دورية أكاديمية
Preliminary evaluation of reference intervals for a point-of-care viscoelastic coagulation monitor (VCM Vet) in healthy adult horses.
| العنوان: | Preliminary evaluation of reference intervals for a point-of-care viscoelastic coagulation monitor (VCM Vet) in healthy adult horses. |
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| المؤلفون: | Bishop RC; Department of Veterinary Clinical Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, USA., Kemper AM; Department of Veterinary Clinical Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, USA., Burges JW; William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, Davis, California, USA., Jandrey KE; William R. Pritchard Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis, Davis, California, USA., Wilkins PA; Department of Veterinary Clinical Medicine, University of Illinois Urbana-Champaign, Urbana, Illinois, USA. |
| المصدر: | Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) [J Vet Emerg Crit Care (San Antonio)] 2023 Sep-Oct; Vol. 33 (5), pp. 540-548. Date of Electronic Publication: 2023 Aug 10. |
| نوع المنشور: | Observational Study, Veterinary; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Blackwell Country of Publication: United States NLM ID: 101152804 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4431 (Electronic) Linking ISSN: 14764431 NLM ISO Abbreviation: J Vet Emerg Crit Care (San Antonio) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: <2005-> : Malden, MA : Blackwell Original Publication: San Antonio, TX : Veterinary Emergency & Critical Care Society, [2001]- |
| مواضيع طبية MeSH: | Thrombelastography*/veterinary , Point-of-Care Systems*, Humans ; Horses ; Animals ; Blood Coagulation ; Blood Coagulation Tests/veterinary ; Hemostasis |
| مستخلص: | Objective: To evaluate a point-of-care viscoelastic coagulation monitor (VCM Vet) for use in horses by assessing variability between devices and establish reference intervals (RIs) for healthy adult horses. Design: Prospective observational study. Setting: Two university teaching hospitals. Animals: Healthy adult horses (n = 68). Interventions: None. Measurements and Main Results: Blood collected by direct jugular venipuncture was applied directly from the syringe into 2 VCM Vet cassettes to establish coefficients of variation (CVs) and RIs for reported parameters of clotting time (CT), clot formation time (CFT), alpha angle, amplitude at 10 and 20 minutes, maximum clot firmness, and lysis index at 30 and 45 minutes. CVs for each parameter were within clinical tolerance. There was a significant difference in CT between institutions (P < 0.001). Differences in CV were found between institutions for CT (P = 0.003) and CFT (P = 0.01). Healthy horse RIs were calculated for the overall data set and each individual institution. Calculated RIs were as follows: CT, 255.6-1233.9 seconds; CFT, 89.4-581 seconds; alpha angle, 11.4-53.6°; maximum clot firmness, 18-37.7; lysis index at 30 minutes, 97.3%-102.1%; lysis index at 45 minutes, 80.8%-103.3%; amplitude at 10 minutes, 8.7-28.3; and amplitude at 20 minutes, 17.4-35.7. Conclusions: VCM Vet is a repeatable and practical option for rapid point-of-care assessment of hemostasis in horses but has a wide RI and is susceptible to variability. Establishment of institution-specific RIs is recommended. (© Veterinary Emergency and Critical Care Society 2023.) |
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| فهرسة مساهمة: | Keywords: clotting time; coagulopathy; equine; fibrin; hemostasis |
| تواريخ الأحداث: | Date Created: 20230810 Date Completed: 20231102 Latest Revision: 20231102 |
| رمز التحديث: | 20240628 |
| DOI: | 10.1111/vec.13317 |
| PMID: | 37561043 |
| قاعدة البيانات: | MEDLINE |
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