دورية أكاديمية
Articular involvement in Henoch-Schönlein Purpura: A review of literature.
| العنوان: | Articular involvement in Henoch-Schönlein Purpura: A review of literature. |
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| المؤلفون: | Gonzalez-Uribe V; Pediatric Allergy & Clinical Immunology Department, Hospital Infantil de Mexico Federico Gomez.; Facultad Mexicana de Medicina, Universidad La Salle Mexico City, Mexico., Martínez-Tenopala R; Facultad Mexicana de Medicina, Universidad La Salle Mexico City, Mexico., Solórzano-Anduiza AP; Facultad Mexicana de Medicina, Universidad La Salle Mexico City, Mexico., La Torre MF; Facultad Mexicana de Medicina, Universidad La Salle Mexico City, Mexico., Mojica-Gonzalez ZS; Pathology, Molecular Biology, and Immunohistochemistry, Hospital General de Mexico, Dr Eduardo Liceaga, Mexico City, Mexico. |
| المصدر: | Asian Pacific journal of allergy and immunology [Asian Pac J Allergy Immunol] 2023 Oct 23. Date of Electronic Publication: 2023 Oct 23. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Allergy and Immunology Society of Thailand Country of Publication: Thailand NLM ID: 8402034 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0125-877X (Print) Linking ISSN: 0125877X NLM ISO Abbreviation: Asian Pac J Allergy Immunol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Bangkok : Allergy and Immunology Society of Thailand Original Publication: [Bangkok : Bangkok Medical Publishers, c1983- |
| مستخلص: | Background: Henoch-Schönlein purpura (HSP), the most typical kind of pediatric vasculitis, can also affect adults. Over the last 10 years, research has been increasing on improvements in HSP diagnosis, physiopathology, symptoms, and therapy. Joint involvement is highly frequent in this condition; however, it typically undergoes spontaneous resolution and does not lead to long-term complications. Objective: To provide a deeper understanding of the constituting pathogenic mechanisms and clinical presentation of articular involvement, focusing on the effect of neutrophil activation on systemic small vessels. Methods: This literature review utilized a systematic search of academic databases, employing specific keywords to select recent peer-reviewed articles and scholarly sources on the topic. Results: The manifestations of joint involvement in HSP can vary in severity and frequency. Non-steroidal anti-inflammatory medications or acetaminophen are considered the first-line treatment for joint pain; however, corticosteroids may help achieve quick remission. In cases where standard treatment fails or manifestations persist, immunosuppressive drugs like rituximab, methotrexate, cyclophosphamide, or azathioprine have been used. Conclusions: While it tends to resolve without lasting joint damage, accurate diagnosis and appropriate management are crucial to ensure optimal patient outcomes. |
| تواريخ الأحداث: | Date Created: 20231024 Latest Revision: 20231024 |
| رمز التحديث: | 20240829 |
| DOI: | 10.12932/AP-220523-1622 |
| PMID: | 37874320 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 0125-877X |
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| DOI: | 10.12932/AP-220523-1622 |