دورية أكاديمية
Real life use of prostacyclin analog (iloprost), a multi-centric survey data from the Scleroderma study group Emilia Romagna (Sclero-RER) and review of the literature.
| العنوان: | Real life use of prostacyclin analog (iloprost), a multi-centric survey data from the Scleroderma study group Emilia Romagna (Sclero-RER) and review of the literature. |
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| المؤلفون: | Magnani L; a:1:{s:5:'en_US';s:40:'Arcispedale S. Maria Nuova Reggio Emilia';}. magnani.l@gmail.com., Ariani A; atendoro@gmail.com., Lo Monaco A; lmnndr@unife.it., Girelli F; francesco.girelli@auslromagna.it., Spinella A; amelia.spinella@gmail.com., Lumetti F; fedelumetti@gmail.com., Reta M; massimo.reta@ausl.bologna.it., Arrigoni E; e.arrigoni@ausl.pc.it., Ursini F; francesco.ursini@ior.it., Bezzi A; alessandra.bezzi@auslromagna.it., Cataleta P; pierluigi.cataleta@auslromagna.it., Montaguti L; luca.montaguti@auslromagna.it., Trevisani M; marica.trevisani@aosp.bo.it., Colina M; m.colina@ausl.imola.bo.it., Bernardi S; siberna@yahoo.it., De Pinto M; marcodepinto1993@gmail.com., Galoppini G; giorgio.galoppini@edu.unife.it., Testoni S; sofy.testoni@live.it., Becciolini A; beccio@yahoo.it., Pignataro F; francesca.pignataro@ausl.bologna.it., Ciaffi J; jacopo.ciaffi@ior.it., Bravi E; E.Bravi@ausl.pc.it., Focherini M; m.focherini@alice.it., Moscatelli S; heila.moscatelli@auslromagna.it., Sambo P; paola.sambo@auslromagna.it., Fusconi M; marco.fusconi@aosp.bo.it., Corvaglia S; s.corvaglia@ausl.imola.bo.it., Bajocchi G; gianluigi.bajocchi@ausl.re.it., Conti D; contidaniele@hotmail.it., Salvarani C; Carlo.Salvarani@ausl.re.it., Giuggioli D; dilia.giuggioli@unimore.it. |
| المصدر: | Acta bio-medica : Atenei Parmensis [Acta Biomed] 2023 Aug 03; Vol. 94 (4), pp. e2023148. Date of Electronic Publication: 2023 Aug 03. |
| نوع المنشور: | Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mattioli 1885 Country of Publication: Italy NLM ID: 101295064 Publication Model: Electronic Cited Medium: Internet ISSN: 2531-6745 (Electronic) Linking ISSN: 03924203 NLM ISO Abbreviation: Acta Biomed Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2003- : Fidenza, Parma : Mattioli 1885 Original Publication: Parma, Italy : Ateneo parmense, [2002]- |
| مواضيع طبية MeSH: | Iloprost*/therapeutic use , Iloprost*/adverse effects , Scleroderma, Systemic*/drug therapy , Scleroderma, Systemic*/chemically induced, Humans ; Epoprostenol/therapeutic use ; Prostaglandins I ; Wound Healing ; Surveys and Questionnaires |
| مستخلص: | Background and Aim: Iloprost is recommend worldwide for the treatment of RP and the healing of DUs. The aim of this study is to report the regimens of Iloprost administered in different rheumatological centers within the same regional Health System Methods: A questionnaire exploring different items related to the use of Iloprost was developed and reviewed by three expert rheumatologists. The questionnaire was distributed as an online survey to all local SSc referral centers in Emilia-Romagna (Italy). Data are reported as percentage or median with interquartile range (IQR), as appropriate. An updated review of world literature on this topic was also carried out. Results: All the invited centers completed the survey. There were both local (8) and university hospitals (4). The majority (58%) had a rheumatologist as head physician. All centers used Iloprost: a single monthly administration was the most common treatment (75%). The cycle lasted 1 [IQR 1-2] days with a 0.5-2.0 ng/Kg/min dose according to the drug tolerance of the patients. There were overall 68 spots (beds, reclining armchair, or simple armchair); 2.0 [1.5-4.0] patients were able to receive Iloprost at the same time. University Hospitals had more physicians at their disposal than local hospitals but less paramedic personnel (respectively: 1.8 vs 1.2 physicians, 1.5 vs 2.1 nurses). Conclusions: These observations were in line with the majority of previous studies reporting different regimens, comparing similar (but not identical) dose and schedule administration, however, despite differences being at times substantial, no standard infusion method is yet available. |
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| المشرفين على المادة: | JED5K35YGL (Iloprost) DCR9Z582X0 (Epoprostenol) 0 (Prostaglandins I) |
| تواريخ الأحداث: | Date Created: 20230804 Date Completed: 20230807 Latest Revision: 20230823 |
| رمز التحديث: | 20230823 |
| مُعرف محوري في PubMed: | PMC10440762 |
| DOI: | 10.23750/abm.v94i4.14317 |
| PMID: | 37539603 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2531-6745 |
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| DOI: | 10.23750/abm.v94i4.14317 |