دورية أكاديمية
Autoimmune diseases and their prevalence in Saudi Arabian patients with type 1 diabetes mellitus.
| العنوان: | Autoimmune diseases and their prevalence in Saudi Arabian patients with type 1 diabetes mellitus. |
|---|---|
| المؤلفون: | Mohammedsaeed WM; From the Department of Medical Laboratory Technology (Mohammedsaeed), Faculty of Applied Medical Science, Taibah University, and from the Department of Endocrinology and Diabetes Center (Alghamdi), King Fahad Hospital, Al-Madinah Al-Munawwarah, Kingdom of Saudi Arabia., Alghamdi ZJ; From the Department of Medical Laboratory Technology (Mohammedsaeed), Faculty of Applied Medical Science, Taibah University, and from the Department of Endocrinology and Diabetes Center (Alghamdi), King Fahad Hospital, Al-Madinah Al-Munawwarah, Kingdom of Saudi Arabia. |
| المصدر: | Saudi medical journal [Saudi Med J] 2023 Aug; Vol. 44 (8), pp. 751-760. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Country of Publication: Saudi Arabia NLM ID: 7909441 Publication Model: Print Cited Medium: Internet ISSN: 1658-3175 (Electronic) Linking ISSN: 03795284 NLM ISO Abbreviation: Saudi Med J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Riyadh : Medical Services Department, Saudi Arabian Armed Forces, Ministry Of Defence And Aviation Original Publication: Riyadh, Saudi Arabia, Riyadh Al-Kharj Hospital Programme. |
| مواضيع طبية MeSH: | Diabetes Mellitus, Type 1*/epidemiology , Thyroiditis, Autoimmune* , Celiac Disease*/epidemiology , Autoimmune Diseases*/epidemiology , Hashimoto Disease* , Cardiovascular Diseases*, Child ; Adult ; Adolescent ; Humans ; Female ; Male ; Saudi Arabia/epidemiology ; Retrospective Studies ; Prevalence |
| مستخلص: | Objectives: To evaluate the prevalence of autoimmune disorders among young and adult populations diagnosed with type 1 diabetes mellitus (T1DM) in Al-Madinah Al-Munawarah, Saudi Arabia, and assess the potential impact of these conditions on other comorbidities. Methods: A retrospective, descriptive study examined autoimmune disorders in T1DM youth and adults. A total of 2258 verified T1DMs were tested. Analyzed hospital and laboratory data. Autoimmune T1DM was investigated clinically and laboratory. Results: A total of 2258 T1DM adults, adolescents, and children were investigated; 500 (22.2%) were under 12, 540 (23.9%) were 13-17, and 1218 (53.9%) were 18 plus. Autoimmune with T1DM was 67.4%. Gender and age affect prevalence. 25.7% of adult females had autoimmune thyroiditis. Children and adolescents have greater rates of celiac disease than adults of both genders. Adrenal insufficiency was more frequent in adults. Adult males had 28.5% polyglandular autoimmune diseases, and women had 19.7%. Type 1 DM and other autoimmune illnesses increase the risk of nephropathy, CVD, and hypoglycemia. Bloodstream biomarkers linked to these disorders corroborate this. Conclusion: Autoimmune diseases in Saudi patients with T1DM exhibited specificity with respect to gender and age. Al-Madinah Al-Munawwarah have a heightened prevalence of autoimmune diseases among young individuals diagnosed with T1DM, such as celiac disease and autoimmune thyroiditis. Conversely, older individuals in the region have been observed to exhibit a greater incidence of adrenal failure and polyglandular autoimmune disorders. Autoimmune diseases that result in nephropathy, CVD, and hypoglycemia are highly prevalent based on biomarker levels. (Copyright: © Saudi Medical Journal.) |
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| فهرسة مساهمة: | Keywords: Saudi Arabia; adrenal insufficiency; autoimmune disease; autoimmune thyroid; celiac disease; polyglandular autoimmune syndromes; type 1 diabetes |
| تواريخ الأحداث: | Date Created: 20230815 Date Completed: 20230817 Latest Revision: 20231216 |
| رمز التحديث: | 20231216 |
| مُعرف محوري في PubMed: | PMC10425616 |
| DOI: | 10.15537/smj.2023.44.8.20230240 |
| PMID: | 37582563 |
| قاعدة البيانات: | MEDLINE |
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