isolated from djulis sources for the first time, and the structures of compounds were assigned by 1D, 2D NMR spectroscopy. TCI-CF-01(Caffeic acid), TCI-CF-02 (20-Hydroxyecdysone), TCI-CF-03 (Japonicone), TCI-CF-04 (3,4-Dihydroxyphenylacetiate), TCI-CF-05 (Quercetin-3-O-rutinoside-7-O-rhamnopyranoside), TCI-CF-06 (Guanosine), TCI-CF-07(Adenine), TCI-CF-08 (Coumaric acid) increased collagen production, and TCI-CF-03 (Japonicone), TCI-CF-04 (3,4-Dihydroxyphenylacetiate), TCI-CF-06 (Guanosine), TCI-CF-17 (Rutin), TCI-CF-20 (Protocatechuic acid) decreased advanced glycation end products (AGEs). In addition, TCI-CF-22-S (Methyl 6-hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate), TCI-CF-23-S (Methyl 3,6-dihydroxy-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylate) inhibited the formation of fatty oil droplets. Djulis has 24 compounds that may have various applications, including increasing collagen production and reducing advanced glycation end products and fatty oil droplets. |
فهرسة مساهمة: | Keywords: Antioxidants; chenolactam; chenopodium formosanum; collagen; djulis |
المشرفين على المادة: | 0 (Antioxidants) 0 (Flavonoids) 9007-34-5 (Collagen) 0 (Phenols) 0 (Alkaloids) 0 (Plant Extracts) 0 (Polyphenols) 0 (Sterols) |
تواريخ الأحداث: | Date Created: 20230715 Date Completed: 20240727 Latest Revision: 20240813 |
رمز التحديث: | 20240814 |
DOI: | 10.1080/14786419.2023.2235064 |
PMID: | 37452702 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1478-6427 |
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DOI: | 10.1080/14786419.2023.2235064 |