دورية أكاديمية
Sensitive electrochemiluminescence immunosensor based on a novel luminescent europium metal-organic framework and antenna effect for detecting pro-gastrin-releasing peptide.
| العنوان: | Sensitive electrochemiluminescence immunosensor based on a novel luminescent europium metal-organic framework and antenna effect for detecting pro-gastrin-releasing peptide. |
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| المؤلفون: | Xu L; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China., Hu S; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China., Yang J; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China., Wang N; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China., Wu Y; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China., Deng B; State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, China. Electronic address: dengby16@163.com. |
| المصدر: | Talanta [Talanta] 2024 Apr 01; Vol. 270, pp. 125644. Date of Electronic Publication: 2024 Jan 07. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3573 (Electronic) Linking ISSN: 00399140 NLM ISO Abbreviation: Talanta Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Amsterdam : Elsevier Original Publication: Oxford : Pergamon Press |
| مواضيع طبية MeSH: | Metal-Organic Frameworks* , Biosensing Techniques* , Metal Nanoparticles*, Humans ; Gastrin-Releasing Peptide ; Europium ; Luminescent Measurements ; Electrochemical Techniques ; Immunoassay ; Limit of Detection |
| مستخلص: | Sensitive detection of pro-gastrin-releasing peptide (Pro-GRP) is crucial because it is a highly sensitive and specific tumor marker for small cell lung cancer. Herein, we synthesized an efficient luminescent europium metal-organic framework and developed a sandwich ECL immunosensor for the sensitive detection of Pro-GRP, which used Eu 3+ as the central ion and 2,4,6-tri (4-carboxyphenyl)-1,3,5-triazine (H3TATB) as the organic ligand. H3TATB acted as a strong absorbing reagent and transferred its energy to Eu 3+ via the antenna effect to enhance the ECL response signal of Eu 3+ . As per calculations, the ECL efficiency of Eu-TATB, which was a promising ECL luminophore, was up to 130 %. The Cu2O cube worked as a substrate to assist the electron transfer and was used as a co-reaction accelerator to catalyze S Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Antenna effect; Co-reaction accelerator; Europium ion; Metal–organic framework; Pro-gastrin-releasing peptide |
| المشرفين على المادة: | 0 (Metal-Organic Frameworks) 80043-53-4 (Gastrin-Releasing Peptide) 444W947O8O (Europium) |
| تواريخ الأحداث: | Date Created: 20240113 Date Completed: 20240129 Latest Revision: 20240129 |
| رمز التحديث: | 20240129 |
| DOI: | 10.1016/j.talanta.2024.125644 |
| PMID: | 38218005 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-3573 |
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| DOI: | 10.1016/j.talanta.2024.125644 |