دورية أكاديمية
Cardiovascular Risk Age Reflects Arterial Status: Middle-Aged People Showed Equivalent Arterial Stiffness to Older People in the Same Risk Category.
| العنوان: | Cardiovascular Risk Age Reflects Arterial Status: Middle-Aged People Showed Equivalent Arterial Stiffness to Older People in the Same Risk Category. |
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| المؤلفون: | Alves-Cabratosa L; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol)., Elosua-Bayés M; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol)., Martí-Lluch R; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol).; Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS).; Institut d'Investigacio Biomedica de Girona (IdIBGi)., Blanch J; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol)., Tornabell-Noguera È; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol).; Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)., Garcia-Gil M; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol)., Ponjoan A; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol).; Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS).; Institut d'Investigacio Biomedica de Girona (IdIBGi)., Grau M; Serra Hunter Fellow, Department of Medicine, University of Barcelona.; Biomedical Research Consortium in Epidemiology and Public Health (CIBERESP).; August Pi i Sunyer Biomedical Research Institute (IDIBAPS)., Ribas-Aulinas F; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol).; Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)., Zacarías-Pons L; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol).; Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS)., Marrugat J; Registre Gironi del Cor (REGICOR) Grupo de investigacion en epidemiologia y genetica cardiovascular (EGEC), Institut Hospital del Mar d'Investigacions Mediques (IMIM).; CIBER Enfermedades Cardiovasculares., Ramos R; Grup Investigacio en Salut Cardiovascular de Girona (ISV-Girona). Institut Universitari d'Investigacio en Atencio Primaria Jordi Gol (IDIAP Jordi Gol).; Network for Research on Chronicity, Primary Care, and Health Promotion (RICAPPS).; Institut d'Investigacio Biomedica de Girona (IdIBGi).; Departament de Ciencies Mediques, Universitat de Girona.; Serveis d'Atencio Primaria, Girona. Institut Catala de Salut (ICS). |
| المصدر: | Journal of atherosclerosis and thrombosis [J Atheroscler Thromb] 2024 May 01; Vol. 31 (5), pp. 626-640. Date of Electronic Publication: 2023 Dec 28. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Japan Atherosclerosis Society Country of Publication: Japan NLM ID: 9506298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1880-3873 (Electronic) Linking ISSN: 13403478 NLM ISO Abbreviation: J Atheroscler Thromb Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Tokyo : Japan Atherosclerosis Society |
| مواضيع طبية MeSH: | Vascular Stiffness*/physiology , Cardiovascular Diseases*/physiopathology , Cardiovascular Diseases*/epidemiology , Cardiovascular Diseases*/diagnosis , Pulse Wave Analysis* , Ankle Brachial Index* , Heart Disease Risk Factors*, Humans ; Male ; Female ; Middle Aged ; Cross-Sectional Studies ; Aged ; Adult ; Aged, 80 and over ; Age Factors ; Risk Factors |
| مستخلص: | Aim: The concept of risk age may help overcome an excessive weight of age in cardiovascular risk functions. This study aimed to evaluate the equivalence of risk age with arterial stiffness by comparing people with increased risk age and individuals with the same chronological and risk age. In order to materialize this aim, we categorized individuals based on cardiovascular risk and compared groups with increased risk factors (other than age) and groups with normal levels. Methods: This is a cross-sectional population-level study carried out in Girona province within the context of the REGICOR study (Girona Heart Registry). In this study, individuals aged 35-90 years who had a brachial-ankle pulse wave velocity measurement and with no previous cardiovascular disease or peripheral arterial disease were included. Cardiovascular risk was estimated with the FRESCO (in 35-79 year-olds), SCORE2 (in 35-69 year-olds), and SCORE2-OP (in 70-90 year-olds) functions and categorized to calculate and compare (in each category) the median chronological age in the group with increased risk factors and the reference. Arterial stiffness was assessed with the brachial-ankle pulse wave velocity (baPWV). The analyses were carried out separately by sex. Results: In this study, 2499 individuals were included, with a mean age of 59.7 and 46.9% of men. Men presented worse health condition, including a higher mean cardiovascular disease risk score. Both men and women with increased levels of risk factors showed worse health condition than the respective men and women with optimal levels. In each risk category, the groups with higher risk age than chronological age (increased risk factors) were similar in baPWV values to the groups with the same chronological and risk ages (reference), who were consistently older. Conclusions: In categories with the same cardiovascular risk, the arterial stiffness of participants with a higher risk factor burden (increased risk age) matched that of older participants with the rest of the risk factors at optimal levels (same chronological and risk age). These results support the guidelines on the utilization of risk age to explain heightened cardiovascular risk, particularly among individuals in middle age. |
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| فهرسة مساهمة: | Keywords: Arterial stiffness; Cardiovascular risk; Prevention; Risk age; Risk factors |
| تواريخ الأحداث: | Date Created: 20240103 Date Completed: 20240501 Latest Revision: 20240511 |
| رمز التحديث: | 20240511 |
| مُعرف محوري في PubMed: | PMC11079498 |
| DOI: | 10.5551/jat.64541 |
| PMID: | 38171907 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1880-3873 |
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| DOI: | 10.5551/jat.64541 |