دورية أكاديمية
The morphology of the interfacial tissue between bighorn sheep horn and bony horncore increases contact surface to enhance strength and facilitate load transfer from the horn to the horncore.
| العنوان: | The morphology of the interfacial tissue between bighorn sheep horn and bony horncore increases contact surface to enhance strength and facilitate load transfer from the horn to the horncore. |
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| المؤلفون: | Fuller LH; Department of Biomedical Engineering, University of Massachusetts, Amherst, MA 01003, USA. Electronic address: lhfuller@umass.edu., Marcet EC; Department of Biomedical Engineering, University of Massachusetts, Amherst, MA 01003, USA., Agarkov LL; Department of Biomedical Engineering, University of Massachusetts, Amherst, MA 01003, USA., Singh P; Department of Biomedical Engineering, University of Massachusetts, Amherst, MA 01003, USA., Donahue SW; Department of Biomedical Engineering, University of Massachusetts, Amherst, MA 01003, USA. |
| المصدر: | Acta biomaterialia [Acta Biomater] 2024 Jan 15; Vol. 174, pp. 258-268. Date of Electronic Publication: 2023 Dec 09. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 101233144 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7568 (Electronic) Linking ISSN: 17427061 NLM ISO Abbreviation: Acta Biomater Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Kidlington, Oxford, UK : Elsevier, c2004- |
| مواضيع طبية MeSH: | Sheep, Bighorn* , Horns*/anatomy & histology , Brain Injuries*, Humans ; Animals ; Male ; Horses ; Sheep ; Skull ; Collagen/metabolism |
| مستخلص: | The horns of bighorn sheep rams are permanent cranial appendages used for high energy head-to-head impacts during interspecific combat. The horns attach to the underlying bony horncore by a layer of interfacial tissue that facilitates load transfer between the impacted horn and underlying horncore, which has been shown to absorb substantial energy during head impact. However, the morphology and mechanical properties of the interfacial tissue were previously unknown. Histomorphometry was used to quantify the interfacial tissue composition and morphology and lap-shear testing was used to quantify its mechanical properties. Histological analyses revealed the interfacial tissue is a complex network of collagen and keratin fibers, with collagen being the most abundant protein. Sharpey's fibers provide strong attachment between the interfacial tissue and horncore bone. The inner horn surface displayed microscopic porosity and branching digitations which increased the contact surface with the interfacial tissue by approximately 3-fold. Horn-horncore samples tested by lap-shear loading failed primarily at the horn surface, and the interfacial tissue displayed non-linear strain hardening behavior similar to other soft tissues. The elastic properties of the interfacial tissue (i.e., low- and high-strain shear moduli) were comparable to previously measured values for the equine laminar junction. The interfacial tissue contact surface was positively correlated with the interfacial tissue shear strength (1.23 ± 0.21 MPa), high-strain shear modulus (4.5 ± 0.7 MPa), and strain energy density (0.38 ± 0.07 MJ/m 3 ). STATEMENT OF SIGNIFICANCE: The bony horncore in bighorn sheep rams absorbs energy to reduce brain cavity accelerations and mitigate brain injury during head butting. The interfacial zone between the horn and horncore transfers energy from the impacted horn to the energy absorbing horncore but has been largely neglected in previous models of bighorn sheep ramming since interfacial tissue properties were previously unknown. This study quantified the morphology and mechanical properties of the horn-horncore interfacial tissue to better understand structure-property relationships that contribute to energy transfer during ramming. Results from this study will improve models of bighorn sheep ramming used to study mechanisms of brain injury mitigation and may inspire novel materials and structures for brain injury prevention in humans. Competing Interests: Declaration of Competing Interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2023 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Bighorn sheep; Bony horncore; Horn; Interfacial tissue; Material properties |
| المشرفين على المادة: | 9007-34-5 (Collagen) |
| تواريخ الأحداث: | Date Created: 20231210 Date Completed: 20240102 Latest Revision: 20240620 |
| رمز التحديث: | 20240620 |
| DOI: | 10.1016/j.actbio.2023.12.008 |
| PMID: | 38072223 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1878-7568 |
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| DOI: | 10.1016/j.actbio.2023.12.008 |