دورية أكاديمية
Virtual calibration for in vivo measurement of Pb-210 activity in the skull using BOMAB, MIRD, and MIDA phantoms.
| العنوان: | Virtual calibration for in vivo measurement of Pb-210 activity in the skull using BOMAB, MIRD, and MIDA phantoms. |
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| المؤلفون: | Meng X; College of Nuclear Science and Technology, Beijing Normal University, Joint Laboratory of Jinping Ultra-low Radiation Background Measurement of Ministry of Ecology and Environment Beijing Normal University, Key Laboratory of Beam Technology of Ministry of Education, Beijing, 100875, China., Liu Y; College of Nuclear Science and Technology, Beijing Normal University, Joint Laboratory of Jinping Ultra-low Radiation Background Measurement of Ministry of Ecology and Environment Beijing Normal University, Key Laboratory of Beam Technology of Ministry of Education, Beijing, 100875, China. Electronic address: yyliu@bnu.edu.cn., Wu B; College of Nuclear Science and Technology, Beijing Normal University, Joint Laboratory of Jinping Ultra-low Radiation Background Measurement of Ministry of Ecology and Environment Beijing Normal University, Key Laboratory of Beam Technology of Ministry of Education, Beijing, 100875, China. Electronic address: bwu6@bnu.edu.cn., Wang Y; College of Nuclear Science and Technology, Beijing Normal University, Joint Laboratory of Jinping Ultra-low Radiation Background Measurement of Ministry of Ecology and Environment Beijing Normal University, Key Laboratory of Beam Technology of Ministry of Education, Beijing, 100875, China., Wang J; College of Nuclear Science and Technology, Beijing Normal University, Joint Laboratory of Jinping Ultra-low Radiation Background Measurement of Ministry of Ecology and Environment Beijing Normal University, Key Laboratory of Beam Technology of Ministry of Education, Beijing, 100875, China., Cheng J; College of Nuclear Science and Technology, Beijing Normal University, Joint Laboratory of Jinping Ultra-low Radiation Background Measurement of Ministry of Ecology and Environment Beijing Normal University, Key Laboratory of Beam Technology of Ministry of Education, Beijing, 100875, China. |
| المصدر: | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine [Appl Radiat Isot] 2024 Mar; Vol. 205, pp. 111192. Date of Electronic Publication: 2024 Jan 17. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Pergamon Press Country of Publication: England NLM ID: 9306253 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-9800 (Electronic) Linking ISSN: 09698043 NLM ISO Abbreviation: Appl Radiat Isot Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford ; New York : Pergamon Press, c1993- |
| مواضيع طبية MeSH: | Whole-Body Counting*/methods , Lead*, Computer Simulation ; Calibration ; Monte Carlo Method ; Lead Radioisotopes ; Skull ; Phantoms, Imaging |
| مستخلص: | The counting efficiency calibration for in vivo measurement is crucial to derive the activity of radionuclides residing inside a monitored subject. Recently, virtual calibration based on computational phantoms has become popular, yet some key questions remain unresolved. Here, we focus on the in vivo measurement of Pb-210 in the skull and systematically examine how virtual calibration compares to those using physical phantoms and how the variety of computational phantoms affects the derived counting efficiency. It is found that the virtually calibrated efficiency based on the MIDA phantom, which characterizes the highest anatomical fidelity, shows reasonable consistency with the experimental counterpart, with a relative bias of approximately 10%. However, in comparison to the case based on the MIDA phantom, those based on the BOMAB and MIRD phantoms show larger deviation, demonstrating underestimations on the counting efficiency by 51% and 42%, respectively. This finding underscores the critical role of computational phantoms in the virtual calibration. This study contributes to the development of techniques for assessing lung cancer risk resulting from chronic radon exposure through in vivo measurement of skeletal Pb-210 activity. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Head phantom; In vivo measurement; Pb-210 burden; Virtual calibration |
| المشرفين على المادة: | 2P299V784P (Lead) 0 (Lead-210) 0 (Lead Radioisotopes) |
| تواريخ الأحداث: | Date Created: 20240121 Date Completed: 20240205 Latest Revision: 20240205 |
| رمز التحديث: | 20240205 |
| DOI: | 10.1016/j.apradiso.2024.111192 |
| PMID: | 38245995 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1872-9800 |
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| DOI: | 10.1016/j.apradiso.2024.111192 |