دورية أكاديمية
أعرض في EDS

MR1 antigen presentation to MAIT cells and other MR1-restricted T cells.

التفاصيل البيبلوغرافية
العنوان: MR1 antigen presentation to MAIT cells and other MR1-restricted T cells.
المؤلفون: McWilliam HEG; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia. hamish.mcwilliam@unimelb.edu.au.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia. hamish.mcwilliam@unimelb.edu.au., Villadangos JA; Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Parkville, Victoria, Australia. j.villadangos@unimelb.edu.au.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, Victoria, Australia. j.villadangos@unimelb.edu.au.
المصدر: Nature reviews. Immunology [Nat Rev Immunol] 2024 Mar; Vol. 24 (3), pp. 178-192. Date of Electronic Publication: 2023 Sep 29.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101124169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1474-1741 (Electronic) Linking ISSN: 14741733 NLM ISO Abbreviation: Nat Rev Immunol Subsets: MEDLINE
أسماء مطبوعة: Original Publication: London, UK : Nature Pub. Group, [c2001-
مواضيع طبية MeSH: Antigen Presentation* , Mucosal-Associated Invariant T Cells*, Humans ; Minor Histocompatibility Antigens ; Histocompatibility Antigens Class I ; Antigens
مستخلص: MHC antigen presentation plays a fundamental role in adaptive and semi-invariant T cell immunity. Distinct MHC molecules bind antigens that differ in chemical structure, origin and location and present them to specialized T cells. MHC class I-related protein 1 (MR1) presents a range of small molecule antigens to MR1-restricted T (MR1T) lymphocytes. The best studied MR1 ligands are derived from microbial metabolism and are recognized by a major class of MR1T cells known as mucosal-associated invariant T (MAIT) cells. Here, we describe the MR1 antigen presentation pathway: the known types of antigens presented by MR1, the location where MR1-antigen complexes form, the route followed by the complexes to the cell surface, the mechanisms involved in termination of MR1 antigen presentation and the accessory cellular proteins that comprise the MR1 antigen presentation machinery. The current road map of the MR1 antigen presentation pathway reveals potential strategies for therapeutic manipulation of MR1T cell function and provides a foundation for further studies that will lead to a deeper understanding of MR1-mediated immunity.
(© 2023. Springer Nature Limited.)
References: Sci Rep. 2020 Oct 6;10(1):16604. (PMID: 33024151)
Biochem Biophys Res Commun. 1997 Sep 29;238(3):697-702. (PMID: 9325151)
Biol Chem. 2015 Sep;396(9-10):1059-72. (PMID: 25781678)
PLoS One. 2019 Sep 27;14(9):e0223025. (PMID: 31560732)
Immunogenetics. 2013 Feb;65(2):115-24. (PMID: 23229473)
Nat Immunol. 2016 May;17(5):531-7. (PMID: 27043408)
Nature. 1994 Sep 15;371(6494):250-2. (PMID: 8078585)
Nat Immunol. 2022 Dec;23(12):1714-1725. (PMID: 36411380)
Biochem Biophys Res Commun. 2011 Aug 5;411(3):632-6. (PMID: 21777569)
