دورية أكاديمية
A novel parameter for the prediction of rupture risk of cerebral aneurysms based on morphology.
| العنوان: | A novel parameter for the prediction of rupture risk of cerebral aneurysms based on morphology. |
|---|---|
| المؤلفون: | Maramkandam EB; Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India., Sudhir BJ; Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India.; Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India., Kannath SK; Department of Imaging Sciences and Interventional Radiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India., Patnaik BSV; Department of Applied Mechanics, Indian Institute of Technology Madras, Chennai, Tamil Nadu, India. |
| المصدر: | Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine [Proc Inst Mech Eng H] 2023 Sep; Vol. 237 (9), pp. 1091-1101. Date of Electronic Publication: 2023 Aug 02. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Sage Country of Publication: England NLM ID: 8908934 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2041-3033 (Electronic) Linking ISSN: 09544119 NLM ISO Abbreviation: Proc Inst Mech Eng H Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Dec. 2010- : London : Sage Original Publication: [London ; Birmingham, Ala. : Published for the Institution by Mechanical Engineering Publications Ltd.], c1989- |
| مواضيع طبية MeSH: | Intracranial Aneurysm* , Aneurysm, Ruptured*, Humans ; Hemodynamics |
| مستخلص: | Neurosurgeons often encounter dilemmas in the clinical management of cerebral aneurysms owing to an uncertainty of their rupture status and rupture risk. This study evaluates the influence of natural frequency of an aneurysm, as a novel morphological parameter to understand and analyze rupture status and risk prediction. In this work, we employ the natural frequency of 20 idealized and 50 patient specific aneurysms. The natural frequency of patient specific aneurysms is then compared against their rupture status. A strong correlation was observed between various morphological indicators and natural frequency for ideal and patient specific geometries. A statistical analysis with both Mann Whitney U test and T -test for rupture status against natural frequency has given a p -value less than 0.01 indicating a strong correlation between them. The correlation of morphological parameters with natural frequency from Pearson correlation coefficient and T -test suggests a holistic reflection of their effects on the natural frequency of an aneurysm. Thus, natural frequency could be a good indicator to discern the rupture potential of an aneurysm. The correlation between rupture status and natural frequency makes it a novel parameter that can differentiate between ruptured and unruptured patient specific aneurysms. |
| فهرسة مساهمة: | Keywords: Aneurysm; biomechanics; cerebral circulation; cerebral disorders; hemodynamics; natural frequency; rupture prediction |
| تواريخ الأحداث: | Date Created: 20230803 Date Completed: 20230912 Latest Revision: 20230912 |
| رمز التحديث: | 20240829 |
| DOI: | 10.1177/09544119231188697 |
| PMID: | 37533293 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2041-3033 |
|---|---|
| DOI: | 10.1177/09544119231188697 |