تقرير
Feasibility of PiB positron emission tomography/computed tomography for treatment monitoring with Tafamidis in a patient with transthyretin cardiac amyloidosis.
العنوان: | Feasibility of PiB positron emission tomography/computed tomography for treatment monitoring with Tafamidis in a patient with transthyretin cardiac amyloidosis. |
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المؤلفون: | Fujioka K; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Norikane T; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan. Electronic address: norikane.takashi.gv@kagawa-u.ac.jp., Takami Y; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Yamamoto Y; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Noma T; Department of Cardiorenal and Cerebrovascular Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan., Nishiyama Y; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan. |
المصدر: | Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2024 Mar; Vol. 33, pp. 101816. Date of Electronic Publication: 2024 Jan 20. |
نوع المنشور: | Case Reports |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Inc. on behalf of American Society of Nuclear Cardiology Country of Publication: United States NLM ID: 9423534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6551 (Electronic) Linking ISSN: 10713581 NLM ISO Abbreviation: J Nucl Cardiol Subsets: MEDLINE |
أسماء مطبوعة: | Publication: 2024- : New York : Elsevier Inc. on behalf of American Society of Nuclear Cardiology Original Publication: St. Louis, MO : Mosby-Year Book, Inc., c1994- |
مواضيع طبية MeSH: | Amyloidosis*/diagnostic imaging , Amyloidosis*/drug therapy , Cardiomyopathies*/diagnostic imaging , Cardiomyopathies*/drug therapy , Benzoxazoles*, Female ; Humans ; Aged ; Positron Emission Tomography Computed Tomography ; Prealbumin ; Feasibility Studies |
مستخلص: | We present a 77-year-old woman with wild-type ATTR cardiac amyloidosis (ATTR-CA) who presented with dyspnea, arrhythmia, and elevated NT-pro BNP. Initial imaging including cardiac MRI, PYP scintigraphy, PiB PET/CT and NaF PET/CT revealed cardiac abnormalities. Tafamidis treatment was initiated. After 14 months, symptomatic improvement and reduced NT-pro BNP were observed. Cardiac MRI and PYP scintigraphy showed no significant change and increased NaF accumulation, while PiB PET/CT showed decreased amyloid deposition, suggesting that it may be superior to NaF PET/CT in assessing the therapeutic effect of tafamidis in ATTR-CA. (Copyright © 2024. Published by Elsevier Inc.) |
فهرسة مساهمة: | Keywords: (11)C-PiB positron emission tomography (PET); (18)F–NaF PET; ATTR-CA |
المشرفين على المادة: | 8FG9H9D31J (tafamidis) 0 (Prealbumin) 0 (Benzoxazoles) |
تواريخ الأحداث: | Date Created: 20240121 Date Completed: 20240313 Latest Revision: 20240313 |
رمز التحديث: | 20240313 |
DOI: | 10.1016/j.nuclcard.2024.101816 |
PMID: | 38246259 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1532-6551 |
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DOI: | 10.1016/j.nuclcard.2024.101816 |