دورية أكاديمية
'Testicular masquerade': a case report of testicular malignancy with persistent Müllerian duct syndrome and transverse testicular ectopia.
| العنوان: | 'Testicular masquerade': a case report of testicular malignancy with persistent Müllerian duct syndrome and transverse testicular ectopia. |
|---|---|
| المؤلفون: | Barki D; Bangalore Baptist Hospital, India., Manayath N; Bangalore Baptist Hospital, India., Vatsa BS; Bangalore Baptist Hospital, India., Venkatanarasimhan N S; Bangalore Baptist Hospital, India., Vishnuvardhana G V; Bangalore Baptist Hospital, India., Achar S; Bangalore Baptist Hospital, India., Bhat B; Bangalore Baptist Hospital, India. |
| المصدر: | Annals of the Royal College of Surgeons of England [Ann R Coll Surg Engl] 2024 May; Vol. 106 (5), pp. 466-470. Date of Electronic Publication: 2023 Dec 01. |
| نوع المنشور: | Journal Article; Case Reports |
| اللغة: | English |
| بيانات الدورية: | Publisher: Royal College of Surgeons of England Country of Publication: England NLM ID: 7506860 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1478-7083 (Electronic) Linking ISSN: 00358843 NLM ISO Abbreviation: Ann R Coll Surg Engl Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: London : Royal College of Surgeons of England |
| مواضيع طبية MeSH: | Testicular Neoplasms*/diagnosis , Testicular Neoplasms*/pathology , Testicular Neoplasms*/surgery , Testicular Neoplasms*/complications , Disorder of Sex Development, 46,XY*/diagnosis , Disorder of Sex Development, 46,XY*/complications , Testis*/abnormalities , Testis*/pathology , Testis*/surgery , Testis*/diagnostic imaging, Humans ; Male ; Middle Aged ; Cryptorchidism/diagnosis ; Cryptorchidism/surgery ; Cryptorchidism/complications ; Hernia, Inguinal/diagnosis ; Hernia, Inguinal/surgery ; Tomography, X-Ray Computed ; Choristoma/diagnosis ; Choristoma/complications ; Choristoma/pathology ; Seminoma/diagnosis ; Seminoma/surgery ; Seminoma/complications ; Seminoma/pathology |
| مستخلص: | Persistent Müllerian duct syndrome (PMDS) is a rare sexual development disorder. It is even more rarely associated with transverse testicular ectopia (TTE), a rare form of testicular ectopia, in which both testes descend through a single inguinal canal and are present in the same hemiscrotum. PMDS with TTE is associated with 18%-33% malignant transformation. Here we report the case of a 48-year-old man who presented with a large right inguinoscrotal swelling and on evaluation was found to have a large right testicular mass with complete right inguinal hernia, undescended left testis and a central abdominal mass. On evaluation with contrast-enhanced computed tomography abdomen and pelvis and image-guided biopsy he was diagnosed with mixed germ cell tumour of the right testis (predominantly a seminoma) with a retroperitoneal nodal mass and absent left testis, for which he received chemotherapy. Post-chemotherapy he underwent surgery and was diagnosed intraoperatively with PMDS along with TTE and testicular malignancy arising from the ectopic left testis. Postoperative recovery and follow-up were uneventful. Most cases of PMDS are diagnosed early in life. They present clinically with unilateral or bilateral undescended testis with inguinal hernia. In adults, PMDS is usually associated with male infertility. However, TTE is associated with an increased risk of testicular tumours if undiagnosed until adulthood. In adults PMDS with TTE is usually an intraoperative finding and is commonly associated with malignancy in the ectopic/undescended testis. |
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| فهرسة مساهمة: | Keywords: Mixed germ cell tumour; Persistent Müllerian duct syndrome (PMDS); Testicular malignancy; Transverse testicular ectopia (TTE); Undescended testis |
| SCR Disease Name: | Persistent Mullerian duct syndrome |
| تواريخ الأحداث: | Date Created: 20231201 Date Completed: 20240430 Latest Revision: 20240531 |
| رمز التحديث: | 20240601 |
| مُعرف محوري في PubMed: | PMC11060860 |
| DOI: | 10.1308/rcsann.2023.0088 |
| PMID: | 38038079 |
| قاعدة البيانات: | MEDLINE |
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