Nat Chem Biol. 2022 Aug;18(8):859-868. (PMID: 35725941)
Immunology. 2017 Oct;152(2):232-242. (PMID: 28518215)
Curr Opin Immunol. 2017 Jun;46:97-102. (PMID: 28528220)
J Exp Med. 2008 May 12;205(5):1201-11. (PMID: 18443227)
Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1828-33. (PMID: 9050864)
Annu Rev Immunol. 2015;33:169-200. (PMID: 25493333)
EMBO J. 2004 Mar 24;23(6):1267-78. (PMID: 15029241)
FEBS J. 2007 Mar;274(6):1552-66. (PMID: 17313651)
J Virol. 2011 Aug;85(16):8093-104. (PMID: 21653669)
EMBO J. 1996 Apr 1;15(7):1495-506. (PMID: 8612572)
Nature. 2017 Nov 23;551(7681):525-528. (PMID: 29107940)
Front Immunol. 2020 Apr 28;11:751. (PMID: 32411144)
Trends Immunol. 2016 Nov;37(11):724-737. (PMID: 27614798)
Nat Commun. 2019 May 21;10(1):2243. (PMID: 31113973)
Cell Rep. 2015 Feb 17;10(6):968-982. (PMID: 25683719)
Nat Immunol. 2010 Aug;11(8):701-8. (PMID: 20581831)
J Exp Med. 1993 Jul 1;178(1):1-16. (PMID: 8391057)
Immunol Cell Biol. 2018 Jul;96(6):564-572. (PMID: 29363173)
FEBS Lett. 2002 Oct 2;529(1):49-53. (PMID: 12354612)
Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3465-70. (PMID: 23401559)
Proc Natl Acad Sci U S A. 2020 May 12;117(19):10465-10475. (PMID: 32341160)
Nucleic Acids Res. 2020 Jan 8;48(D1):D948-D955. (PMID: 31667505)
Cold Spring Harb Perspect Biol. 2013 Nov 01;5(11):a016790. (PMID: 24186068)
ACS Chem Biol. 2020 Feb 21;15(2):437-445. (PMID: 31909966)
Annu Rev Biochem. 2009;78:857-902. (PMID: 19317650)
HLA. 2021 Dec;98(6):509-516. (PMID: 34351076)
J Virol. 2001 May;75(10):4878-88. (PMID: 11312359)
Nature. 1990 Aug 2;346(6283):476-80. (PMID: 2198471)
J Immunol. 2002 Feb 15;168(4):1538-41. (PMID: 11823478)
J Immunol. 2001 Jan 15;166(2):1016-27. (PMID: 11145681)
J Biol Chem. 2000 May 5;275(18):13713-20. (PMID: 10788491)
Immunogenetics. 2016 Aug;68(8):537-48. (PMID: 27393664)
Nat Rev Mol Cell Biol. 2018 May;19(5):313-326. (PMID: 29410531)
Curr Opin Immunol. 2021 Jun;70:48-56. (PMID: 33689959)
J Exp Med. 2013 Oct 21;210(11):2305-20. (PMID: 24101382)
Nat Immunol. 2005 Jan;6(1):107-13. (PMID: 15592474)
Mucosal Immunol. 2013 Jan;6(1):35-44. (PMID: 22692454)
Immunity. 2001 Jun;14(6):739-49. (PMID: 11420044)
Allergy. 2021 Oct;76(10):3155-3170. (PMID: 34185885)
Proc Natl Acad Sci U S A. 2009 May 19;106(20):8290-5. (PMID: 19416870)
Annu Rev Cell Dev Biol. 2008;24:343-68. (PMID: 18729726)
PLoS Pathog. 2016 Mar 31;12(3):e1005524. (PMID: 27031111)
Immunity. 2016 Jan 19;44(1):32-45. (PMID: 26795251)
Front Immunol. 2020 Aug 27;11:1961. (PMID: 32973800)
J Cell Biol. 2008 Jan 28;180(2):375-87. (PMID: 18227281)
Cancer Immunol Immunother. 2022 May;71(5):1259-1273. (PMID: 34854949)
Nat Rev Immunol. 2004 Feb;4(2):123-32. (PMID: 15040585)
Immunol Cell Biol. 2018 May;96(5):507-525. (PMID: 29437263)
Science. 2020 Sep 25;369(6511):. (PMID: 32973005)
J Clin Invest. 2018 May 1;128(5):1919-1936. (PMID: 29629900)
Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):86-91. (PMID: 12518055)
