دورية أكاديمية
أعرض في EDS

Contrast-Enhanced Mammography for Women with Palpable Breast Abnormalities.

التفاصيل البيبلوغرافية
العنوان: Contrast-Enhanced Mammography for Women with Palpable Breast Abnormalities.
المؤلفون: Amir T; Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, 10065, USA (T.A., K.P., M.H., D.T.K., J.S.S., M.S.J.)., Pinker K; Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, 10065, USA (T.A., K.P., M.H., D.T.K., J.S.S., M.S.J.)., Sevilimedu V; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, 10017, USA (V.S.)., Hughes M; Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, 10065, USA (T.A., K.P., M.H., D.T.K., J.S.S., M.S.J.)., Keating DT; Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, 10065, USA (T.A., K.P., M.H., D.T.K., J.S.S., M.S.J.)., Sung JS; Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, 10065, USA (T.A., K.P., M.H., D.T.K., J.S.S., M.S.J.)., Jochelson MS; Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York, 10065, USA (T.A., K.P., M.H., D.T.K., J.S.S., M.S.J.). Electronic address: jochelsm@mskcc.org.
المصدر: Academic radiology [Acad Radiol] 2024 Apr; Vol. 31 (4), pp. 1231-1238. Date of Electronic Publication: 2023 Nov 08.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
اللغة: English
بيانات الدورية: Publisher: Association Of University Radiologists Country of Publication: United States NLM ID: 9440159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4046 (Electronic) Linking ISSN: 10766332 NLM ISO Abbreviation: Acad Radiol Subsets: MEDLINE
أسماء مطبوعة: Publication: Reston Va : Association Of University Radiologists
Original Publication: Reston, VA : Association of University Radiologists, c1994-
مواضيع طبية MeSH: Mammography*/methods , Breast Neoplasms*/diagnostic imaging, Female ; Humans ; Middle Aged ; Retrospective Studies ; Prospective Studies ; Sensitivity and Specificity ; Predictive Value of Tests ; Breast/diagnostic imaging
مستخلص: Rationale and Objectives: To examine the role of contrast-enhanced mammography (CEM) in the work-up of palpable breast abnormalities.
Materials and Methods: In this single-center combination prospective-retrospective study, women with palpable breast abnormalities underwent CEM evaluation prospectively, comprising the acquisition of low energy (LE) images and recombined images (RI) which depict enhancement, followed by targeted ultrasound (US). Two independent readers retrospectively reviewed the imaging and assigned BI-RADS assessment based on LE alone, LE plus US, RI with LE plus US (CEM plus US), and RI alone. Pathology results or 1-year follow-up imaging served as the reference standard.
Results: 237 women with 262 palpable abnormalities were included (mean age, 51 years). Of the 262 palpable abnormalities, 116/262 (44%) had no imaging correlate and 242/262 (92%) were benign. RI alone had better specificity compared to LE plus US (Reader 1, 94% versus 89% (p = 0.009); Reader 2, 93% versus 88% (p = 0.03)), better positive predictive value (Reader 1, 52% versus 42% (p = 0.04); Reader 2, 53% versus 42% (p = 0.04)), and better accuracy (Reader 1, 93% versus 89% (p = 0.05); Reader 2, 93% versus 90% (p = 0.06)). CEM plus US was not significantly different in performance metrics versus LE plus US.
Conclusion: RI had better specificity compared to LE in combination with US. There was no difference in performance between CEM plus US and LE plus US, likely reflecting the weight US carries in radiologist decision-making. However, the results indicate that the absence of enhancement on RI in the setting of palpable lesions may help avoid benign biopsies.
Competing Interests: Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Katja Pinker reports a relationship with European Society of Breast Imaging that includes: speaking and lecture fees. Katja Pinker reports a relationship with Bayer that includes: speaking and lecture fees. Katja Pinker reports a relationship with Siemens Healthineers that includes: speaking and lecture fees. Katja Pinker reports a relationship with DKD 2019 that includes: speaking and lecture fees. Katja Pinker reports a relationship with Olea Medical that includes: speaking and lecture fees. Katja Pinker reports a relationship with Roche that includes: speaking and lecture fees. Katja Pinker reports a relationship with Genentech that includes: consulting or advisory. Katja Pinker reports a relationship with Merantix Healthcare that includes: consulting or advisory. Katja Pinker reports a relationship with AURA Health Technologies that includes: consulting or advisory. Katja Pinker reports a relationship with Guerbet that includes: consulting or advisory. Katja Pinker reports a relationship with Bayer that includes: consulting or advisory.
(Copyright © 2024 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.)
معلومات مُعتمدة: P30 CA008748 United States CA NCI NIH HHS
فهرسة مساهمة: Keywords: Contrast-enhanced mammography; Mammography; Ultrasonography
تواريخ الأحداث: Date Created: 20231110 Date Completed: 20240415 Latest Revision: 20240611
رمز التحديث: 20240611
DOI: 10.1016/j.acra.2023.10.027
PMID: 37949703
قاعدة البيانات: MEDLINE
الوصف
تدمد:1878-4046
DOI:10.1016/j.acra.2023.10.027