دورية أكاديمية
أعرض في EDS

Sialic acid in human milk and infant formulas in China: concentration, distribution and type.

التفاصيل البيبلوغرافية
العنوان: Sialic acid in human milk and infant formulas in China: concentration, distribution and type.
المؤلفون: Lv Y; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China.; Quanzhou Center for Disease Control and Prevention, Quanzhou, Fujian Province, 362000, People's Republic of China., Wang X; Department of Nutrition, Zhongshan Hospital (Xiamen), Fudan University, Xiamen, Fujian Province, 361015, People's Republic of China.; Xiamen Clinical Research Center for Cancer Therapy, Xiamen, Fujian Province, 361015, People's Republic of China., Huang J; Department of Clinical Nutrition, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi Province, 330006, People's Republic of China., Zhang W; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China., Zhu M; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China., Dekyi K; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China., Zhang Y; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China., Zheng L; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China., Li H; State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China.
المصدر: The British journal of nutrition [Br J Nutr] 2024 May 14; Vol. 131 (9), pp. 1506-1512. Date of Electronic Publication: 2024 Jan 05.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
اللغة: English
بيانات الدورية: Publisher: Published on behalf of the Nutrition Society by CABI Publishing Country of Publication: England NLM ID: 0372547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2662 (Electronic) Linking ISSN: 00071145 NLM ISO Abbreviation: Br J Nutr Subsets: MEDLINE
أسماء مطبوعة: Publication: <2000->: Wallingford, Oxon, UK : Published on behalf of the Nutrition Society by CABI Publishing
Original Publication: [Cambridge, New York] Cambridge University Press.
مواضيع طبية MeSH: Infant Formula*/chemistry , Milk, Human*/chemistry , N-Acetylneuraminic Acid*/analysis, Female ; Humans ; Infant ; Infant, Newborn ; Male ; Breast Feeding ; China ; Colostrum/chemistry ; Infant Nutritional Physiological Phenomena ; Oligosaccharides/analysis
مستخلص: This study compared the concentrations, types and distributions of sialic acid (SA) in human milk at different stages of the postnatal period with those in a range of infant formulas. Breast milk from mothers of healthy, full-term and exclusively breastfed infants was collected on the 2nd ( n 246), 7th ( n 135), 30th ( n 85) and 90th ( n 48) day after birth. The SA profiles of human milk, including their distribution, were analysed and compared with twenty-four different infant formulas. Outcome of this observational study was the result of natural exposure. Only SA of type Neu5Ac was detected in human milk. Total SA concentrations were highest in colostrum and reduced significantly over the next 3 months. Approximately 68·7–76·1 % of all SA in human milk were bound to oligosaccharides. Two types of SA, Neu5Ac and Neu5Gc, have been detected in infant formulas. Most SA was present in infant formulas combined with protein. Breastfed infants could receive more SA than formula-fed infants with the same energy intake. Overall, human milk is a preferable source of SA than infant formulas in terms of total SA content, dynamics, distribution and type. These SA profiles in the natural state are worth to be considered by the production of formulas because they may have a great effect on infant nutrition and development.
فهرسة مساهمة: Keywords: China; Human milk oligosaccharides; Infant formula; Neu5Ac; Neu5Gc
المشرفين على المادة: GZP2782OP0 (N-Acetylneuraminic Acid)
0 (Oligosaccharides)
تواريخ الأحداث: Date Created: 20240105 Date Completed: 20240424 Latest Revision: 20240502
رمز التحديث: 20240503
DOI: 10.1017/S0007114524000011
PMID: 38178715
قاعدة البيانات: MEDLINE
الوصف
تدمد:1475-2662
DOI:10.1017/S0007114524000011