دورية أكاديمية
Total Fertilization Failure: A Single Center Analysis.
| العنوان: | Total Fertilization Failure: A Single Center Analysis. |
|---|---|
| المؤلفون: | de Souza LK; Insemine Center for Human Reproduction, Porto Alegre, Brazil. lisiane@insemine.com., Witusk JPD; Insemine Center for Human Reproduction, Porto Alegre, Brazil., Galgaro BC; Insemine Center for Human Reproduction, Porto Alegre, Brazil., Rodrigues LDS; Insemine Center for Human Reproduction, Porto Alegre, Brazil., da Cunha-Filho JSL; Insemine Center for Human Reproduction, Porto Alegre, Brazil. |
| المصدر: | Reproductive sciences (Thousand Oaks, Calif.) [Reprod Sci] 2024 Mar; Vol. 31 (3), pp. 697-703. Date of Electronic Publication: 2023 Oct 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Springer Country of Publication: United States NLM ID: 101291249 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1933-7205 (Electronic) Linking ISSN: 19337191 NLM ISO Abbreviation: Reprod Sci Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2020- : [New York] : Springer Original Publication: Thousand Oaks, Calif. : Sage |
| مواضيع طبية MeSH: | Fertilization in Vitro* , Infertility*/therapy, Humans ; Male ; Female ; Pregnancy ; Sperm Injections, Intracytoplasmic ; Case-Control Studies ; Oocytes ; Anti-Mullerian Hormone ; Fertilization/physiology ; Pregnancy Rate |
| مستخلص: | Our main objective was to identify the male and female parameters associated with total fertilization failure (TFF) in IVF with nonmasculine indications. The present work, IRB equivalent INS 63209, is a case-control study that evaluated all cases with TFF after conventional IVF at the Center for Human Reproduction from January 2010 to December 2019 (n = 154). As a control group, we analyzed all patients who did not experience fertilization failure after conventional IVF in the same period (n = 475). We evaluated various parameters, both male and female, assessed during infertility treatment, and only cases without masculine etiology (normal seminal parameters) were included. Ages (female and male) were not different between the groups. Moreover, AMH (anti-Müllerian hormone), semen volume, preprocessing concentration and preprocessing motility were not significantly different (P > 0.05). However, the number of collected oocytes (study versus control groups, median [25-75 interquartile]: 2 [1-5] and 5 [3-8]); MII (2 [1-4] and 5 [2-7]); and postprocessing motility (85 [70-90] and 90 [80-95]) were significantly different between both groups (P < 0.05). Furthermore, a logistic regression analysis including all significant data demonstrated that the number of collected oocytes was significantly related to IVF failure. Patients with fewer than 5 oocytes had an OR of - 1.37 (- 0.938 to - 1.827) for TFF after conventional IVF. Our results showed that a lower follicular response to controlled ovarian stimulation, evidenced by a decreased number of collected oocytes, was the most important parameter associated with IVF failure in nonmasculine infertility. (© 2023. The Author(s), under exclusive licence to Society for Reproductive Investigation.) |
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| فهرسة مساهمة: | Keywords: Assisted reproductive technology (ART); Conventional in vitro fertilization (IVF); Fertilization; Total fertilization failure (TFF) |
| المشرفين على المادة: | 80497-65-0 (Anti-Mullerian Hormone) |
| تواريخ الأحداث: | Date Created: 20231009 Date Completed: 20240306 Latest Revision: 20240306 |
| رمز التحديث: | 20240306 |
| DOI: | 10.1007/s43032-023-01338-1 |
| PMID: | 37814199 |
| قاعدة البيانات: | MEDLINE |
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