دورية أكاديمية

The role of oxygen in the development and treatment of bronchopulmonary dysplasia.

التفاصيل البيبلوغرافية
العنوان: The role of oxygen in the development and treatment of bronchopulmonary dysplasia.
المؤلفون: Sotiropoulos JX; School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Australia; Department of Newborn Care, The Royal Hospital for Women, Randwick, New South Wales, Australia; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, University of Sydney, Australia., Oei JL; School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Australia; Department of Newborn Care, The Royal Hospital for Women, Randwick, New South Wales, Australia; NHMRC Clinical Trials Centre, Faculty of Medicine and Health, University of Sydney, Australia. Electronic address: j.oei@unsw.edu.au.
المصدر: Seminars in perinatology [Semin Perinatol] 2023 Oct; Vol. 47 (6), pp. 151814. Date of Electronic Publication: 2023 Sep 09.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 7801132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-075X (Electronic) Linking ISSN: 01460005 NLM ISO Abbreviation: Semin Perinatol Subsets: MEDLINE
أسماء مطبوعة: Publication: Philadelphia, PA : W.B. Saunders
Original Publication: New York, Grune & Stratton.
مواضيع طبية MeSH: Infant, Premature* , Bronchopulmonary Dysplasia*/prevention & control, Infant ; Infant, Newborn ; Humans ; Oxygen ; Morbidity ; Causality
مستخلص: Oxygen (O 2 ) is crucial for both the development and treatment of one of the most important consequences of prematurity: bronchopulmonary dysplasia (BPD). In fetal life, the hypoxic environment is important for alveolar development and maturation. After birth, O 2 becomes a double-edged sword. While O 2 is needed to prevent hypoxia, it also causes oxidative stress leading to a plethora of morbidities, including retinopathy and BPD. The advent of continuous O 2 monitoring with pulse oximeters has allowed clinicians to recognize the narrow therapeutic margins of oxygenation for the preterm infant, but more knowledge is needed to understand what these ranges are at different stages of the preterm infant's life, including at birth, in the neonatal intensive care unit and after hospital discharge. Future research, especially in innovative technologies such as automated O 2 control and remote oximetry, will improve the understanding and treatment of the O 2 needs of infants with BPD.
(Copyright © 2023 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: None
المشرفين على المادة: S88TT14065 (Oxygen)
تواريخ الأحداث: Date Created: 20231002 Date Completed: 20231120 Latest Revision: 20240109
رمز التحديث: 20240109
DOI: 10.1016/j.semperi.2023.151814
PMID: 37783577
قاعدة البيانات: MEDLINE
الوصف
تدمد:1558-075X
DOI:10.1016/j.semperi.2023.151814