J Immunol. 2003 Jun 15;170(12):6090-8. (PMID: 12794138)
Nat Commun. 2022 Nov 14;13(1):6948. (PMID: 36376329)
Trends Immunol. 2017 Sep;38(9):679-689. (PMID: 28688841)
PLoS Pathog. 2013;9(10):e1003681. (PMID: 24130485)
Nat Immunol. 2007 Aug;8(8):873-81. (PMID: 17603487)
Eur J Immunol. 2016 Jul;46(7):1600-14. (PMID: 27105778)
PLoS One. 2014 May 14;9(5):e97515. (PMID: 24828674)
Curr Opin Immunol. 2018 Jun;52:108-113. (PMID: 29754112)
PLoS One. 2013 Aug 12;8(8):e72050. (PMID: 23951282)
J Exp Med. 1999 Jun 21;189(12):1907-21. (PMID: 10377186)
Nat Immunol. 2017 Apr;18(4):402-411. (PMID: 28166217)
Mucosal Immunol. 2018 Jul;11(4):1060-1070. (PMID: 29743612)
J Exp Med. 2022 Sep 5;219(9):. (PMID: 36018322)
Mucosal Immunol. 2017 Jan;10(1):58-68. (PMID: 27143301)
J Cell Biol. 2002 Feb 18;156(4):653-64. (PMID: 11839770)
Science. 2019 Oct 25;366(6464):494-499. (PMID: 31467190)
Cell Res. 2010 Mar;20(3):256-75. (PMID: 20125123)
Immunol Rev. 2005 Oct;207:191-205. (PMID: 16181337)
Nat Rev Mol Cell Biol. 2008 Dec;9(12):944-57. (PMID: 19002207)
PLoS Biol. 2009 Mar 10;7(3):e54. (PMID: 19278296)
Cell Rep. 2020 Mar 3;30(9):2948-2962.e4. (PMID: 32130899)
Crit Rev Immunol. 2021;41(5):49-67. (PMID: 35381139)
Immunity. 2000 Mar;12(3):233-9. (PMID: 10755610)
Science. 2019 Dec 20;366(6472):1522-1527. (PMID: 31857486)
Nat Immunol. 2016 Nov;17(11):1300-1311. (PMID: 27668799)
Immunity. 2009 Jan 16;30(1):21-32. (PMID: 19119025)
Nat Commun. 2013;4:2142. (PMID: 23846752)
Proc Natl Acad Sci U S A. 2020 Nov 10;117(45):28232-28238. (PMID: 33097667)
J Cell Biol. 2008 Jan 14;180(1):159-72. (PMID: 18195106)
J Immunol. 2015 May 15;194(10):4641-9. (PMID: 25870247)
Elife. 2017 May 18;6:. (PMID: 28518056)
Nature. 1994 Aug 25;370(6491):647-50. (PMID: 8065450)
Nat Commun. 2018 Aug 22;9(1):3350. (PMID: 30135490)
Nat Biotechnol. 2020 Feb;38(2):199-209. (PMID: 31844290)
Curr Opin Immunol. 2015 Jun;34:28-34. (PMID: 25603223)
Sci Immunol. 2018 Jul 13;3(25):. (PMID: 30006464)
Protein J. 2019 Jun;38(3):317-329. (PMID: 31004255)
Nat Immunol. 2020 Apr;21(4):400-411. (PMID: 32123373)
Mol Immunol. 2011 Feb;48(5):769-75. (PMID: 21190736)
Sci Immunol. 2020 Jul 24;5(49):. (PMID: 32709702)
Annu Rev Immunol. 2013;31:443-73. (PMID: 23298205)
J Immunol. 2000 Jul 1;165(1):322-30. (PMID: 10861068)
Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):E3119-28. (PMID: 23898209)
Immunity. 2023 Jan 10;56(1):78-92.e6. (PMID: 36630919)
J Exp Med. 2014 Jul 28;211(8):1585-600. (PMID: 25049336)
J Infect Dis. 2023 Feb 1;227(3):391-401. (PMID: 34648018)
Traffic. 2006 Jun;7(6):663-72. (PMID: 16683916)
Nature. 2012 Nov 29;491(7426):717-23. (PMID: 23051753)
Mucosal Immunol. 2018 Nov;11(6):1591-1605. (PMID: 30115998)
Traffic. 2017 Jul;18(7):442-452. (PMID: 28471021)
Nat Commun. 2016 Aug 16;7:12506. (PMID: 27527800)
Science. 2019 Oct 25;366(6464):. (PMID: 31649166)
Science. 2017 Nov 24;358(6366):1064-1068. (PMID: 29025991)
