دورية أكاديمية
The Assessment of Radial Peripapillary Capillary Vessel Density in Adult Children of Patients With Primary Open Angle Glaucoma.
العنوان: | The Assessment of Radial Peripapillary Capillary Vessel Density in Adult Children of Patients With Primary Open Angle Glaucoma. |
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المؤلفون: | Bayraktar S; The University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Hondur G; The University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Şekeroğlu MA; The University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Altaş FB; The University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Yeşilyaprak N; The University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Çevik S; The University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Şen E; The University of Health Sciences, Ulucanlar Eye Training and Research Hospital, Ankara, Turkey., Elgin U; Dünyagöz Eye Hospital, Ankara, Turkey. |
المصدر: | Journal of glaucoma [J Glaucoma] 2024 Jul 01; Vol. 33 (7), pp. e43-e48. Date of Electronic Publication: 2023 Dec 21. |
نوع المنشور: | Journal Article; Comparative Study |
اللغة: | English |
بيانات الدورية: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 9300903 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-481X (Electronic) Linking ISSN: 10570829 NLM ISO Abbreviation: J Glaucoma Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2015- > : Philadelphia, PA : Wolters Kluwer Health, Inc. Original Publication: New York, N.Y. : Raven Press, c1992- |
مواضيع طبية MeSH: | Glaucoma, Open-Angle*/diagnosis , Glaucoma, Open-Angle*/physiopathology , Tomography, Optical Coherence*/methods , Nerve Fibers*/pathology , Retinal Vessels*/diagnostic imaging , Retinal Vessels*/pathology , Capillaries*/pathology , Capillaries*/diagnostic imaging , Optic Disk*/blood supply , Retinal Ganglion Cells*/pathology , Intraocular Pressure*/physiology , Visual Fields*/physiology, Humans ; Female ; Male ; Adult ; Microvascular Density ; Fluorescein Angiography/methods ; Middle Aged |
مستخلص: | Prcis: The observed decrease in radial peripapillary capillary vessel density among adult children of individuals with primary open angle glaucoma, in comparison to controls, suggests the possibility of early microvascular alterations in the eyes of these at-risk individuals. Purpose: To compare the radial peripapillary capillary vessel density (RPCVD) and peripapillary retinal nerve fiber layer (RNFL) thickness values of eyes between healthy adults with a maternal or paternal history of primary open angle glaucoma (POAG) and age-matched healthy controls without a family history of POAG. Materials and Methods: RPCVD values and RNFL thicknesses in the peripapillary region and 4 quadrants (superior, inferior, nasal, and temporal) were evaluated using optical coherence tomography angiography among 30 adult children of patients with POAG and 30 age-matched healthy controls without a family history of POAG. Results: The mean whole image RPCVD (51.6±1.7% vs. 49.8±1.7%, P =0.0006) and average RPCVD (54.7±1.7% vs. 53.2±2.1%, P =0.006) values were significantly lower in the adult children of patients with POAG compared with age-matched healthy controls without a family history of POAG. There was no difference in terms of RNFL thickness values in any region. Conclusion: Despite having similar RNFL thickness values to the control group, the observation of lower RPCVD in the eyes of adult children of POAG patients may indicate potential early vascular alterations. The result of the present study encourages further longitudinal studies to determine the potential importance of the underlying vascular alterations in these high-risk individuals. Competing Interests: Disclosure: The authors declare no conflict of interest. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.) |
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تواريخ الأحداث: | Date Created: 20231222 Date Completed: 20240626 Latest Revision: 20240626 |
رمز التحديث: | 20240626 |
DOI: | 10.1097/IJG.0000000000002347 |
PMID: | 38129936 |
قاعدة البيانات: | MEDLINE |
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