دورية أكاديمية
Outcomes of Extracorporeal Life Support Utilization for Pediatric Patients With COVID-19 Infections.
| العنوان: | Outcomes of Extracorporeal Life Support Utilization for Pediatric Patients With COVID-19 Infections. |
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| المؤلفون: | Jacobson JC; From the Division of Pediatric Surgery, Children's Medical Center & Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas., Ryan ML; From the Division of Pediatric Surgery, Children's Medical Center & Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas., Vogel AM; Division of Pediatric Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas., Mehl SC; Division of Pediatric Surgery, Texas Children's Hospital and Baylor College of Medicine, Houston, Texas., Acker SN; Department of Pediatric Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado., Prendergast C; Department of Pediatric Surgery, Children's Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado., Padilla BE; Department of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona., Lee J; Department of Pediatric Surgery, Phoenix Children's Hospital, Phoenix, Arizona., Chao SD; Division of Pediatric Surgery, Stanford University School of Medicine, Palo Alto, California., Martin NR; Division of Pediatric Surgery, Stanford University School of Medicine, Palo Alto, California., Russell KW; Department of Pediatric Surgery, Primary Children's Hospital, University of Utah, Salt Lake City, Utah., Larsen K; Department of Pediatric Surgery, Primary Children's Hospital, University of Utah, Salt Lake City, Utah., Harting MT; Department of Pediatric Surgery, McGovern Medical School at the University of Texas Health Science Center at Houston and Children's Memorial Hermann Hospital, Houston, Texas., Linden AF; Section of Pediatric Surgery, Department of Surgery, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia., Ignacio RC Jr; Division of Pediatric Surgery/Department of Surgery, University of California School of Medicine, La Jolla, California., Slater BJ; Department of Surgery, University of Chicago Medicine, Chicago, Illinois., Juang D; Department of Pediatric Surgery, Children's Mercy Hospital, Kansas City, Missouri., Jensen AR; Department of Pediatric Surgery, UCSF Benioff Children's Hospitals, Oakland, California., Melhado CG; Department of Pediatric Surgery, UCSF Benioff Children's Hospitals, Oakland, California., Pelayo JC; Division of Pediatric Surgery and Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California., Zhong A; Division of Pediatric Surgery, Children's Hospital Los Angeles, Department of Surgery, Keck School of Medicine of USC, Los Angeles, California., Spencer BL; Department of Surgery, University of Michigan, Michigan Medicine, Ann Arbor, Michigan., Gadepalli SK; Section of Pediatric Surgery, Department of Surgery, University of Michigan, Mott Children's Hospital, Ann Arbor, Michigan.; Department of Pediatric Surgery, Susan B. Meister Child Health Evaluation and Research Center, Michigan Medicine, Ann Arbor, Michigan., Maamari M; Division of Critical Care Medicine, UT Southwestern Medical Center, Children's Medical Center, Dallas, Texas., Jimenez Valencia M; From the Division of Pediatric Surgery, Children's Medical Center & Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas., Qureshi FG; From the Division of Pediatric Surgery, Children's Medical Center & Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas., Pandya SR; From the Division of Pediatric Surgery, Children's Medical Center & Department of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas. |
| المصدر: | ASAIO journal (American Society for Artificial Internal Organs : 1992) [ASAIO J] 2024 Feb 01; Vol. 70 (2), pp. 146-153. Date of Electronic Publication: 2023 Oct 10. |
| نوع المنشور: | Observational Study; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 9204109 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-943X (Electronic) Linking ISSN: 10582916 NLM ISO Abbreviation: ASAIO J Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Hagerstown, MD : Lippincott Williams & Wilkins Original Publication: Philadelphia, PA : Published for the Society by J.B. Lippincott Co., c1992- |
| مواضيع طبية MeSH: | Extracorporeal Membrane Oxygenation*/adverse effects , COVID-19*/therapy, Humans ; Child ; Female ; Child, Preschool ; Adolescent ; Male ; Retrospective Studies ; Hospitalization ; Hospital Mortality |
| مستخلص: | Outcomes of pediatric patients who received extracorporeal life support (ECLS) for COVID-19 remain poorly described. The aim of this multi-institutional retrospective observational study was to evaluate these outcomes and assess for prognostic factors associated with in-hospital mortality. Seventy-nine patients at 14 pediatric centers across the United States who received ECLS support for COVID-19 infections between January 2020 and July 2022 were included for analysis. Data were extracted from the electronic medical record. The median age was 14.5 years (interquartile range [IQR]: 2-17 years). Most patients were female (54.4%) and had at least one pre-existing comorbidity (84.8%), such as obesity (44.3%, median body mass index percentile: 97% [IQR: 67.5-99.0%]). Venovenous (VV) ECLS was initiated in 50.6% of patients. Median duration of ECLS was 12 days (IQR: 6.0-22.5 days) with a mean duration from admission to ECLS initiation of 5.2 ± 6.3 days. Survival to hospital discharge was 54.4%. Neurological deficits were reported in 16.3% of survivors. Nonsurvivors were of older age (13.3 ± 6.2 years vs. 9.3 ± 7.7 years, p = 0.012), more likely to receive renal replacement therapy (63.9% vs. 30.2%, p = 0.003), demonstrated longer durations from admission to ECLS initiation (7.0 ± 8.1 days vs. 3.7 ± 3.8 days, p = 0.030), and had higher rates of ECLS-related complications (91.7% vs. 69.8%, p = 0.016) than survivors. Pediatric patients with COVID-19 who received ECLS demonstrated substantial morbidity and further investigation is warranted to optimize management strategies. Competing Interests: Disclosure: The authors have no funding and conflicts of interest to report. (Copyright © ASAIO 2023.) |
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| تواريخ الأحداث: | Date Created: 20231010 Date Completed: 20240131 Latest Revision: 20240301 |
| رمز التحديث: | 20240301 |
| DOI: | 10.1097/MAT.0000000000002059 |
| PMID: | 37816012 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1538-943X |
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| DOI: | 10.1097/MAT.0000000000002059 |