التفاصيل البيبلوغرافية
| العنوان: |
Pathogens stabilize or destabilize depending on host stage structure. |
| المؤلفون: |
Hite JL; University of Wisconsin-Madison, Department of Pathobiological Sciences, School of Veterinary Medicine, Madison, Wisconsin, USA., Roos AM; Institute for Biodiversity and Ecosystem Dynamics, University of Amsterdam, Amsterdam, the Netherlands; Santa Fe Institute, Santa Fe, NM 87501, USA. |
| المصدر: |
Mathematical biosciences and engineering : MBE [Math Biosci Eng] 2023 Nov 10; Vol. 20 (12), pp. 20378-20404. |
| نوع المنشور: |
Journal Article |
| اللغة: |
English |
| بيانات الدورية: |
Publisher: American Institute of Mathematical Sciences;; _b Beihang University Country of Publication: United States NLM ID: 101197794 Publication Model: Print Cited Medium: Internet ISSN: 1551-0018 (Electronic) Linking ISSN: 15471063 NLM ISO Abbreviation: Math Biosci Eng Subsets: MEDLINE |
| أسماء مطبوعة: |
Original Publication: Springfield, MO, USA : [S.l.] : American Institute of Mathematical Sciences; Beihang University |
| مواضيع طبية MeSH: |
Ecosystem* , Communicable Diseases*/epidemiology, Humans ; Biomass ; Disease Outbreaks ; Host-Pathogen Interactions |
| مستخلص: |
A common assumption is that pathogens more readily destabilize their host populations, leading to an elevated risk of driving both the host and pathogen to extinction. This logic underlies many strategies in conservation biology and pest and disease management. Yet, the interplay between pathogens and population stability likely varies across contexts, depending on the environment and traits of both the hosts and pathogens. This context-dependence may be particularly important in natural consumer-host populations where size- and stage-structured competition for resources strongly modulates population stability. Few studies, however, have examined how the interplay between size and stage structure and infectious disease shapes the stability of host populations. Here, we extend previously developed size-dependent theory for consumer-resource interactions to examine how pathogens influence the stability of host populations across a range of contexts. Specifically, we integrate a size- and stage-structured consumer-resource model and a standard epidemiological model of a directly transmitted pathogen. The model reveals surprisingly rich dynamics, including sustained oscillations, multiple steady states, biomass overcompensation, and hydra effects. Moreover, these results highlight how the stage structure and density of host populations interact to either enhance or constrain disease outbreaks. Our results suggest that accounting for these cross-scale and bidirectional feedbacks can provide key insight into the structuring role of pathogens in natural ecosystems while also improving our ability to understand how interventions targeting one may impact the other. |
| فهرسة مساهمة: |
Keywords: bistability; eco-epidemiological feedbacks; hydra effect; overcompensation; stage-structure; virulence |
| تواريخ الأحداث: |
Date Created: 20231221 Date Completed: 20231222 Latest Revision: 20231222 |
| رمز التحديث: |
20231222 |
| DOI: |
10.3934/mbe.2023901 |
| PMID: |
38124557 |
| قاعدة البيانات: |
MEDLINE |
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