دورية أكاديمية
Normothermic Regional Perfusion in Controlled Donation After Circulatory Determination of Death Simultaneous Pancreas - Kidney Transplantation.
| العنوان: | Normothermic Regional Perfusion in Controlled Donation After Circulatory Determination of Death Simultaneous Pancreas - Kidney Transplantation. |
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| المؤلفون: | Gómez-Dueñas G; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GC18 Translational Research in Surgery of Solid Organ Transplantation - Maimonides Biomedical Research Institute of Cordoba, Spain., Durán M; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GC18 Translational Research in Surgery of Solid Organ Transplantation - Maimonides Biomedical Research Institute of Cordoba, Spain. Electronic address: manuduma@hotmail.com., Calleja-Lozano R; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GC18 Translational Research in Surgery of Solid Organ Transplantation - Maimonides Biomedical Research Institute of Cordoba, Spain., Arjona-Sánchez Á; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GE09 Research in Peritoneal and Retroperitoneal Oncological Surgery - Maimonides Biomedical Research Institute of Cordoba, Spain., Sánchez-Hidalgo JM; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GE09 Research in Peritoneal and Retroperitoneal Oncological Surgery - Maimonides Biomedical Research Institute of Cordoba, Spain., Rodríguez-Ortiz L; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GE09 Research in Peritoneal and Retroperitoneal Oncological Surgery - Maimonides Biomedical Research Institute of Cordoba, Spain., Ayllón-Terán MD; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GC18 Translational Research in Surgery of Solid Organ Transplantation - Maimonides Biomedical Research Institute of Cordoba, Spain., Campos-Hernández JP; Urology Department, Reina Sofía University Hospital, Cordoba, Spain., Rodríguez-Benot A; Nephrology Department, Reina Sofía University Hospital, Cordoba, Spain., Briceño J; Liver and Pancreas Transplantation Unit, General and Digestive Surgery Department, Reina Sofía University Hospital, Cordoba, Spain; GC18 Translational Research in Surgery of Solid Organ Transplantation - Maimonides Biomedical Research Institute of Cordoba, Spain. |
| المصدر: | Transplantation proceedings [Transplant Proc] 2023 Dec; Vol. 55 (10), pp. 2259-2261. Date of Electronic Publication: 2023 Nov 15. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Inc Country of Publication: United States NLM ID: 0243532 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2623 (Electronic) Linking ISSN: 00411345 NLM ISO Abbreviation: Transplant Proc Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York, N.Y. : Elsevier Science Inc. Original Publication: New York Stratton. |
| مواضيع طبية MeSH: | Kidney Transplantation*/adverse effects , Tissue and Organ Procurement*, Humans ; Brain Death ; Organ Preservation/adverse effects ; Perfusion ; Tissue Donors ; Graft Survival ; Pancreas ; Death ; Retrospective Studies |
| مستخلص: | Background: Simultaneous pancreas-kidney transplantation is the optimal treatment for patients with type 1 diabetes and renal failure. The use of pancreas grafts from donation after circulatory death (DCD), using normothermic regional perfusion (NRP), is still marginal worldwide, mainly due to possible additional risks of graft dysfunction and complications compared with grafts from donors after brain death. Methods: Case series of patients who underwent simultaneous pancreas-kidney transplantation after DCD-NRP between January 2018 and September 2022. This study evaluated early postoperative grafts and survival outcomes. Results: Four patients were included. One patient lost the pancreatic graft due to arterial thrombosis requiring transplantectomy. Another patient required a laparotomy due to hemoperitoneum. Overall, 1-year pancreas and kidney graft survival was 75% and 100%, respectively. One patient developed a lymphoma during the follow-up. Conclusion: The use of pancreas grafts from DCD after NRP preservation is safe and feasible. Comparative studies with donors after brain death grafts and larger series are required to confirm the feasibility of DCD-NRP pancreas transplantation. Competing Interests: Declaration of Competing Interest All the authors declare no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| تواريخ الأحداث: | Date Created: 20231116 Date Completed: 20231226 Latest Revision: 20231226 |
| رمز التحديث: | 20231227 |
| DOI: | 10.1016/j.transproceed.2023.09.007 |
| PMID: | 37973526 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1873-2623 |
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| DOI: | 10.1016/j.transproceed.2023.09.007 |