دورية أكاديمية

The relationship between prognostic nutritional index and long-term mortality in patients undergoing emergency coronary artery bypass graft surgery for acute-ST elevation myocardial infarction.

التفاصيل البيبلوغرافية
العنوان: The relationship between prognostic nutritional index and long-term mortality in patients undergoing emergency coronary artery bypass graft surgery for acute-ST elevation myocardial infarction.
عنوان ترانسليتريتد: Akut ST yükselmeli miyokard infarktüsü nedeniyle acil koroner arter bypass greft cerrahisi uygulanan hastalarda prognostik beslenme indeksi ile uzun dönem mortalite arasındaki ilişki.
المؤلفون: Demirci G; Department of Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul-Türkiye., Hasdemir H; Department of Cardiology, Istanbul Acıbadem University, Atakent Hospital, İstanbul-Türkiye., Şahin A; Department of Cardiology, Istanbul Istinye University, Liv Bahcesehir Hospital, İstanbul-Türkiye., Demir AR; Department of Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul-Türkiye., Çelik Ö; Department of Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul-Türkiye., Uzun F; Department of Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul-Türkiye., Yildiz M; Department of Cardiology, Istanbul Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul-Türkiye.
المصدر: Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES [Ulus Travma Acil Cerrahi Derg] 2024 Jan; Vol. 30 (1), pp. 13-19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: KARE Yayıncılık Country of Publication: Turkey NLM ID: 101274231 Publication Model: Print Cited Medium: Internet ISSN: 1307-7945 (Electronic) Linking ISSN: 1306696X NLM ISO Abbreviation: Ulus Travma Acil Cerrahi Derg Subsets: MEDLINE
أسماء مطبوعة: Publication: Kadıköy, İstanbul : KARE Yayıncılık
Original Publication: [Istanbul] : Ulusal Travma ve Acil Cerrahi Derneği, [2003]-
مواضيع طبية MeSH: ST Elevation Myocardial Infarction*/surgery , ST Elevation Myocardial Infarction*/etiology , Coronary Artery Disease*/complications , Coronary Artery Disease*/surgery , Percutaneous Coronary Intervention*/adverse effects, Humans ; Nutrition Assessment ; Prognosis ; Coronary Artery Bypass/adverse effects ; Retrospective Studies ; Risk Factors ; Treatment Outcome
مستخلص: Background: Malnutrition and the prognosis of coronary artery disease (CAD) are shown to be correlated. The significance of nutritional status has been evaluated in patients with ST elevation myocardial infarction (STEMI), stable CAD, and elective coronary artery bypass graft (CABG) surgery. However, the prognostic impact of poor nutritional status on STEMI patients who underwent emergent CABG is not known. In this study, we aimed to investigate the relationship between nutritional status assessed by the prognostic nutritional index (PNI) and long-term mortality in STEMI patients who underwent emergent CABG. To the best of our knowledge, our study is the first one to evaluate the PNI effect on this specific population.
Methods: 131 consecutive patients with STEMI who did not qualify for primary percutaneous coronary intervention and required emergent CABG between 2013 and 2018 were included in our study. The study population was divided into two groups: survivors and non-survivors. The PNI was calculated as 10 × serum albumin (g/dL) + 0.005 × total lymphocyte count (per mm3) for both groups, using the preoperative data. The optimal cut-off value was obtained by receiver operating characteristic (ROC) analysis. According to the cut-off value, we investigated the relationship between PNI and long-term mortality.
Results: The mean age of the study population was 57.0±10.6. During the median 92.7 (70.0-105.3)-month follow-up, 32 of the 131 patients (24.4%) died. Regression analysis showed a significant association between glucose levels (hazard ratio (HR), 1.007; 95% confidence interval (CI), 1.002-1.012; p=0.011) and PNI (HR, 0.850; 95% CI, 0.787-0.917; p<0.001) and long-term mortality. Accord-ing to the ROC analysis, the cut-off value for PNI to predict all-cause mortality was found to be 44.9, with a sensitivity of 81.3% and a specificity of 89.9%. In addition, age, ejection fraction, glomerular filtration rate, Killip classification, and left anterior descending-left internal mammary artery graft use are significantly associated with long-term all-cause mortality in STEMI patients undergoing emergency CABG.
Conclusion: The PNI was significantly associated with long-term mortality in patients with STEMI who underwent emergent CABG. PNI can be used to improve the accuracy of the risk assessment of STEMI patients undergoing emergent CABG.
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تواريخ الأحداث: Date Created: 20240116 Date Completed: 20240117 Latest Revision: 20240330
رمز التحديث: 20240330
مُعرف محوري في PubMed: PMC10977484
DOI: 10.14744/tjtes.2023.44082
PMID: 38226577
قاعدة البيانات: MEDLINE
الوصف
تدمد:1307-7945
DOI:10.14744/tjtes.2023.44082