Nat Immunol. 2020 Feb;21(2):178-185. (PMID: 31959982)
Blood. 2004 Mar 15;103(6):2187-95. (PMID: 14604956)
J Immunol. 2011 May 1;186(9):5039-45. (PMID: 21505216)
Semin Immunol. 2015 Mar;27(2):125-37. (PMID: 25887630)
Genes Immun. 2017 Jan;18(1):8-14. (PMID: 27881839)
Nature. 2003 Mar 13;422(6928):164-9. (PMID: 12634786)
Immunol Cell Biol. 2018 Jul;96(6):573-587. (PMID: 29656544)
PLoS Biol. 2010 Jun 29;8(6):e1000407. (PMID: 20613858)
Crit Rev Microbiol. 2017 Mar;43(2):196-209. (PMID: 27822970)
Signal Transduct Target Ther. 2021 Aug 4;6(1):291. (PMID: 34344870)
Biochem Biophys Res Commun. 2002 Jan 18;290(2):722-9. (PMID: 11785959)
Nat Commun. 2017 Mar 08;8:14599. (PMID: 28272391)
Cell Rep. 2019 Sep 17;28(12):3077-3091.e5. (PMID: 31533032)
Front Immunol. 2023 Feb 10;14:1107497. (PMID: 36845106)
J Cell Biol. 1994 Dec;127(6 Pt 1):1575-88. (PMID: 7798313)
Nat Med. 2016 Jan;22(1):26-36. (PMID: 26735408)
Sci Rep. 2019 Mar 18;9(1):4797. (PMID: 30886396)
Sci Rep. 2022 Dec 29;12(1):22539. (PMID: 36581641)
J Biol Chem. 1998 Oct 2;273(40):25915-21. (PMID: 9748267)
J Immunol. 2018 Nov 15;201(10):2862-2871. (PMID: 30397170)
Nat Immunol. 2019 Sep;20(9):1110-1128. (PMID: 31406380)
Curr Opin Immunol. 2021 Apr;69:10-17. (PMID: 33434741)
J Hepatol. 2016 May;64(5):1118-1127. (PMID: 26743076)
Immunol Cell Biol. 2022 Feb;100(2):112-126. (PMID: 34940995)
Curr Opin Immunol. 2020 Jun;64:124-129. (PMID: 32604057)
Nat Rev Immunol. 2006 Dec;6(12):919-29. (PMID: 17124513)
PLoS Genet. 2017 Jun 26;13(6):e1006862. (PMID: 28650991)
Traffic. 2005 Dec;6(12):1225-34. (PMID: 16262731)
Acc Chem Res. 2021 Sep 7;54(17):3462-3475. (PMID: 34415738)
Front Immunol. 2017 Feb 08;8:65. (PMID: 28228754)
Nat Rev Immunol. 2022 Dec;22(12):751-764. (PMID: 35418563)
J Cell Biol. 2022 Dec 5;221(12):. (PMID: 36129434)
Proc Natl Acad Sci U S A. 2020 Oct 6;117(40):24974-24985. (PMID: 32958637)
Nature. 2014 May 15;509(7500):361-5. (PMID: 24695216)
Front Immunol. 2020 Sep 02;11:2034. (PMID: 32983150)
Mol Cell Biochem. 2013 Aug;380(1-2):11-21. (PMID: 23677696)
J Immunol. 2000 Jan 1;164(1):292-9. (PMID: 10605023)
Chemistry. 2019 Dec 5;25(68):15594-15608. (PMID: 31529537)
Proc Natl Acad Sci U S A. 2016 May 24;113(21):E2983-92. (PMID: 27170188)
J Immunol. 1998 Oct 15;161(8):4066-77. (PMID: 9780177)
Nature. 1995 Jun 1;375(6530):411-5. (PMID: 7760935)
Semin Cell Dev Biol. 2018 Dec;84:58-64. (PMID: 30449535)
J Biol Chem. 2022 Feb;298(2):101542. (PMID: 34968463)
Nat Rev Immunol. 2007 Dec;7(12):929-41. (PMID: 18037897)
معلومات مُعتمدة: R01 AI148407 United States AI NIAID NIH HHS
المشرفين على المادة: 0 (Minor Histocompatibility Antigens)
0 (Histocompatibility Antigens Class I)
0 (Antigens)
0 (MR1 protein, human)
تواريخ الأحداث: Date Created: 20230929 Date Completed: 20240304 Latest Revision: 20240523
رمز التحديث: 20240523
مُعرف محوري في PubMed: PMC11108705
DOI: 10.1038/s41577-023-00934-1
PMID: 37773272
قاعدة البيانات: MEDLINE
الوصف
تدمد:1474-1741
DOI:10.1038/s41577-023-00934-1