Four New Stilbene Derivatives Isolated from Gnetum latifolium var. funiculare Markgr. and Their Inhibition of NO Production in LPS-activated RAW264.7 Cells.

التفاصيل البيبلوغرافية
العنوان:	Four New Stilbene Derivatives Isolated from Gnetum latifolium var. funiculare Markgr. and Their Inhibition of NO Production in LPS-activated RAW264.7 Cells.
المؤلفون:	Thuy TT; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam., Hoa NTT; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.; Vietnam National University of Agriculture, Trau Quy, Gia Lam, Hanoi, 10072, Vietnam., Linh NTT; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam., Cham BT; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam., Anh NTH; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.; Institute of Chemistry, Vietnam Academy of Science and Technology (VAST), 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam., Hiep NT; National Institute of Medicinal Materials, 3B Quang Trung, Hoan Kiem, 10072, Vietnam., Adorisio S; Master in musculoskeletal and rheumatology physiotherapy, Department of Medicine and Surgery, University of Perugia, Piazzale Severi, S. Andreadelle Fratte, 06132, Perugia, Italy., Delfino DV; Master in musculoskeletal and rheumatology physiotherapy, Department of Medicine and Surgery, University of Perugia, Piazzale Severi, S. Andreadelle Fratte, 06132, Perugia, Italy., Bang NA; Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam E-mail: s., Tai BH; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.; Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam E-mail: s., Kiem PV; Graduate University of Science and Technology, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam.; Institute of Marine Biochemistry, VAST, 18 Hoang Quoc Viet, Cau Giay, Hanoi, 10072, Vietnam E-mail: s.
المصدر:	Chemistry & biodiversity [Chem Biodivers] 2023 Oct; Vol. 20 (10), pp. e202301166. Date of Electronic Publication: 2023 Oct 02.
نوع المنشور:	Journal Article
اللغة:	English
بيانات الدورية:	Publisher: Verlag Helvetica Chimica Acta Country of Publication: Switzerland NLM ID: 101197449 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1612-1880 (Electronic) Linking ISSN: 16121872 NLM ISO Abbreviation: Chem Biodivers Subsets: MEDLINE
أسماء مطبوعة:	Original Publication: Zürich, Switzerland : Hoboken, NJ : Verlag Helvetica Chimica Acta ; Distributed in the USA by Wiley, c2004-
مستخلص:	Gnetum latifolium var. funiculare Markgr. is a medicinal plant and widely distributed in mountainous areas of Vietnam. Phytochemical investigation on the trunks of this plant afforded eight stilbene derivatives (1-8) including for new compounds (1-4). Their structures were determined based on extensive analyses of HR-ESI-MS, 1D and 2D NMR spectra. Among the isolates, compounds 1-3 showed moderate NO production inhibition in LPS-activated RAW264.7 cells with the IC 50 values ranging from 46.81 to 68.10 μM, compounds 4 and 6 showed weak effects with the IC 50 values of 96.57 and 79.46 μM, respectively, compared to that of the positive control compound, dexamethasone (IC 50 14.20 μM). (© 2023 Wiley-VHCA AG, Zurich, Switzerland.)
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معلومات مُعتمدة:	04/2022/TN Vietnam National Foundation for Science and Technology Development
فهرسة مساهمة:	Keywords: Gnetum latifolium var. funiculare; gnetumlatioside A; gnetumlatioside B; gnetumlatioside C; gnetumlatioside D
تواريخ الأحداث:	Date Created: 20230817 Latest Revision: 20231020
رمز التحديث:	20231021
DOI:	10.1002/cbdv.202301166
PMID:	37591796
قاعدة البيانات:	MEDLINE

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تدمد:	1612-1880
DOI:	10.1002/cbdv.202301166