دورية أكاديمية
Population-Based Data Linkage Describing Patterns of Cancer Clinical Trial Enrollment Among Children and Adolescents.
| العنوان: | Population-Based Data Linkage Describing Patterns of Cancer Clinical Trial Enrollment Among Children and Adolescents. |
|---|---|
| المؤلفون: | Siegel DA; Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA., Durbin EB; Kentucky Cancer Registry, Markey Cancer Center, University of Kentucky, Lexington, KY., Pollock BH; University of California Davis Comprehensive Cancer Center, Sacramento, CA., Grimes A; University of Texas Health Science Center at San Antonio, San Antonio, TX., Ji L; Children's Oncology Group, Monrovia, CA.; University of Southern California, Los Angeles, CA., Alonzo TA; Children's Oncology Group, Monrovia, CA.; University of Southern California, Los Angeles, CA., Vargas SL; Children's Oncology Group, Monrovia, CA., Huang B; Kentucky Cancer Registry, Markey Cancer Center, University of Kentucky, Lexington, KY., McDowell JR; Kentucky Cancer Registry, Markey Cancer Center, University of Kentucky, Lexington, KY., Lycan E; Kentucky Cancer Registry, Markey Cancer Center, University of Kentucky, Lexington, KY., Ransdell P; Kentucky Cancer Registry, Markey Cancer Center, University of Kentucky, Lexington, KY., Tai E; Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA., Roth ME; Division of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, TX., Freyer DR; University of Southern California, Los Angeles, CA.; Children's Hospital Los Angeles, Los Angeles, CA. |
| المصدر: | JCO oncology practice [JCO Oncol Pract] 2024 May; Vol. 20 (5), pp. 631-642. Date of Electronic Publication: 2024 Jan 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101758685 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2688-1535 (Electronic) Linking ISSN: 26881527 NLM ISO Abbreviation: JCO Oncol Pract Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Alexandria, Va. : American Society of Clinical Oncology, [2020]- |
| مواضيع طبية MeSH: | Neoplasms*/therapy , Neoplasms*/epidemiology , Clinical Trials as Topic*, Humans ; Adolescent ; Child ; Female ; Male ; Child, Preschool ; Infant ; Infant, Newborn ; Registries ; Young Adult ; Patient Selection ; Information Storage and Retrieval |
| مستخلص: | Purpose: Database linkage between cancer registries and clinical trial consortia has the potential to elucidate referral patterns of children and adolescents with newly diagnosed cancer, including enrollment into cancer clinical trials. This study's primary objective was to assess the feasibility of this linkage approach. Methods: Patients younger than 20 years diagnosed with incident cancer during 2012-2017 in the Kentucky Cancer Registry (KCR) were linked with patients enrolled in a Children's Oncology Group (COG) study. Matched patients between databases were described by sex, age, race and ethnicity, geographical location when diagnosed, and cancer type. Logistic regression modeling identified factors associated with COG study enrollment. Timeliness of patient identification by KCR was reported through the Centers for Disease Control and Prevention's Early Case Capture (ECC) program. Results: Of 1,357 patients reported to KCR, 47% were determined by matching to be enrolled in a COG study. Patients had greater odds of enrollment if they were age 0-4 years ( v 15-19 years), reported from a COG-affiliated institution, and had renal cancer, neuroblastoma, or leukemia. Patients had lower odds of enrollment if Hispanic ( v non-Hispanic White) or had epithelial (eg, thyroid, melanoma) cancer. Most (59%) patients were reported to KCR within 10 days of pathologic diagnosis. Conclusion: Linkage of clinical trial data with cancer registries is a feasible approach for tracking patient referral and clinical trial enrollment patterns. Adolescents had lower enrollment compared with younger age groups, independent of cancer type. Population-based early case capture could guide interventions designed to increase cancer clinical trial enrollment. |
| References: | J Registry Manag. 2016 Winter;43(4):174-8. (PMID: 29595920) J Clin Oncol. 2007 Oct 10;25(29):4616-21. (PMID: 17925557) Pediatr Blood Cancer. 2019 Jan;66(1):e27426. (PMID: 30256525) J Oncol Pract. 2016 Apr;12(4):e388-95. (PMID: 27026648) Pediatr Blood Cancer. 2015 Aug;62(8):1337-44. (PMID: 25755225) Cancer. 2005 May 1;103(9):1891-7. (PMID: 15795902) Cancer. 2022 Jul 15;128(14):2760-2767. (PMID: 35482017) Cancer. 2018 Oct 15;124(20):4064-4071. (PMID: 30291804) Pediatr Blood Cancer. 2020 Apr;67(4):e28023. (PMID: 31556250) Pediatr Blood Cancer. 2022 Nov;69(11):e29933. (PMID: 36069432) Cancer. 2007 Feb 1;109(3):465-76. (PMID: 17200964) J Cancer Surviv. 2022 Jun;16(3):487-496. (PMID: 33899161) Cancer. 2003 Mar 1;97(5):1339-45. (PMID: 12599243) JAMA Netw Open. 2022 Mar 1;5(3):e223687. (PMID: 35315914) J Rural Health. 2017 Sep;33(4):375-381. (PMID: 27602545) Oncologist. 2017 Aug;22(8):1002-1005. (PMID: 28408619) PLoS One. 2020 Apr 23;15(4):e0230824. (PMID: 32324751) J Pediatr Hematol Oncol. 2006 Jan;28(1):17-22. (PMID: 16394887) Cancer Epidemiol Biomarkers Prev. 2020 Apr;29(4):796-806. (PMID: 32066621) J Registry Manag. 2019 Summer;46(2):30-36. (PMID: 32010425) JCO Clin Cancer Inform. 2021 Sep;5:1034-1043. (PMID: 34662145) Pediatrics. 2014 Jun;133 Suppl 3:S98-S103. (PMID: 24918214) Cancer. 2005 Apr 1;103(7):1457-67. (PMID: 15712273) Cancer. 2014 Oct 1;120(19):3007-15. (PMID: 24889136) Cancer. 2015 Dec 15;121(24):4398-406. (PMID: 26393950) J Registry Manag. 2013 Spring;40(1):40-7. (PMID: 23778697) Public Health Rep. 2016 Jan-Feb;131(1):126-36. (PMID: 26843678) Semin Oncol. 2020 Feb;47(1):56-64. (PMID: 32229032) J Natl Cancer Inst. 2023 Nov 8;115(11):1337-1354. (PMID: 37433078) |
| معلومات مُعتمدة: | UG1 CA189955 United States CA NCI NIH HHS; CC999999 United States ImCDC Intramural CDC HHS; P30 CA177558 United States CA NCI NIH HHS; U10 CA180899 United States CA NCI NIH HHS; U10 CA180886 United States CA NCI NIH HHS |
| تواريخ الأحداث: | Date Created: 20240109 Date Completed: 20240513 Latest Revision: 20240607 |
| رمز التحديث: | 20240607 |
| مُعرف محوري في PubMed: | PMC11090697 |
| DOI: | 10.1200/OP.23.00325 |
| PMID: | 38194612 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 2688-1535 |
|---|---|
| DOI: | 10.1200/OP.23.00325 |