دورية أكاديمية
أعرض في EDS

Factors associated with Alzheimer's disease prevalence and mortality in Brazil-An ecological study.

التفاصيل البيبلوغرافية
العنوان: Factors associated with Alzheimer's disease prevalence and mortality in Brazil-An ecological study.
المؤلفون: Bastos M; Laboratório de Neurociência e Comportamento, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.; Cline Research Center, Curitiba, PR, Brazil., da Silva MP; Faculty of Medicine, Federal University of Rio Grande, Rio Grande, RS, Brazil., da Silva D; Departamento de Enfermagem, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil., Negrão GN; Associação de Estudos, Pesquisa e Assistência as Pessoas com Doença de Alzheimer, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil., Schumanski G; Profnit, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil., da Silva WCFN; Associação de Estudos, Pesquisa e Assistência as Pessoas com Doença de Alzheimer, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil., Bonini JS; Laboratório de Neurociência e Comportamento, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.; Associação de Estudos, Pesquisa e Assistência as Pessoas com Doença de Alzheimer, Universidade Estadual do Centro-Oeste, Guarapuava, PR, Brazil.
المصدر: PloS one [PLoS One] 2023 Aug 21; Vol. 18 (8), pp. e0283936. Date of Electronic Publication: 2023 Aug 21 (Print Publication: 2023).
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
أسماء مطبوعة: Original Publication: San Francisco, CA : Public Library of Science
مواضيع طبية MeSH: Alzheimer Disease*/epidemiology, Aged ; Humans ; Brazil/epidemiology ; Prevalence ; Food, Processed ; Income
مستخلص: A few epidemiological studies are evaluating the prevalence and mortality rates of Alzheimer's disease, with no one using a nationwide sample of Brazilian elderlies. This study aims to calculate the prevalence of Alzheimer's disease and investigate possible associations with sociodemographic and lifestyle factors and the presence of diseases non-communicable, and the prevalence and mortality for all Brazilian state capitals. This is an ecological design study made with secondary public data provided by the Ministry of Health. Prevalence rates were calculated based on the analysis of the dispensing of Alzheimer's disease-specific drugs. Correlation analyzes were performed between rates and factors, and a multiple linear regression analysis was used to analyze possible associations between variables, controlled for each other. AD prevalence was 313/100,000. Prevalence rates were positively associated with primary health care coverage factors and negatively associated with ultra-processed food consumption and physical activity levels. AD mortality was 98/100,000. Mortality rates were positively associated with the proportion of obese elderly and elderly living on up to half the minimum wage and were inversely associated with the proportion of elderly with diabetes factors. We found positive and negative associations of sociodemographic, behavioral and diabetes indicators with Alzheimer's disease prevalence and mortality, which provide data that can be investigated by studies with different designs.
Competing Interests: NO authors have competing interests.
(Copyright: © 2023 Bastos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
References: Neurology. 2014 Mar 25;82(12):1045-50. (PMID: 24598707)
Dement Neuropsychol. 2014 Oct-Dec;8(4):317-322. (PMID: 29213920)
Arch Neurol. 2011 Jun;68(6):743-52. (PMID: 21670398)
Handb Clin Neurol. 2019;167:139-148. (PMID: 31753130)
Brain Pathol. 2019 Jan;29(1):3-17. (PMID: 30106209)
Rev Bras Epidemiol. 2021 Apr 14;24:e210018. (PMID: 33886873)
Lancet Neurol. 2014 Aug;13(8):788-94. (PMID: 25030513)
Alzheimer Dis Assoc Disord. 2010 Apr-Jun;24(2):126-30. (PMID: 19571736)
Dement Neuropsychol. 2014 Oct-Dec;8(4):339-344. (PMID: 29213923)
Arch Neurol. 2010 Apr;67(4):428-33. (PMID: 20385908)
Alzheimers Dement (Amst). 2020 Aug 11;12(1):e12063. (PMID: 32793798)
Cad Saude Publica. 2015 Aug;31(8):1623-35. (PMID: 26375642)
J Alzheimers Dis. 2017;59(3):815-849. (PMID: 28697569)
Alzheimer Dis Assoc Disord. 2004 Oct-Dec;18(4):241-6. (PMID: 15592138)
Int J Mol Sci. 2020 Apr 30;21(9):. (PMID: 32365816)
J Geriatr Psychiatry Neurol. 2009 Sep;22(3):181-7. (PMID: 19307320)
Alzheimers Dement. 2020 Mar 10;:. (PMID: 32157811)
Appetite. 2013 Apr;63:119-28. (PMID: 23291218)
J Alzheimers Dis. 2020;73(3):1157-1166. (PMID: 31884487)
Neurobiol Aging. 2010 Aug;31(8):1326-39. (PMID: 20570405)
Psychiatry Clin Neurosci. 2002 Feb;56(1):71-5. (PMID: 11929573)
Indian J Psychiatry. 2009 Jan;51 Suppl 1:S93-7. (PMID: 21416026)
Alzheimers Res Ther. 2020 Sep 26;12(1):116. (PMID: 32979927)
Lancet. 2015 Jan 31;385(9966):418-9. (PMID: 25706975)
Alzheimers Dement. 2013 Jan;9(1):63-75.e2. (PMID: 23305823)
Neurologia. 2017 Oct;32(8):523-532. (PMID: 27130306)
Neuroreport. 2011 Jan 5;22(1):10-4. (PMID: 21539003)
BMC Psychol. 2018 May 21;6(1):23. (PMID: 29784047)
Am J Alzheimers Dis Other Demen. 2018 Feb;33(1):12-19. (PMID: 28945135)
Curr Psychiatry Rep. 2016 Sep;18(9):85. (PMID: 27481112)
Int Psychogeriatr. 2008 Apr;20(2):394-405. (PMID: 17559708)
JAMA Netw Open. 2021 Aug 2;4(8):e2120398. (PMID: 34379124)
J Alzheimers Dis. 2019 Aug 12;71(2):513-523. (PMID: 31424411)
Neurol Neurochir Pol. 2021;55(5):418-428. (PMID: 34355790)
Lancet. 2016 Oct 8;388(10053):1459-1544. (PMID: 27733281)
تواريخ الأحداث: Date Created: 20230821 Date Completed: 20230823 Latest Revision: 20230828
رمز التحديث: 20231215
مُعرف محوري في PubMed: PMC10441790
DOI: 10.1371/journal.pone.0283936
PMID: 37603571
قاعدة البيانات: MEDLINE
الوصف
تدمد:1932-6203
DOI:10.1371/journal.pone.0283936