Feasibility of PiB positron emission tomography/computed tomography for treatment monitoring with Tafamidis in a patient with transthyretin cardiac amyloidosis.

التفاصيل البيبلوغرافية
العنوان: Feasibility of PiB positron emission tomography/computed tomography for treatment monitoring with Tafamidis in a patient with transthyretin cardiac amyloidosis.
المؤلفون: Fujioka K; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Norikane T; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan. Electronic address: norikane.takashi.gv@kagawa-u.ac.jp., Takami Y; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Yamamoto Y; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan., Noma T; Department of Cardiorenal and Cerebrovascular Medicine, Faculty of Medicine, Kagawa University, Kagawa, Japan., Nishiyama Y; Department of Radiology, Faculty of Medicine, Kagawa University, Kagawa, Japan.
المصدر: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology [J Nucl Cardiol] 2024 Mar; Vol. 33, pp. 101816. Date of Electronic Publication: 2024 Jan 20.
نوع المنشور: Case Reports
اللغة: English
بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society of Nuclear Cardiology Country of Publication: United States NLM ID: 9423534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6551 (Electronic) Linking ISSN: 10713581 NLM ISO Abbreviation: J Nucl Cardiol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2024- : New York : Elsevier Inc. on behalf of American Society of Nuclear Cardiology
Original Publication: St. Louis, MO : Mosby-Year Book, Inc., c1994-
مواضيع طبية MeSH: Amyloidosis*/diagnostic imaging , Amyloidosis*/drug therapy , Cardiomyopathies*/diagnostic imaging , Cardiomyopathies*/drug therapy , Benzoxazoles*, Female ; Humans ; Aged ; Positron Emission Tomography Computed Tomography ; Prealbumin ; Feasibility Studies
مستخلص: We present a 77-year-old woman with wild-type ATTR cardiac amyloidosis (ATTR-CA) who presented with dyspnea, arrhythmia, and elevated NT-pro BNP. Initial imaging including cardiac MRI, PYP scintigraphy, PiB PET/CT and NaF PET/CT revealed cardiac abnormalities. Tafamidis treatment was initiated. After 14 months, symptomatic improvement and reduced NT-pro BNP were observed. Cardiac MRI and PYP scintigraphy showed no significant change and increased NaF accumulation, while PiB PET/CT showed decreased amyloid deposition, suggesting that it may be superior to NaF PET/CT in assessing the therapeutic effect of tafamidis in ATTR-CA.
(Copyright © 2024. Published by Elsevier Inc.)
فهرسة مساهمة: Keywords: (11)C-PiB positron emission tomography (PET); (18)F–NaF PET; ATTR-CA
المشرفين على المادة: 8FG9H9D31J (tafamidis)
0 (Prealbumin)
0 (Benzoxazoles)
تواريخ الأحداث: Date Created: 20240121 Date Completed: 20240313 Latest Revision: 20240313
رمز التحديث: 20240313
DOI: 10.1016/j.nuclcard.2024.101816
PMID: 38246259
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-6551
DOI:10.1016/j.nuclcard.2024.101816