دورية أكاديمية
Confounding adjustment in observational studies on cardiothoracic interventions: a systematic review of methodological practice.
| العنوان: | Confounding adjustment in observational studies on cardiothoracic interventions: a systematic review of methodological practice. |
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| المؤلفون: | Velders BJJ; Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands., Boltje JWT; Department of Cardiothoracic Surgery, Amsterdam University Medical Center, Amsterdam, Netherlands., Vriesendorp MD; Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands., Klautz RJM; Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, Netherlands., Le Cessie S; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.; Department of Biomedical Data Science, Leiden University Medical Center, Leiden, Netherlands., Groenwold RHH; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.; Department of Biomedical Data Science, Leiden University Medical Center, Leiden, Netherlands. |
| المصدر: | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery [Eur J Cardiothorac Surg] 2023 Oct 04; Vol. 64 (4). |
| نوع المنشور: | Systematic Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: Germany NLM ID: 8804069 Publication Model: Print Cited Medium: Internet ISSN: 1873-734X (Electronic) Linking ISSN: 10107940 NLM ISO Abbreviation: Eur J Cardiothorac Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2012-: Oxford, England : Oxford University Press Original Publication: [Berlin] : Springer International ; [Secaucus, NJ, USA : Springer-Verlag New York Inc., distributor, c1987- |
| مواضيع طبية MeSH: | Propensity Score*, Humans ; Observational Studies as Topic |
| مستخلص: | Objectives: It is unknown which confounding adjustment methods are currently used in the field of cardiothoracic surgery and whether these are appropriately applied. The aim of this study was to systematically evaluate the quality of conduct and reporting of confounding adjustment methods in observational studies on cardiothoracic interventions. Methods: A systematic review was performed, which included all observational studies that compared different interventions and were published between 1 January and 1 July 2022, in 3 European and American cardiothoracic surgery journals. Detailed information on confounding adjustment methods was extracted and subsequently described. Results: Ninety-two articles were included in the analysis. Outcome regression (n = 49, 53%) and propensity score (PS) matching (n = 44, 48%) were most popular (sometimes used in combination), whereas 11 (12%) studies applied no method at all. The way of selecting confounders was not reported in 42 (46%) of the studies, solely based on previous literature or clinical knowledge in 14 (16%), and (partly) data-driven in 25 (27%). For the studies that applied PS matching, the matched cohorts comprised on average 46% of the entire study population (range 9-82%). Conclusions: Current reporting of confounding adjustment methods is insufficient in a large part of observational studies on cardiothoracic interventions, which makes quality judgement difficult. Appropriate application of confounding adjustment methods is crucial for causal inference on optimal treatment strategies for clinical practice. Reporting on these methods is an important aspect of this, which can be improved. (© The Author(s) 2023. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery.) |
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| فهرسة مساهمة: | Keywords: Cardiothoracic surgery; Confounding methods; Epidemiology; Intervention; Observational; Propensity score |
| تواريخ الأحداث: | Date Created: 20230728 Date Completed: 20231027 Latest Revision: 20231206 |
| رمز التحديث: | 20231215 |
| مُعرف محوري في PubMed: | PMC10597584 |
| DOI: | 10.1093/ejcts/ezad271 |
| PMID: | 37505476 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-734X |
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| DOI: | 10.1093/ejcts/ezad271 |