دورية أكاديمية
McKittrick-Wheelock syndrome: chronic diarrhea and electrolyte abnormalities due to a large rectal polyp with endoscopic management.
| العنوان: | McKittrick-Wheelock syndrome: chronic diarrhea and electrolyte abnormalities due to a large rectal polyp with endoscopic management. |
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| المؤلفون: | Peress S; Department of Internal Medicine, Oregon Health and Science University, Portland, Oregon, USA., Bonilla C; School of Medicine, Oregon Health and Science University, Portland, Oregon, USA., Yoo ER; Department of Internal Medicine, Oregon Health and Science University, Portland, Oregon, USA; Division of Gastroenterology and Hepatology, Oregon Health and Science University, Portland, Oregon, USA., Brinkerhoff B; Department of Internal Medicine, Oregon Health and Science University, Portland, Oregon, USA; Department of Pathology and Laboratory Medicine, Oregon Health and Science University, Portland, Oregon, USA., Bakis G; Department of Internal Medicine, Oregon Health and Science University, Portland, Oregon, USA; Division of Gastroenterology and Hepatology, Oregon Health and Science University, Portland, Oregon, USA., Yu J; Department of Internal Medicine, Oregon Health and Science University, Portland, Oregon, USA; Division of Gastroenterology and Hepatology, Oregon Health and Science University, Portland, Oregon, USA. |
| المصدر: | Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Feb; Vol. 99 (2), pp. 298-300. Date of Electronic Publication: 2023 Sep 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Mosby Yearbook Country of Publication: United States NLM ID: 0010505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6779 (Electronic) Linking ISSN: 00165107 NLM ISO Abbreviation: Gastrointest Endosc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: St Louis, Mo : Mosby Yearbook Original Publication: Denver. |
| مواضيع طبية MeSH: | Water-Electrolyte Imbalance*/etiology , Rectal Neoplasms*/complications , Rectal Neoplasms*/surgery , Adenoma, Villous*/complications , Adenoma, Villous*/surgery, Humans ; Diarrhea/etiology ; Endoscopy ; Electrolytes |
| مستخلص: | Competing Interests: Disclosure All authors disclosed no financial relationships. Commentary This case illustrates a patient with the extremely rare McKittrick-Wheelock syndrome. Readers can be forgiven for never having heard of this syndrome. The syndrome involves large villous adenomas that secrete mucin rich in electrolytes that can lead to prerenal kidney injury as well as dehydration from secretory diarrhea. The fact that this could all be caused by a polyp is counterintuitive but nonetheless true. The mainstay of therapy is to remove the offending adenoma, either by endoscopy or surgery, as was performed here. The lesions that cause this syndrome can be very large, as was the case in this patient. Physicians unfamiliar with the syndrome may not make the connection between the patient’s diarrhea and kidney injury and the adenoma. Still, prompt recognition of this constellation of findings can produce an excellent outcome and avoid significant adverse events for the patient. Douglas G. Adler, MD, FASGE, GIE Editor-in-Chief Amy Tyberg, MD, FASGE, FACG, Associate Editor for Focal Points |
| المشرفين على المادة: | 0 (Electrolytes) |
| تواريخ الأحداث: | Date Created: 20230924 Date Completed: 20240122 Latest Revision: 20240524 |
| رمز التحديث: | 20240525 |
| DOI: | 10.1016/j.gie.2023.09.016 |
| PMID: | 37742777 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1097-6779 |
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| DOI: | 10.1016/j.gie.2023.09.016 |