دورية أكاديمية
Natural supplements in antiphospholipid syndrome: A case for further study.
| العنوان: | Natural supplements in antiphospholipid syndrome: A case for further study. |
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| المؤلفون: | Kello N; Northwell Health, Division of Rheumatology, Donald and Barbara Zucker School of Medicine, Great Neck, NY, United States of America. Electronic address: nkello@northwell.edu., Cho YM; Northwell Health, Division of Rheumatology, Donald and Barbara Zucker School of Medicine, Great Neck, NY, United States of America. |
| المصدر: | Clinical immunology (Orlando, Fla.) [Clin Immunol] 2024 Jan; Vol. 258, pp. 109848. Date of Electronic Publication: 2023 Nov 28. |
| نوع المنشور: | Review; Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Academic Press Country of Publication: United States NLM ID: 100883537 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-7035 (Electronic) Linking ISSN: 15216616 NLM ISO Abbreviation: Clin Immunol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Orlando, FL : Academic Press, c1999- |
| مواضيع طبية MeSH: | Antiphospholipid Syndrome* , Venous Thromboembolism*/complications , Venous Thromboembolism*/drug therapy , Pregnancy Complications*/drug therapy, Female ; Pregnancy ; Humans ; Anticoagulants/therapeutic use ; Antibodies, Antiphospholipid |
| مستخلص: | Antiphospholipid syndrome (APS) is an autoimmune disorder characterized by thrombotic events and/or pregnancy complications in the presence of persistently positive antiphospholipid antibodies (aPL). Although long-term anticoagulation with vitamin K antagonists is considered standard of care, there is an unmet need for safe therapeutics as primary thromboprophylaxis or adjuncts to standard of care in APS. APS is driven by oxidative stress, procoagulant, proinflammatory and angiogenic pathways. For these reasons there has been an increased interest into the investigation of antithrombotic, anti-inflammatory and anti-oxidant properties of natural supplements in APS. The objective of this review is to summarize the mechanistic, epidemiologic and clinical evidence behind the use of natural supplements in APS, with a specific focus on vitamin D, omega-3 fatty acids, coenzyme Q10, gingerol, and isoquercetin. This review should serve as a compelling argument for the future study of natural supplements in APS. (Copyright © 2023 Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Antiphospholipid syndrome; Coenzyme Q10; Gingerol; Isoquercetin; Natural supplements; Omega-3 fatty acids; Vitamin D |
| المشرفين على المادة: | 0 (Anticoagulants) 0 (Antibodies, Antiphospholipid) |
| تواريخ الأحداث: | Date Created: 20231130 Date Completed: 20240102 Latest Revision: 20240410 |
| رمز التحديث: | 20240410 |
| DOI: | 10.1016/j.clim.2023.109848 |
| PMID: | 38036277 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1521-7035 |
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| DOI: | 10.1016/j.clim.2023.109848 |