دورية أكاديمية
أعرض في EDS

Risk of head and neck cancer among opium users.

التفاصيل البيبلوغرافية
العنوان: Risk of head and neck cancer among opium users.
المؤلفون: Mohebbi E; Cellular and Molecular Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA., Alimoradi Z; Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran., Rozek LS; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington DC, USA., Mohebbi A; Dermatology Department, Kerman University of Medical Sciences, Kerman, Iran., Jafari E; Social Determinants of Health Research Center, Research Institute for Prevention of Non-Communicable Diseases, Qazvin University of Medical Sciences, Qazvin, Iran. Electronic address: elhejafari@gmail.com.
المصدر: Archives of oral biology [Arch Oral Biol] 2024 Jan; Vol. 157, pp. 105846. Date of Electronic Publication: 2023 Nov 08.
نوع المنشور: Meta-Analysis; Systematic Review; Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Pergamon Press Country of Publication: England NLM ID: 0116711 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1506 (Electronic) Linking ISSN: 00039969 NLM ISO Abbreviation: Arch Oral Biol Subsets: MEDLINE
أسماء مطبوعة: Publication: Oxford : Pergamon Press
Original Publication: Oxford, New York [etc.] Pergamon Press.
مواضيع طبية MeSH: Opium Dependence*/complications , Head and Neck Neoplasms*/epidemiology , Head and Neck Neoplasms*/etiology , Laryngeal Neoplasms*, Humans ; Opium/adverse effects ; Risk Factors
مستخلص: Objective: The scientific literature presents conflicting data on a possible causal relationship between opium users and the development of head and neck cancer (HNC). This study aimed to explore the risk of HNC among opium users is a narcotic addictive drug.
Design: A systematic review and meta-analysis encompassed academic databases and gray literature up to May 2023, focusing on epidemiologic observational studies that reported the effect size of the HNC risk and opium use.
Results: This study incorporated 14 effect size estimations to examine the association between opium use and the risk of head and neck cancers based on various HNC sub-sites, including the lip and oral cavity, pharynx, and larynx. The random effect model revealed a significant correlation between combined HNCs and opium use (odds ratio [OR]: 4.88; 95 % confidence interval [CI]: 2.99, 7.96). Additionally, opium consumption significantly increased the incidence of lip and oral cavity cancers (OR: 1.82; 95 % CI: 1.25, 2.65). Opium users faced an approximately eightfold increase in laryngeal cancer risk (OR: 7.86; 95 % CI: 4.66, 13.24) compared to non-opium users.
Conclusions: In summary, our findings strongly suggest that opium use is emerging as a significant risk factor for HNC. This underscores the need for further research and focused preventive measures to address this concerning association.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier Ltd. All rights reserved.)
فهرسة مساهمة: Keywords: Head and Neck Neoplasms; Laryngeal Neoplasms; Meta-Analysis; Oral Cavity Squamous Cell Carcinoma; Substance-related disorder
المشرفين على المادة: 8008-60-4 (Opium)
تواريخ الأحداث: Date Created: 20231119 Date Completed: 20231205 Latest Revision: 20231205
رمز التحديث: 20231215
DOI: 10.1016/j.archoralbio.2023.105846
PMID: 37980840
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-1506
DOI:10.1016/j.archoralbio.2023.105846